Fluorouracil (5-FU) as an Antineoplastic Agent Quiz
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Questions and Answers

What is the term for cancer that has spread to a different part of the body from the primary location?

  • Carcinoma
  • Osteosarcoma
  • Metastasis (correct)
  • Maid Sarcoma
  • Which chemotherapeutic agent interferes with the way the body breaks down folate?

  • Vincristine
  • Methotrexate (correct)
  • Vinca Alkaloid
  • Cyclophosphamide
  • What is the term for cancer that starts in the skin or in tissues lining internal organs?

  • Leukemia
  • Osteosarcoma
  • Carcinoma (correct)
  • Multiple Myeloma
  • How does Vincristine act on cells during chemotherapy?

    <p>Binds tubulin and prevents microtubule formation</p> Signup and view all the answers

    Which of the following is a type of bone marrow cancer?

    <p>Multiple Myeloma</p> Signup and view all the answers

    What is the mechanism of action of Tamoxifen used in breast cancer treatment?

    <p>Functions as an estrogen antagonist</p> Signup and view all the answers

    Which of the following is a pyrimidine analog used as an antineoplastic agent to treat multiple solid tumors?

    <p>Fluorouracil (5-FU)</p> Signup and view all the answers

    What is the period after chemotherapy when blood counts are at their lowest point called?

    <p>Nadir</p> Signup and view all the answers

    Which of the following is used in patients who have certain cancers and neutropenia caused by some types of chemotherapy?

    <p>Colony-stimulating factor (CSF)</p> Signup and view all the answers

    What is the purpose of colony-stimulating factor (CSF)?

    <p>To help the bone marrow make more white blood cells</p> Signup and view all the answers

    When should chemotherapy NOT be given?

    <p>All of the above</p> Signup and view all the answers

    Which of the following statements is TRUE about chemotherapy?

    <p>It can cause long-term sterility in both males and females</p> Signup and view all the answers

    What enzyme present in the blood can convert large amounts of purines into uric acid?

    <p>Xanthine oxidase</p> Signup and view all the answers

    What is the mechanism of action of Allopurinol in tumor lysis syndrome?

    <p>Inhibits xanthine oxidase activity</p> Signup and view all the answers

    Which medication converts uric acid to a more water-soluble metabolite for excretion?

    <p>Rasburicase</p> Signup and view all the answers

    What complication can arise if uric acid crystals damage the kidneys?

    <p>Acute renal failure</p> Signup and view all the answers

    In what context might higher doses of Allopurinol be used, and for how long?

    <p>$400 - 800 mg/day for 10 - 14 days</p> Signup and view all the answers

    What does ER+ cancer mean in relation to breast cancer treatment?

    <p>Cancer that responds to hormone therapy targeting Estrogen Receptors</p> Signup and view all the answers

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