Pharm - Pain
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Questions and Answers

What are first line recommendations for patients experiencing MILD acute pain?

  • Corticosteroids
  • Acetaminophen, NSAIDS, and RICE (correct)
  • Opioids
  • Manipulations
  • What is the first line recommendation for patients experiencing MODERATE to SEVERE acute pain?

  • NSAIDS and RICE
  • Corticosteroids
  • Opioids (correct)
  • Acetaminophen
  • In the management of chronic pain, opioids are indicates as a first line treatment.

    False

    When it comes to Chronic pain management, continue therapy only if there is clinically meaningful improvement in pain and function.

    <p>True</p> Signup and view all the answers

    Nonopioid therapies are at LEAST as effective as opioids for many common types of acute pain.

    <p>True</p> Signup and view all the answers

    Before prescribing opioid therapy for acute pain, clinicians should discuss with patients the realistic benefits and known risks of opioid therapy.

    <p>True</p> Signup and view all the answers

    For acute pain management, use longer acting immediate release opioids if opioid are indicated for the patient.

    <p>False</p> Signup and view all the answers

    What are examples of rehabilitative non-pharmaceutical therapies that can be used for patients?

    <p>Physical and occupational therapy</p> Signup and view all the answers

    What are examples of psychological non-pharmaceutical therapies that can be used for patients?

    <p>Cognitive-behavioral therapy</p> Signup and view all the answers

    What are examples of interventional non-pharmaceutical therapies that can be used for patients?

    <p>Surgical, Implant therapies, Neural blockade or Injection therapies</p> Signup and view all the answers

    What are examples of Complementary and Alternative non-pharmaceutical therapies that can be used for patients?

    <p>Chiropractic and Osteopathic</p> Signup and view all the answers

    Sickle cell crisis or acute pancreatitis patients are candidates for short term opioid use.

    <p>True</p> Signup and view all the answers

    What receptor do opioids work on?

    <p>Mu</p> Signup and view all the answers

    What is the GOLD standard opioid?

    <p>Morphine</p> Signup and view all the answers

    Morphine is a CNS depressant

    <p>True</p> Signup and view all the answers

    What patient should avoid oxycodone?

    <p>Hepatic Dysfunction</p> Signup and view all the answers

    Hydromorphone is __x more potent than morphine. It is a good agent for digestive pain.

    <p>4</p> Signup and view all the answers

    What opioid contains acetaminophen?

    <p>Hydrocodone</p> Signup and view all the answers

    What opioid has an immediate onset but is VERY potent? It also functions as a Serotonergic (serotonin syndrome).

    <p>Fentanyl</p> Signup and view all the answers

    What opioid may be use to augment therapy, but is also serotonergic?

    <p>Tramadol</p> Signup and view all the answers

    What more minor opioid can be prescribed and works additionally as a cough suppressant?

    <p>Codeine</p> Signup and view all the answers

    You should always prescribe NARCAN to any patients that are being prescribed an opioid.

    <p>True</p> Signup and view all the answers

    What tool should be administered to patients upon an initial visit prior to beginning opioid therapy for pain management?

    <p>Opioid Risk tool</p> Signup and view all the answers

    What opioid would you use for a patient with renal dysfunction, patients taking too many tablets, unbearable side effects of high dose opioids?

    <p>Hydromorphone</p> Signup and view all the answers

    What opioid agent can be used for moderate to severe pain but has a ceiling effect that decreases the risk of CNS depression?

    <p>Buprenorphine</p> Signup and view all the answers

    ALL opioids have the same MME (morphine mg equivalence)

    <p>False</p> Signup and view all the answers

    How do you calculate equianalgesic doses for opioids?

    <p>determine total daily dose, convert to MME with converting agent, determine MME to agent being changed to, and reduce dose by 50% for DAILY dose of new agent</p> Signup and view all the answers

    Avoid prescribing opioids and benzodiazepines concurrently

    <p>True</p> Signup and view all the answers

    You should review patient’s history of controlled substance prescriptions using state prescription drug monitoring program (PMP) before starting a opioid

    <p>True</p> Signup and view all the answers

    The lowest starting dose for opioid-naïve patients is

    <p>20–30 MME/ day</p> Signup and view all the answers

    ___ day for Acute/ 7-day surg, ___day for chronic pain, ____ day reviewed by DO/MD

    <p>5, 30, 90</p> Signup and view all the answers

    When patients have been taking opioids for longer durations (e.g., for ≥1 year), tapers of ____% per month or slower are likely to be better tolerated than more rapid tapers.

    <p>10</p> Signup and view all the answers

    What is the max dose for acetaminophen?

    <p>3-4 gm daily</p> Signup and view all the answers

    How are drugs classified?

    <p>Schedule 1 = Drugs with no currently accepted medical use and a high potential for abuse. They are the most dangerous drugs of all the drug schedules with potentially severe psychological or physical dependence. Schedule 2 = Drugs with a high potential for abuse, with use potentially leading to severe psychological or physical dependence. Schedule 3 = Drugs with a moderate to low potential for physical and psychological dependence. Schedule 5 = Drugs with lower potential for abuse than Schedule 4 and consist of preparations containing limited quantities of certain narcotics. Schedule 5 drugs are generally used for antidiarrheal, antitussive, and analgesic purposes.</p> Signup and view all the answers

    Ketamine is only indicated for in-patient treatment

    <p>True</p> Signup and view all the answers

    What types of drug can be used for purposes such as mild to moderate pain management, osteoarthritis, rheumatoid arthritis, gout, cardiovascular disease prevention, post-stent care, colorectal cancer risk reduction, migraine relief, pericarditis treatment, polycythemia vera prevention, preeclampsia management, valvular disease management, thromboembolism prevention, and arthroplasty prevention?

    <p>ASPIRIN</p> Signup and view all the answers

    Which drug profiles may be suitable candidates for aspirin in managing moderate to severe acute pain, addressing conditions such as opioid pain, migraines, post-operative cataracts, corneal refractive surgeries, and seasonal allergic conjunctivitis?

    <p>KETOROLAC</p> Signup and view all the answers

    What pain medication should not be used for patients with sulfa allergies?

    <p>CELECOXIB</p> Signup and view all the answers

    NSAIDS have an increased risk of CVA

    <p>True</p> Signup and view all the answers

    What drug can be used for managing diabetic neuropathy, post-herpetic neuralgia, chronic neuropathic pain, fibromyalgia, cough, restless leg syndrome, seizures, generalized anxiety disorder (GAD), social anxiety disorder (SAD), vasomotor symptoms of menopause, and pruritus?

    <p>GABAPENTIN</p> Signup and view all the answers

    What medication addressing conditions like diabetic peripheral neuropathy, post-herpetic neuralgia, fibromyalgia, osteoarthritis, and chronic pain management?

    <p>ANTIDEPRESSANTS like Cymbalta</p> Signup and view all the answers

    What can be used as adjunct therapy for acute musculoskeletal conditions?

    <p>ANTISPASMODICS</p> Signup and view all the answers

    What can acetaminophen cause in the long-term?

    <p>Liver damage</p> Signup and view all the answers

    Study Notes

    Acute Pain Management

    • For mild acute pain, first-line recommendation is nonopioid therapy.
    • For moderate to severe acute pain, first-line recommendation is not opioids.
    • Nonopioid therapies are at least as effective as opioids for many common types of acute pain.
    • Before prescribing opioid therapy, clinicians should discuss realistic benefits and known risks with patients.
    • For acute pain management, use longer acting immediate release opioids if opioid is indicated.

    Chronic Pain Management

    • Opioids are not indicated as a first-line treatment for chronic pain.
    • Continue therapy only if there is clinically meaningful improvement in pain and function.

    Non-Pharmaceutical Therapies

    • Examples of rehabilitative therapies:
    • Examples of psychological therapies:
    • Examples of interventional therapies:
    • Examples of Complementary and Alternative therapies:

    Opioids

    • Opioids work on the mu receptor.
    • Morphine is the gold standard opioid and a CNS depressant.
    • Hydromorphone is 2-4 times more potent than morphine and is a good agent for digestive pain.
    • Percocet contains acetaminophen.
    • Fentanyl has an immediate onset but is very potent and also functions as a Serotonergic (serotonin syndrome).
    • Methadone may be used to augment therapy but is also serotonergic.
    • Codeine is a more minor opioid that can be prescribed and works additionally as a cough suppressant.
    • NARCAN should always be prescribed to patients being prescribed an opioid.
    • The tool that should be administered to patients upon an initial visit prior to beginning opioid therapy is the Opioid Risk Tool (ORT).

    Safe Opioid Prescribing

    • When patients have been taking opioids for longer durations (e.g., for ≥1 year), tapers of 10% per month or slower are likely to be better tolerated than more rapid tapers.
    • Avoid prescribing opioids and benzodiazepines concurrently.
    • Review patient’s history of controlled substance prescriptions using state prescription drug monitoring program (PMP) before starting a opioid.
    • The lowest starting dose for opioid-naïve patients is 3-day for Acute/ 7-day surgical, 7-day for chronic pain, and 7-day reviewed by DO/MD.

    Other Medications

    • The maximum dose for acetaminophen is 3,000 mg/day.
    • Drugs are classified by their mechanism of action.
    • Ketamine is only indicated for in-patient treatment.
    • NSAIDS have an increased risk of CVA and are suitable for purposes such as mild to moderate pain management, osteoarthritis, rheumatoid arthritis, and more.
    • Aspirin is suitable for managing moderate to severe acute pain, addressing conditions such as opioid pain, migraines, and more.
    • Sulfa allergic patients should not use sulfonamide-containing medications like celecoxib.
    • Gabapentin can be used for managing diabetic neuropathy, post-herpetic neuralgia, chronic neuropathic pain, and more.
    • Duloxetine can be used for addressing conditions like diabetic peripheral neuropathy, post-herpetic neuralgia, fibromyalgia, and osteoarthritis.
    • Cyclobenzaprine can be used as adjunct therapy for acute musculoskeletal conditions.
    • Long-term use of acetaminophen can cause liver damage.

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    Description

    This quiz covers the initial steps healthcare providers recommend for patients experiencing sudden onset of pain. Test your knowledge on the immediate actions to take for managing acute pain.

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