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Questions and Answers
What is Advair Diskus?
What are the indications for Advair Diskus?
Indicated for the twice-daily maintenance treatment of airflow obstruction in patients with COPD, including chronic bronchitis and/or emphysema.
What is the route and dosage for Advair Diskus?
1 puff twice a day.
Which classifications do fluticasone and salmeterol belong to?
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What are the actions of salmeterol?
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Advair Diskus is indicated for the relief of acute bronchospasm.
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What are some adverse effects of Advair Diskus?
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What interactions should be monitored with Advair Diskus?
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Fluticasone is classified as a ______.
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Salmeterol is classified as a ______.
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Match the following terms with their definitions:
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Study Notes
Advair Diskus Overview
- Contains a combination of fluticasone propionate and salmeterol xinafoate.
- Available in three formulations: ADVAIR DISKUS 100/50, 250/50, and 500/50.
- Approved for use in patients aged 4 years and older for asthma and chronic obstructive pulmonary disease (COPD).
Pharmaceutical Classification
- Fluticasone: classified as corticosteroids.
- Salmeterol: classified as adrenergics.
Therapeutic Classification
- Fluticasone serves as an anti-inflammatory (steroidal) agent.
- Salmeterol acts as a bronchodilator.
Indications
- Prescribed for twice-daily maintenance treatment of airflow obstruction in COPD patients.
- Beneficial for those with chronic bronchitis and/or emphysema.
Mechanism of Action
- Fluticasone decreases inflammation in the airways.
- Salmeterol activates beta2-adrenergic receptors, increasing cyclic adenosine monophosphate (cAMP) levels, leading to bronchodilation.
Contraindications and Precautions
- Not for the relief of acute bronchospasm.
- Avoid using additional long-acting beta-agonists (LABAs).
Adverse Effects
- Possible bronchospasm, heart palpitations, tremors, and respiratory difficulties.
- Serious risks include asthma-related death and oral thrush (thrush is the fungal infection in the mouth).
Drug Interactions
- Beta blockers may reduce therapeutic effects of Advair Diskus.
- MAO inhibitors and tricyclic antidepressants can enhance cardiovascular side effects.
Administration and Dosage
- Delivered via inhalation (PO).
- Typical dosage: 1 puff twice a day.
Nursing Implications
- Prior to administration, assess lung sounds, pulse, and blood pressure.
- Rinse mouth with water after using the device to reduce the risk of thrush.
- Label the date of foil pouch opening and the "use by" date (1 month later).
- Ensure the patient understands the correct inhalation technique and confirms correct medication delivery.
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Description
Test your knowledge about Advair Diskus and its components with these flashcards. Explore definitions, pharmacological classifications, and therapeutic uses of fluticasone and salmeterol. Ideal for students and healthcare professionals alike.
