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Questions and Answers
What is the generic name of Flonase?
Fluticasone
Which of the following are trade names for Fluticasone? (Select all that apply)
What is the classification of Fluticasone?
Corticosteroid
Flonase dosage involves administering _______ sprays initially then _______ spray per nostril.
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What is the route of administration for Fluticasone?
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What is the time/frequency of using Flovent?
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What is the peak effect time for Fluticasone?
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What is the usual onset time for intranasal Fluticasone?
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What is the duration of action for Fluticasone?
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What is the normal dosage range for Fluticasone?
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What lab alterations can be caused by this medication?
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What are the uses of Fluticasone? (Select all that apply)
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How does Fluticasone act in the body?
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What should be assessed prior to administering Fluticasone?
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What are reasons to hold Fluticasone administration?
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What should be evaluated post-administration of Fluticasone?
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Which of the following are side effects of Fluticasone? (Select all that apply)
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Fluticasone is contraindicated in patients with hypersensitivity to milk protein.
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What nursing considerations should be taken when administering Fluticasone?
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What patient education should be provided regarding Fluticasone use?
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What are some interactions with other drugs for Fluticasone? (Select all that apply)
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Study Notes
Fluticasone Overview
- Generic Name: Fluticasone
- Trade Names: Arnuity Ellipta, FLONASE, Flovent HFA, Flovent Diskus, Veramyst (nasal spray)
- Classification: Corticosteroid
Dosage and Administration
- Dosage for Flovent Diskus: 100 mcg twice a day (bid)
- Dosage for Flonase: Start with 2 sprays, then 1 spray per nostril
- Administration Routes: Oral inhalation (INH) and intranasal
- Frequency: Flovent is taken bid, while Flonase is used daily
Pharmacokinetics
- Peak Effects: Occur in several days
- Onset of Action:
- Oral INH: 24 hours
- Intranasal: 12 hours
- Duration of Action: 1-2 weeks
- Normal Dosage Range: 100-500 mcg bid
Indications
- Used for chronic asthma management during maintenance therapy, especially for patients requiring oral corticosteroids
- Addresses nasal symptoms from seasonal/perennial allergies and nonallergic rhinitis
- Unlabeled use includes Chronic Obstructive Pulmonary Disease (COPD)
Mechanism of Action
- Acts by decreasing inflammation through inhibition of mast cells, macrophages, and leukotrienes
- Possesses anti-inflammatory and vasoconstrictive properties
Nursing Considerations
- Monitor for adrenal insufficiency and anaphylaxis
- Conduct thorough respiratory assessments, including lung sounds and pulmonary function tests
- Be vigilant for signs of adrenal insufficiency during the transition from systemic to inhalation corticosteroids, such as weakness, fatigue, and hypotension
Side Effects and Adverse Reactions
- Common CNS effects: Fatigue, headache, dizziness
- EENT effects: Pharyngitis, sinusitis, nasal discharge, and blurred vision
- GI Effects: Diarrhea, abdominal pain, vomiting, risk of oral candidiasis
- Metabolic effects: Hyperglycemia, growth retardation in children, Cushingoid features
- Miscellaneous: Increased risk of infections, angioedema, potential for osteoporosis
Contraindications
- Hypersensitivity to fluticasone or milk protein
- Not advisable as primary treatment for status asthmaticus or acute bronchospasm
- Caution in pregnancy, breastfeeding, and in patients with active infections or Cushing syndrome
Patient Education
- Instruct patients to use bronchodilator first before corticosteroid inhalation
- Emphasize that it is not for acute asthmatic attacks
- Advise against smoking and exposure to secondhand smoke or individuals with respiratory infections
- Encourage proper oral hygiene to prevent oral candidiasis
Drug Interactions
- Use with caution when combined with CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) as these medications may increase fluticasone levels
- Isoproterenol may increase cardiac toxicity in asthma patients
Post-Administration Assessment
- Evaluate therapeutic response by monitoring asthma, COPD symptoms, and allergy severity
- Look for any adverse reactions and adjust therapy as needed
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Description
Test your knowledge of Flonase, also known as Fluticasone, with these flashcards. Covering definitions, trade names, classification, dosing, and routes of administration, this quiz is perfect for pharmacy students or anyone seeking to learn more about this medication.
