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Ezetimibe in Monotherapy and Combined Use

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Ezetimibe in Monotherapy and Combined Use

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Questions and Answers

Which of the following is NOT mentioned as a possible side effect of Ezetimibe?

Myopathy

Rhabdomyolysis

Hepatitis

Constipation (correct)

What is a reported adverse effect of Bempedoic Acid?

Nausea

Headache

Tendon rupture (correct)

Constipation

In patients taking a statin, adding ezetimibe slightly increases the risk for which condition?

Liver damage (correct)

Heart attack

Lung infection

Kidney damage

What is a potential side effect of Bempedoic Acid/Ezetimibe combination drug?

Myalgia (C) Signup and view all the answers

Which drug is specifically recommended for patients with true statin intolerance?

Bempedoic Acid (C) Signup and view all the answers

Which cholesterol medication can raise HDL cholesterol but has little or no effect on LDL cholesterol?

Fibrates (D) Signup and view all the answers

What is the principal indication for gemfibrozil?

Decreasing plasma TG content (C) Signup and view all the answers

How does gemfibrozil affect LDL levels in patients with high TG levels?

It increases LDL levels (A) Signup and view all the answers

What common side effect is associated with gemfibrozil use?

Gallstones (A) Signup and view all the answers

How do PCSK9 inhibitors work to reduce LDL cholesterol?

By increasing LDL receptor activity (A) Signup and view all the answers

What is a potential risk associated with PCSK9 inhibitors due to their protein composition?

Antibody development (C) Signup and view all the answers

What class of drugs are alirocumab and evolocumab categorized under?

PCSK9 inhibitors (C) Signup and view all the answers

In what patients are PCSK9 inhibitors indicated for use?

Patients needing additional LDL lowering (C) Signup and view all the answers

What is the role of PCSK9 in relation to LDL receptors?

It decreases the number of LDL receptors (B) Signup and view all the answers

Which reaction has been noted as a potential hypersensitivity reaction to PCSK9 inhibitors?

Vasculitis (D) Signup and view all the answers

Why should warfarin dosage be adjusted when taking gemfibrozil?

Gemfibrozil displaces warfarin from plasma albumin (A) Signup and view all the answers

What type of angina will the lecture focus on?

Chronic stable angina (B) Signup and view all the answers