Extracellular Matrix Overview

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Which glycosaminoglycan is found in high amounts in the extracellular matrix of the central nervous system?

Heparin

Chondroitin sulfate (correct)

Keratan sulfate

Hyaluronic acid

What is the main function of proteoglycans in the extracellular matrix?

Serve as receptors for cell growth (correct)

Act as enzymes for matrix degradation

Participate in osmotic pressure regulation

Maintain bone mineralization

What is the main function of heparin among the glycosaminoglycans?

Bone mineralization

Cell growth regulation

Anticoagulant activity (correct)

Cell membrane formation

What is a common role of glycosaminoglycans like chondroitin sulfate and hyaluronic acid?

Facilitate cell migration Signup and view all the answers

Which glycosaminoglycan plays a critical role in corneal transparency?

Keratan sulfate Signup and view all the answers

Where is dermatan sulfate mainly found in the body?

Skin Signup and view all the answers

What is the primary role of keratan sulfate in the eye?

Contribute to corneal transparency Signup and view all the answers

Which glycosaminoglycan is involved in the prevention of nerve endings repair after injury?

Chondroitin sulfate Signup and view all the answers

What is a key function of heparan sulfate in the body?

Cell communication Signup and view all the answers

What is a characteristic function of glycosaminoglycans like hyaluronic acid and chondroitin sulfate?

Facilitate cell migration during wound repair Signup and view all the answers

What is the main role of fibronectin in the extracellular matrix?

Cell adhesion and migration Signup and view all the answers

Which of the following is NOT a characteristic of collagen triple helix structure?

Formation of hydroxyproline post-translationally Signup and view all the answers

How do proteoglycans contribute to the organization of the extracellular matrix?

By binding to fibronectin and laminin Signup and view all the answers

Which of the following is a characteristic feature of glycosaminoglycans (GAGs)?

Disaccharide composition Signup and view all the answers

What is the primary function of laminin in the extracellular matrix?

Cell adhesion and migration Signup and view all the answers

Which enzyme is responsible for the formation of hydroxylysine in collagen triple helix structure?

Lysyl hydroxylase Signup and view all the answers

In which type of collagen is hydroxyproline formed by post-translational modification?

Collagen type forming fibrils Signup and view all the answers