JC HBHD 2 Week 1 Chapter 21 Fluid and Electrolytes
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Questions and Answers

What is the approximate total body water volume in liters for a healthy, nonobese 70-kg male?

  • 20 L
  • 30 L
  • 50 L
  • 40 L (correct)
  • How does fat content affect total body water?

  • Higher fat content leads to higher total body water.
  • Fat content has no impact on total body water.
  • Higher fat content leads to lower total body water. (correct)
  • Higher fat content leads to a more stable total body water.
  • What is the approximate percentage of body weight attributed to water in a newborn infant?

  • 60%
  • 40%
  • 50%
  • 80% (correct)
  • Which of the following factors contributes to the variation in total body water?

    <p>Gender (C)</p> Signup and view all the answers

    Which of the following is not a body fluid compartment?

    <p>Blood serum (C)</p> Signup and view all the answers

    What is the underlying cause of water intoxication?

    <p>Excessive intake of water without sufficient electrolyte replenishment. (A)</p> Signup and view all the answers

    Which of these is NOT a characteristic of electrolytes?

    <p>They include compounds like glucose. (B)</p> Signup and view all the answers

    What is pitting edema?

    <p>Swelling caused by high interstitial fluid volume, where depressions in the skin do not rapidly refill. (A)</p> Signup and view all the answers

    Which hormone plays a key role in restoring normal extracellular fluid volume?

    <p>Aldosterone. (C)</p> Signup and view all the answers

    What is a cation?

    <p>A positively charged ion like potassium (K+) or sodium (Na+). (B)</p> Signup and view all the answers

    What is the main cause of hypernatremia?

    <p>A relative deficit of water to salt in extracellular fluid (A)</p> Signup and view all the answers

    A patient presents with skeletal muscle weakness, paralysis, and cardiac arrest. Which electrolyte imbalance is most likely present?

    <p>Hyperkalemia (D)</p> Signup and view all the answers

    Which of the following conditions can cause hypocalcemia?

    <p>Pancreatitis (A)</p> Signup and view all the answers

    What is the primary symptom associated with both hypernatremia and hyponatremia?

    <p>Central nervous system malfunction (A)</p> Signup and view all the answers

    A patient with a history of prolonged diarrhea is suspected of having an electrolyte imbalance. Which electrolyte imbalance is most likely to be present?

    <p>Hypernatremia (D)</p> Signup and view all the answers

    Which condition is characterized by increased neuromuscular irritability, including cramping, muscle twitching, and hyperactive reflexes?

    <p>Hypocalcemia (C)</p> Signup and view all the answers

    Which of the following is NOT a cause of hyperkalemia?

    <p>Excessive secretion of antidiuretic hormone (B)</p> Signup and view all the answers

    Which electrolyte imbalance is most commonly associated with the use of certain laxatives and diuretics?

    <p>Hypokalemia (C)</p> Signup and view all the answers

    Which of the following statements accurately describes the role of antidiuretic hormone (ADH) in fluid balance?

    <p>ADH is released from the posterior pituitary gland when ECF volume is low, promoting water reabsorption in the kidneys. (A)</p> Signup and view all the answers

    Which fluid compartment contains the largest volume of water in the human body?

    <p>Intracellular fluid (ICF) (D)</p> Signup and view all the answers

    What is the primary function of aldosterone in regulating fluid balance?

    <p>Aldosterone stimulates the kidneys to reabsorb sodium and water, decreasing urine output and increasing ECF volume. (A)</p> Signup and view all the answers

    How does increased capillary blood pressure influence fluid movement in the body?

    <p>Increased capillary blood pressure promotes fluid movement from the bloodstream into the interstitial fluid. (A)</p> Signup and view all the answers

    What is the primary source of metabolic water in the body?

    <p>Cellular respiration (B)</p> Signup and view all the answers

    Which of the following is NOT a direct contributor to fluid output in the human body?

    <p>Liver (D)</p> Signup and view all the answers

    How does the body compensate for inadequate fluid intake when thirst sensation is not triggered?

    <p>The body conserves available fluids by decreasing saliva production and fluid output. (C)</p> Signup and view all the answers

    Which of the following statements best describes the concept of dehydration?

    <p>Dehydration occurs only when fluid output exceeds intake for an extended period. (C)</p> Signup and view all the answers

    Flashcards

    Body Fluid Volume Variation

    Total body water varies by weight, fat, gender, and age.

    Body Fluid Compartments

    Body fluids are divided into plasma, interstitial fluid, and intracellular fluid.

    Fluid Balance Mechanisms

    The body uses several mechanisms to maintain fluid balance.

    Electrolyte Importance

    Electrolytes are vital for many body functions, including fluid balance.

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    Common Fluid Imbalances

    Fluid imbalances can lead to dehydration or overhydration.

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    Overhydration

    A condition where fluid intake exceeds output, leading to excess body fluid volume.

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    Water intoxication

    Severe overhydration causing potentially life-threatening neurological impairment and electrolyte imbalance.

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    Electrolytes

    Compounds that dissociate in water into ions, essential for body fluid balance.

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    Cations

    Positively charged ions, such as potassium (K+) and sodium (Na+).

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    Pitting edema

    Swelling from high interstitial fluid volume; persists when pressure is applied to the skin.

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    Electrolyte Imbalance

    Disruption in homeostatic control of electrolyte levels in body fluids.

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    Hypernatremia

    Blood sodium level greater than 145 mEq/L; water deficit relative to salt in ECF.

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    Hyponatremia

    Blood sodium level less than 136 mEq/L; too much water for sodium in ECF.

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    Hyperkalemia

    Blood potassium level more than 5.1 mEq/L, causing muscle malfunction.

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    Hypokalemia

    Blood potassium level less than 3.5 mEq/L, causing cardiac and skeletal issues.

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    Hypercalcemia

    Blood calcium levels exceeding 10.5 mg/dL; leads to decreased neuromuscular activity.

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    Hypocalcemia

    Blood calcium levels less than 8.4 mg/dL; causes increased neuromuscular irritability.

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    CNS Symptoms of Sodium Imbalances

    Headache, confusion, seizures, and coma from sodium imbalances.

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    Extracellular Fluid (ECF)

    The fluid that surrounds cells and transports substances.

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    Intracellular Fluid (ICF)

    The largest fluid compartment located inside cells.

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    Fluid Intake Sources

    Ways the body gains fluid: drinking liquids, food, and metabolism.

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    Fluid Output Sources

    Ways the body loses fluid: respiration, sweating, urine, and feces.

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    Antidiuretic Hormone (ADH)

    A hormone that conserves water during low ECF volume.

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    Fluid Imbalance - Dehydration

    Condition where total body fluid volume is less than normal.

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    Capillary Blood Pressure Effects

    High blood pressure moves fluid from blood to interstitial fluid.

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    Regulation of Fluid Intake

    Hypothalamus signals thirst when ECF volume changes.

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    Study Notes

    Fluid & Electrolyte Balance

    • Fluid balance is crucial for bodily functions
    • Body fluid volumes vary depending on age, gender, and body weight
    • Average 70kg nonobese male has about 40L
    • Body fluid is 80% of newborn infants and 60% in adult males and 50% in adult females

    Body Fluid Volumes

    • Body water is the most abundant compound
    • Plasma: 3 liters
    • Interstitial fluid: 12 liters
    • Intracellular fluid: 25 liters

    Body Fluid Compartments

    • Extracellular fluid (ECF): Surrounds cells and transports substances
    • Plasma: Liquid portion of whole blood
    • Interstitial fluid: Surrounds cells
    • Transcellular: Lymph, joint fluids, cerebrospinal fluid, and eye humors
    • Intracellular fluid (ICF): Located inside cells, facilitates chemical reactions

    Sources of Fluid Intake and Output

    • Fluid intake: Liquids, water in food, metabolic water
    • Fluid output: Water vapor from respiration, sweat, urine, feces

    Regulation of Fluid Output

    • Main organs are lungs, skin, kidneys, and large intestine
    • Fluid output (mainly urine volume) is regulated according to fluid intake
    • Antidiuretic hormone (ADH) from the posterior pituitary gland affects ECF balance when volume is low
    • Aldosterone from the adrenal cortex increases kidney tubule reabsorption of sodium and water

    Regulation of Fluid Intake

    • Sensory receptors detect changes in ECF volume and concentration, then send signals to the hypothalamus
    • The hypothalamus causes a feeling of thirst which triggers drinking
    • When fluid intake is insufficient, the body may compensate by reducing saliva production and other fluids

    Capillary Blood Pressure and Blood Proteins

    • Increased capillary blood pressure leads to fluid shifting from blood to interstitial fluid (IF)
    • Blood plasma protein concentration contributes to osmotic pressure drawing water into plasma

    Fluid Imbalances

    • Dehydration: Total body fluid volume is smaller than normal, IF shrinks first followed by ICF and plasma if untreated
    • Overhydration: Total body fluid volume is higher than normal; burdens heart function

    Importance of Electrolytes in Body Fluids

    • Nonelectrolytes: Organic substances that don't dissociate in water
    • Electrolytes: Compounds that dissociate in water into ions

    Ions

    • Ions are the dissociated particles of electrolytes that carry electrical charges
    • Cations are positively charged (e.g., potassium [K+], sodium [Na+])
    • Anions are negatively charged (e.g., chloride [Cl-], bicarbonate [HCO3-], anionic proteins)

    Electrolytes Found in Fluid Compartments of the Body

    • Specific concentrations in plasma, interstitial fluid, and intracellular fluid for major electrolytes.

    Pitting Edema

    • Swelling caused by high interstitial fluid volume, depressions in skin do not rapidly refill

    Sodium-Containing Internal Secretions

    • Examples are saliva, gastric secretions, pancreatic secretions, bile, and intestinal secretions

    Electrolyte Imbalances

    • Disruptions in homeostatic mechanisms controlling electrolyte levels.
    • Electrolyte imbalances are related to intake, output, absorption, and distribution of electrolytes in body fluids and their availability for use by body cells.

    Sodium Imbalance

    • Hypernatremia: Blood sodium > 145 mEq/L, caused by a relative deficit of water to salt in ECF
    • Hyponatremia: Blood sodium < 136 mEq/L, caused by excessive water in ECF Relative to Sodium

    Potassium Imbalance

    • Hyperkalemia: Blood potassium > 5.1 mEq/L, caused by increased intake or shift of potassium from ICF to blood
    • Hypokalemia: Blood potassium < 3.5 mEq/L, caused by fasting, low potassium intake or certain diuretics

    Calcium Imbalance

    • Hypercalcemia: Blood calcium > 10.5 mg/dL
    • Hypocalcemia: Blood calcium < 8.4 mg/dL

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    Description

    Explore the importance of fluid and electrolyte balance in the human body. This quiz covers body fluid volumes, compartments, sources of intake and output, and the regulation of bodily fluids. Test your knowledge on how these components support health and bodily functions.

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