18 Questions
What is the term for cancer that has spread to a different part of the body from the primary location?
Metastasis
Which chemotherapeutic agent interferes with the way the body breaks down folate?
Methotrexate
What is the term for cancer that starts in the skin or in tissues lining internal organs?
Carcinoma
How does Vincristine act on cells during chemotherapy?
Binds tubulin and prevents microtubule formation
Which of the following is a type of bone marrow cancer?
Multiple Myeloma
What is the mechanism of action of Tamoxifen used in breast cancer treatment?
Functions as an estrogen antagonist
Which of the following is a pyrimidine analog used as an antineoplastic agent to treat multiple solid tumors?
Fluorouracil (5-FU)
What is the period after chemotherapy when blood counts are at their lowest point called?
Nadir
Which of the following is used in patients who have certain cancers and neutropenia caused by some types of chemotherapy?
Colony-stimulating factor (CSF)
What is the purpose of colony-stimulating factor (CSF)?
To help the bone marrow make more white blood cells
When should chemotherapy NOT be given?
All of the above
Which of the following statements is TRUE about chemotherapy?
It can cause long-term sterility in both males and females
What enzyme present in the blood can convert large amounts of purines into uric acid?
Xanthine oxidase
What is the mechanism of action of Allopurinol in tumor lysis syndrome?
Inhibits xanthine oxidase activity
Which medication converts uric acid to a more water-soluble metabolite for excretion?
Rasburicase
What complication can arise if uric acid crystals damage the kidneys?
Acute renal failure
In what context might higher doses of Allopurinol be used, and for how long?
$400 - 800 mg/day for 10 - 14 days
What does ER+ cancer mean in relation to breast cancer treatment?
Cancer that responds to hormone therapy targeting Estrogen Receptors
Test your knowledge about Fluorouracil (5-FU), a pyrimidine analog used as an antineoplastic agent to treat multiple solid tumors. Explore its mechanism of action, interactions, and clinical applications.
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