Factors Affecting Wound Healing Quiz

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Questions and Answers

Which type of wound involves non-traumatic wounds with contaminated entry into a viscus, but with minimal spillage?

Clean contaminated

What type of wound includes traumatic wounds or significant spillage from a viscus or acute inflammation?

Contaminated

Which type of wound includes non-traumatic wounds with no septic focus and no viscus opened?

Clean

What type of wound includes traumatic wounds from a dirty source or significant bacterial contamination or release of pus?

Dirty Signup and view all the answers

Which of the following statements about viral endotoxin is true?

It is a lipopolysaccharide present on the cell surface Signup and view all the answers

How is injury-induced vascular leakage related to endothelial retractions?

Leakage leads to retraction of the endothelial lining of blood vessels Signup and view all the answers

What are the consequences of recurrent attacks of acute inflammation?

They can lead to the development of chronic inflammatory reactions Signup and view all the answers

How does streptococcal tonsillitis affect neutrophil count?

It is associated with an increase in neutrophil count Signup and view all the answers

Which cells have no capacity to regenerate?

Permanent cells Signup and view all the answers

What is granulation tissue composed of?

Capillary loops and myofibroblasts Signup and view all the answers

Which stage of wound healing involves fibroblasts synthesizing collagen and causing wound contraction?

Proliferation Signup and view all the answers

What mediates wound contraction, reducing tissue defects and forming a scar?

Myofibroblasts Signup and view all the answers

Which cells are responsible for secreting collagen to form a scar?

Fibroblasts Signup and view all the answers

What is the primary component involved in increasing wound strength during wound healing?

Collagen fibers Signup and view all the answers

Which factor does not affect wound healing?

High humidity Signup and view all the answers

What characterizes the initial stage of a scar?

Flat and pale Signup and view all the answers

In whom do scars take longer to settle and improve?

Infants Signup and view all the answers

What distinguishes keloid scars from hypertrophic scars?

They extend beyond wound boundaries Signup and view all the answers

What causes stretched scars?

Dehiscence of the dermis under intact epidermis Signup and view all the answers

What are adhesion scars?

Bands of scar tissue binding normally unjoined tissue Signup and view all the answers

When do scar contractures commonly occur?

After secondary intention healing Signup and view all the answers

What is the effect of infection on the scarring process?

It makes scars more pronounced Signup and view all the answers

What is a possible consequence of impaired arterial supply on wound healing?

Delayed wound closure Signup and view all the answers

How do metabolic disorders affect wound healing?

They increase the risk of keloid formation Signup and view all the answers

Study Notes

Wound healing involves the reorientation and maturation of collagen fibers, increasing wound strength and leading to a flat, pale, slightly shiny scar. This process takes 3 weeks to 1 year.
Wound healing can be affected by various factors, including impaired arterial supply or venous drainage (global or local), age of the patient, excessive movement or distension, infection, malignancy, foreign body, necrotic tissue, smoking, malnutrition, immunosuppression, anticancer therapies, and metabolic disorders.
A scar is an area of fibrous connective tissue produced by healing. It is initially flat and pale, then becomes red, itchy, and raised before settling back to a flat, pale, slightly shiny patch. The scarring process is more pronounced if infection intervenes during healing or in the presence of foreign bodies.
Children's scars take longer to settle and improve over 2-3 years, but they resolve rapidly in the elderly.
Three types of abnormal scars exist: hypertrophic scars, which are firm, red, itchy, and elevated above the skin surface but within wound boundaries; keloid scars, which extend beyond wound boundaries and do not regress spontaneously; and stretched scars, which are caused by the dehiscence of the dermis under intact epidermis and are common on the back and abdomen.
Adhesion scars are bands of scar tissue that bind normally unjoined tissue. They can appear as thin sheets of tissue or thick fibrous bands. Adhesions form when the dermis under the intact epidermis separates.
Scar contractures are common on the flexor surfaces of joints. They occur when wounds heal by secondary intention, after split skin grafting, or when incisions cross a joint perpendicular to the crease.

Key facts from text:

Wound healing involves the reorientation and maturation of collagen fibers, increasing wound strength.
Wound healing can be affected by various factors like impaired arterial supply, age of patient, excessive movement, infection, and malnutrition.
Scars are made of fibrous connective tissue produced during healing.
Children's scars take longer to settle and improve.
Three types of abnormal scars are hypertrophic, keloid, and stretched scars.
Adhesion scars are bands of scar tissue that bind normally unjoined tissue.
Scar contractures are common on the flexor surfaces of joints.