Extracellular Matrix Overview
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Questions and Answers

Which glycosaminoglycan is found in high amounts in the extracellular matrix of the central nervous system?

  • Heparin
  • Chondroitin sulfate (correct)
  • Keratan sulfate
  • Hyaluronic acid
  • What is the main function of proteoglycans in the extracellular matrix?

  • Serve as receptors for cell growth (correct)
  • Act as enzymes for matrix degradation
  • Participate in osmotic pressure regulation
  • Maintain bone mineralization
  • What is the main function of heparin among the glycosaminoglycans?

  • Bone mineralization
  • Cell growth regulation
  • Anticoagulant activity (correct)
  • Cell membrane formation
  • What is a common role of glycosaminoglycans like chondroitin sulfate and hyaluronic acid?

    <p>Facilitate cell migration</p> Signup and view all the answers

    Which glycosaminoglycan plays a critical role in corneal transparency?

    <p>Keratan sulfate</p> Signup and view all the answers

    Where is dermatan sulfate mainly found in the body?

    <p>Skin</p> Signup and view all the answers

    What is the primary role of keratan sulfate in the eye?

    <p>Contribute to corneal transparency</p> Signup and view all the answers

    Which glycosaminoglycan is involved in the prevention of nerve endings repair after injury?

    <p>Chondroitin sulfate</p> Signup and view all the answers

    What is a key function of heparan sulfate in the body?

    <p>Cell communication</p> Signup and view all the answers

    What is a characteristic function of glycosaminoglycans like hyaluronic acid and chondroitin sulfate?

    <p>Facilitate cell migration during wound repair</p> Signup and view all the answers

    What is the main role of fibronectin in the extracellular matrix?

    <p>Cell adhesion and migration</p> Signup and view all the answers

    Which of the following is NOT a characteristic of collagen triple helix structure?

    <p>Formation of hydroxyproline post-translationally</p> Signup and view all the answers

    How do proteoglycans contribute to the organization of the extracellular matrix?

    <p>By binding to fibronectin and laminin</p> Signup and view all the answers

    Which of the following is a characteristic feature of glycosaminoglycans (GAGs)?

    <p>Disaccharide composition</p> Signup and view all the answers

    What is the primary function of laminin in the extracellular matrix?

    <p>Cell adhesion and migration</p> Signup and view all the answers

    Which enzyme is responsible for the formation of hydroxylysine in collagen triple helix structure?

    <p>Lysyl hydroxylase</p> Signup and view all the answers

    In which type of collagen is hydroxyproline formed by post-translational modification?

    <p>Collagen type forming fibrils</p> Signup and view all the answers

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