Clarification and Filtration
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Questions and Answers

Which material is preferred for most liquid filtration due to its chemical inertness and ability to withstand high temperatures?

  • Nylon
  • Stainless steel
  • Teflon (correct)
  • Cotton

What is a primary characteristic of felts used as filter media?

  • Low strength
  • High flow rate with low pressure drop (correct)
  • High pressure drop
  • Low flow rate

Which type of filter media provides good surfaces for cake filtration and is often used with filter aids?

  • Woven wire cloth (correct)
  • Non-woven filter media
  • Monofilament nylon cloth
  • Wire mesh filters

Which material is suitable for coarse straining in aseptic filtrations and is available for openings as small as 10 μm?

<p>Nylon (B)</p> Signup and view all the answers

Why are wire screens particularly recommended as support elements for disposable media?

<p>High resistance to plugging (D)</p> Signup and view all the answers

What types of materials are included in non-woven filter media besides felts?

<p>Bonded fabrics and kraft papers (B)</p> Signup and view all the answers

What factor influences the rate of filtration in cake filtration?

<p>Volume of the filter cake solids per unit volume of filtrate (C)</p> Signup and view all the answers

What happens when the filter medium becomes plugged or slimy with the accumulation of solids?

<p>The flow of filtrate stops (A)</p> Signup and view all the answers

What role does a filter aid play in the filtration process?

<p>It screens out all solids, preventing them from plugging the filter medium (C)</p> Signup and view all the answers

How does a higher concentration of solids in a suspension affect the void space in cake filtration?

<p>Leads to bridging over of openings in the void space (C)</p> Signup and view all the answers

How can the duration of a filtration cycle and clarity attained be controlled?

<p>By adjusting the quantity, type, and particle size of the filter aid (A)</p> Signup and view all the answers

What effect does poorly flocculated solids have on resistance in filtration compared to other solids?

<p>They offer higher resistance due to lower porosity (B)</p> Signup and view all the answers

What is the main feature of a disc filter?

<p>Less floor space and low filtration cost (D)</p> Signup and view all the answers

What influences the filtration rate in pressure filters?

<p>Coarser particles and increased pressure (D)</p> Signup and view all the answers

In what situations are plate and frame filter presses mainly used?

<p>When the added value to the product is high (A)</p> Signup and view all the answers

What is the main objective when a plate and frame filter press is operated in 'batch' mode?

<p>Enhancing the clarity of the fluid (B)</p> Signup and view all the answers

What does a plate and frame filter press assembly consist of?

<p>Solid frames supporting filter media (B)</p> Signup and view all the answers

Why are continuous filters less commonly used despite their availability?

<p>Mechanical complexity and high cost due to cake removal difficulty (B)</p> Signup and view all the answers

What is commonly used with funnels for gravity filtration in laboratories?

<p>Filter paper (B)</p> Signup and view all the answers

Which type of filters are greatly utilized in laboratory settings?

<p>Suction filters (A)</p> Signup and view all the answers

What type of filter bags are used in laboratory settings for gravity filtration?

<p>Fabric bags (C)</p> Signup and view all the answers

What is the most common medium for laboratory filtrations?

<p>Circular filter papers (A)</p> Signup and view all the answers

What restricts the use of glass beads or sand as gravity filters for certain operations in the laboratory?

<p>Uncertainty of adequate clarification (C)</p> Signup and view all the answers

What is generally used for small-scale laboratory operations and also known as filter sticks?

<p>Immersion filter tubes (C)</p> Signup and view all the answers

What is the primary principle behind ultrafiltration?

<p>Selective molecular separation based on size (D)</p> Signup and view all the answers

How does ultrafiltration differ from microfiltration?

<p>Ultrafiltration removes dissolved molecules based on size; microfiltration removes particulates and bacteria. (A)</p> Signup and view all the answers

How can a membrane be selected to achieve the separation of a solvent and a solute?

<p>By allowing the solvent but not the solute to pass through (C)</p> Signup and view all the answers

How are two solutes of different molecular sizes separated using ultrafiltration?

<p>Choosing a membrane that allows the smaller molecule to pass through but holds back the larger one (A)</p> Signup and view all the answers

How are the selectivity and retentivity of a membrane characterized?

<p>By its molecular weight cut off (D)</p> Signup and view all the answers

What is a significant application of ultrafiltration in the pharmaceutical industry?

<p>Concentration of heat-labile products (D)</p> Signup and view all the answers

What factor is considered when selecting the pore size for a filter medium in sterilizing filtration?

<p>The largest particle to be removed (A)</p> Signup and view all the answers

For a liquid with viscosity different from water, how is the initial flow rate estimation calculated?

<p>The viscosity is divided by the flow rate of clean water (D)</p> Signup and view all the answers

What is advised to ensure compatibility in filter selection with the liquid or gas to be filtered?

<p>Checking chemical compatibility charts provided by vendors (B)</p> Signup and view all the answers

What is the main consideration in achieving a balance between filter media and equipment capabilities according to the text?

<p>Slurry characteristics and quality specifications (B)</p> Signup and view all the answers

Why must a balance be achieved between filter media and equipment capabilities?

<p>To meet a broad span of pharmaceutical requirements (C)</p> Signup and view all the answers

In what type of filtration is a plate and frame filter or wovenfiber filter suitable according to the text?

<p>Clarification filtration (B)</p> Signup and view all the answers

What determines the required filtration surface area after establishing filter media, pore size, flow rate, and pressure differentials?

<p>The size of the particles to be removed (A)</p> Signup and view all the answers

What type of filtration requires selecting a pore size smaller than the smallest particle to be removed?

<p>Sterilizing filtration (B)</p> Signup and view all the answers

Which filtration process often employs a 0.2 μm pore size for effective operation?

<p>Ultrafiltration (A)</p> Signup and view all the answers

What aspect influences the choice between surface and depth filtration principles in batch pressure filters?

<p>The slurry characteristics and final product quality specifications (A)</p> Signup and view all the answers

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