Factors Influencing Enzyme Reaction Velocity
30 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which of the following best defines enzyme kinetics?

  • The study of how enzymes are inhibited by drugs
  • The study of chemical reactions that are catalyzed by enzymes (correct)
  • The study of how enzymes work
  • The study of how enzymes control metabolism

What does the Michaelis-Menten equation describe?

  • How enzyme kinetics vary with substrate concentration (correct)
  • How enzyme activity is controlled
  • How enzyme inhibitors work
  • How enzymes form ES complexes

Who were the scientists behind the Michaelis-Menten equation?

  • Enzymes Part 2
  • Leonor Michaelis and Maud Menten (correct)
  • Clara Camargo and DVM
  • Carnotcycle WordPress

What is the Lineweaver-Burk plot used for?

<p>To interpret 1/Vmax and 1/Km (A)</p> Signup and view all the answers

What are the two types of enzyme inhibition?

<p>Competitive and noncompetitive (B)</p> Signup and view all the answers

How can competitive and noncompetitive inhibitors be explained using the Michaelis-Menten curve and Lineweaver-Burk plot?

<p>By interpreting 1/Vmax and 1/Km values (A)</p> Signup and view all the answers

What is an example of an enzyme inhibitor?

<p>Drugs (B)</p> Signup and view all the answers

Which factor affects the rate of an enzyme-catalyzed reaction until a maximal velocity is reached?

<p>Substrate concentration (A)</p> Signup and view all the answers

What happens to the reaction velocity when the temperature is further elevated beyond the optimal temperature for most mammalian enzymes?

<p>It decreases (C)</p> Signup and view all the answers

How does extreme pH conditions affect the reaction velocity of enzymes?

<p>It decreases the reaction velocity (D)</p> Signup and view all the answers

What is the effect of a competitive inhibitor on the Vmax of an enzyme-catalyzed reaction?

<p>It has no effect on Vmax (C)</p> Signup and view all the answers

How does a competitive inhibitor affect the Km for a given substrate?

<p>It increases Km (A)</p> Signup and view all the answers

What is the effect of a competitive inhibitor on the Lineweaver-Burk plot?

<p>Vmax is unchanged (D)</p> Signup and view all the answers

What is the effect of irreversible inhibitors on enzymes?

<p>They denature enzymes (A)</p> Signup and view all the answers

Which of the following is true about the Michaelis-Menten kinetics?

<p>Km is equal to the substrate concentration at which the reaction velocity is ½ Vmax (A)</p> Signup and view all the answers

Which of the following conclusions can be drawn from the Michaelis-Menten equation?

<p>Enzyme 1 has a high affinity for its substrate because a low concentration of substrate is needed to half-saturate the enzyme (A)</p> Signup and view all the answers

Which of the following statements is true about the oxyhemoglobin dissociation curve?

<p>It shows a sigmoidal curve (B)</p> Signup and view all the answers

Which type of kinetics do allosteric enzymes exhibit?

<p>Sigmoidal curve (A)</p> Signup and view all the answers

Which of the following is true about the Lineweaver-Burk plot?

<p>It is used to calculate Km and Vmax (A)</p> Signup and view all the answers

Which order of reaction is observed when [S] << Km?

<p>Zero order (D)</p> Signup and view all the answers

Which of the following is true about the total enzyme concentration [E] in the Michaelis-Menten kinetics?

<p>It does not change over time (A)</p> Signup and view all the answers

Which enzyme do statin drugs inhibit?

<p>Cholesterol biosynthesis hydroxymethylglutaryl-CoA reductase (A)</p> Signup and view all the answers

What is the mechanism of action of statin drugs?

<p>Prevent de novo cholesterol synthesis (D)</p> Signup and view all the answers

Where do noncompetitive inhibitors bind?

<p>Allosteric site (A)</p> Signup and view all the answers

What is the effect of noncompetitive inhibitors on Vmax?

<p>Decrease Vmax (B)</p> Signup and view all the answers

What is the effect of noncompetitive inhibitors on Km?

<p>Km remains unchanged (B)</p> Signup and view all the answers

Which type of inhibitors bind at a site different from the substrate?

<p>Noncompetitive inhibitors (A)</p> Signup and view all the answers

What is the main target of β-lactam antibiotics?

<p>Enzymes important for bacterial cell wall synthesis (A)</p> Signup and view all the answers

What is the mechanism of action of ACE inhibitors?

<p>Block the enzyme that cleaves angiotensin I to angiotensin II (C)</p> Signup and view all the answers

What does aspirin irreversibly inhibit?

<p>Prostaglandin and thromboxane synthesis (C)</p> Signup and view all the answers

More Like This

Factors Influencing Flexibility Quiz
10 questions
Enzyme Action and Influencing Factors
37 questions
Enzyme Activity and Factors Influencing It
41 questions
Use Quizgecko on...
Browser
Browser