Factors Affecting Drug Metabolism
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Questions and Answers

Which factor affects the action of drugs at higher altitudes?

  • Racial differences
  • Low metabolism (correct)
  • High humidity
  • Slow disintegration of solid drugs

In which climate do purgatives act better according to the text?

  • Cold and humid
  • Hot and dry
  • Hot and humid (correct)
  • Cold and dry

What happens to the action of outdated tetracyclines?

  • Increased effectiveness
  • No change in action
  • Reduced toxicity
  • Excretion of amino acids in urine (correct)

In what form do drugs show rapid onset of action according to the text?

<p>Liquid form (B)</p> Signup and view all the answers

Which factor can affect drug absorption by causing decreased binding sites for drugs?

<p>Malnutrition (B)</p> Signup and view all the answers

For which condition is it important to consider drug excretion through breast milk?

<p>Lactation (A)</p> Signup and view all the answers

In which situation are drugs better absorbed in an empty stomach?

<p>Food (D)</p> Signup and view all the answers

Which factor affects drug dosage as it is given per kg of this measure?

<p>Body weight (B)</p> Signup and view all the answers

Which physiological response to a drug can lead to skin rashes, urticaria, and bronchoconstriction?

<p>Allergy (A)</p> Signup and view all the answers

Study Notes

Factors Affecting Drug Action

  • Higher altitude affects the action of drugs due to lower oxygen levels.
  • Purgatives act better in hot and humid climate.

Drug Absorption and Action

  • Outdated tetracyclines can cause kidney damage.
  • Drugs in the lipophilic form show rapid onset of action.

Factors Affecting Drug Absorption

  • Gastritis can affect drug absorption by causing decreased binding sites for drugs.

Drug Administration and Excretion

  • It's important to consider drug excretion through breast milk for lactating women.
  • Some drugs are better absorbed in an empty stomach.

Drug Dosage

  • Drug dosage is affected by body surface area, as it is given per kg of body surface area.

Adverse Drug Reactions

  • Histamine release, a physiological response to a drug, can lead to skin rashes, urticaria, and bronchoconstriction.

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Test your knowledge of how environmental factors, climate, racial differences, and drug preparation can influence drug metabolism and effectiveness in this pharmacology quiz.

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