Flonase (Fluticasone) RX Flashcards

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Questions and Answers

What is the generic name of Flonase?

Fluticasone

Which of the following are trade names for Fluticasone? (Select all that apply)

Ibuprofen

Flovent HFA (correct)

Arnuity Ellipta (correct)

Veramyst (correct)

What is the classification of Fluticasone?

Corticosteroid

Flonase dosage involves administering _ sprays initially then _ spray per nostril.

2, 1 Signup and view all the answers

What is the route of administration for Fluticasone?

Oral INH and Intranasal Signup and view all the answers

What is the time/frequency of using Flovent?

Bid (twice daily) Signup and view all the answers

What is the peak effect time for Fluticasone?

Several days Signup and view all the answers

What is the usual onset time for intranasal Fluticasone?

12 hours Signup and view all the answers

What is the duration of action for Fluticasone?

1-2 weeks Signup and view all the answers

What is the normal dosage range for Fluticasone?

100-500 mcg bid Signup and view all the answers

What lab alterations can be caused by this medication?

Unknown Signup and view all the answers

What are the uses of Fluticasone? (Select all that apply)

Prevention of chronic asthma (B), Nasal symptoms of rhinitis (D) Signup and view all the answers

How does Fluticasone act in the body?

Decreases inflammation by inhibiting mast cells, macrophages, and leukotrienes Signup and view all the answers

What should be assessed prior to administering Fluticasone?

Respiratory status and adrenal insufficiency Signup and view all the answers

What are reasons to hold Fluticasone administration?

Corticosteroid use Signup and view all the answers

What should be evaluated post-administration of Fluticasone?

Therapeutic response, decreased severity of asthma, COPD, allergies Signup and view all the answers

Which of the following are side effects of Fluticasone? (Select all that apply)

Diarrhea (A), Cough (B), Fatigue (D) Signup and view all the answers

Fluticasone is contraindicated in patients with hypersensitivity to milk protein.

True (A) Signup and view all the answers

What nursing considerations should be taken when administering Fluticasone?

Administer at 1-min intervals, give bronchodilator first if used Signup and view all the answers

What patient education should be provided regarding Fluticasone use?

Use bronchodilator first, do not use for acute asthma attacks Signup and view all the answers

What are some interactions with other drugs for Fluticasone? (Select all that apply)

Increased cardiac toxicity with isoproterenol (A), Increased fluticasone levels with CYP3A4 inhibitors (C) Signup and view all the answers

Study Notes

Fluticasone Overview

Generic Name: Fluticasone
Trade Names: Arnuity Ellipta, FLONASE, Flovent HFA, Flovent Diskus, Veramyst (nasal spray)
Classification: Corticosteroid

Dosage and Administration

Dosage for Flovent Diskus: 100 mcg twice a day (bid)
Dosage for Flonase: Start with 2 sprays, then 1 spray per nostril
Administration Routes: Oral inhalation (INH) and intranasal
Frequency: Flovent is taken bid, while Flonase is used daily

Pharmacokinetics

Peak Effects: Occur in several days
Onset of Action:
- Oral INH: 24 hours
- Intranasal: 12 hours
Duration of Action: 1-2 weeks
Normal Dosage Range: 100-500 mcg bid

Indications

Used for chronic asthma management during maintenance therapy, especially for patients requiring oral corticosteroids
Addresses nasal symptoms from seasonal/perennial allergies and nonallergic rhinitis
Unlabeled use includes Chronic Obstructive Pulmonary Disease (COPD)

Mechanism of Action

Acts by decreasing inflammation through inhibition of mast cells, macrophages, and leukotrienes
Possesses anti-inflammatory and vasoconstrictive properties

Nursing Considerations

Monitor for adrenal insufficiency and anaphylaxis
Conduct thorough respiratory assessments, including lung sounds and pulmonary function tests
Be vigilant for signs of adrenal insufficiency during the transition from systemic to inhalation corticosteroids, such as weakness, fatigue, and hypotension

Side Effects and Adverse Reactions

Common CNS effects: Fatigue, headache, dizziness
EENT effects: Pharyngitis, sinusitis, nasal discharge, and blurred vision
GI Effects: Diarrhea, abdominal pain, vomiting, risk of oral candidiasis
Metabolic effects: Hyperglycemia, growth retardation in children, Cushingoid features
Miscellaneous: Increased risk of infections, angioedema, potential for osteoporosis

Contraindications

Hypersensitivity to fluticasone or milk protein
Not advisable as primary treatment for status asthmaticus or acute bronchospasm
Caution in pregnancy, breastfeeding, and in patients with active infections or Cushing syndrome

Patient Education

Instruct patients to use bronchodilator first before corticosteroid inhalation
Emphasize that it is not for acute asthmatic attacks
Advise against smoking and exposure to secondhand smoke or individuals with respiratory infections
Encourage proper oral hygiene to prevent oral candidiasis

Drug Interactions

Use with caution when combined with CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) as these medications may increase fluticasone levels
Isoproterenol may increase cardiac toxicity in asthma patients

Post-Administration Assessment

Evaluate therapeutic response by monitoring asthma, COPD symptoms, and allergy severity
Look for any adverse reactions and adjust therapy as needed

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Description

Test your knowledge of Flonase, also known as Fluticasone, with these flashcards. Covering definitions, trade names, classification, dosing, and routes of administration, this quiz is perfect for pharmacy students or anyone seeking to learn more about this medication.