Extracellular Matrix and Cartilage Quiz

<p>From blue to red or purple. (C)</p> Signup and view all the answers

<p>Ground substance matrix (D)</p> Signup and view all the answers

<p>Directly transporting nutrients through blood vessels. (A)</p> Signup and view all the answers

<p>The extensive extracellular matrix. (A)</p> Signup and view all the answers

<p>Avascular nature. (B)</p> Signup and view all the answers

<p>Glycosaminoglycans. (A)</p> Signup and view all the answers

<p>Proteoglycan aggregates (A)</p> Signup and view all the answers

<p>Found within lacunae. (A)</p> Signup and view all the answers

<p>Covering some cartilage types and facilitating appositional growth. (B)</p> Signup and view all the answers

<p>Cartilage does not have a direct blood supply, unlike most other connective tissues. (B)</p> Signup and view all the answers

<p>To act as a collagen receptor on chondrocytes and help them anchor to the matrix (A)</p> Signup and view all the answers

<p>Aggrecan (C)</p> Signup and view all the answers

<p>Chondrocyte cell death (D)</p> Signup and view all the answers

<p>Basophilia (B)</p> Signup and view all the answers

<p>Binding aggrecans and supporting them (B)</p> Signup and view all the answers

<p>To influence the interaction between chondrocytes and matrix molecules (B)</p> Signup and view all the answers

<p>Elastin (A)</p> Signup and view all the answers

<p>To serve as markers of cartilage turnover and degeneration (A)</p> Signup and view all the answers

<p>Territorial matrix (C)</p> Signup and view all the answers

<p>Newly divided cells (B)</p> Signup and view all the answers

<p>Basophilic cytoplasm and large Golgi apparatus (A)</p> Signup and view all the answers

<p>Interterritorial matrix (B)</p> Signup and view all the answers

<p>Active protein synthesis (C)</p> Signup and view all the answers

<p>Lipid droplets (B)</p> Signup and view all the answers

<p>Singularly or in clusters called isogenous groups (C)</p> Signup and view all the answers

<p>Less intense (A)</p> Signup and view all the answers

<p>Numerous rough endoplasmic reticulum (rER) (A)</p> Signup and view all the answers

<p>Type II (B)</p> Signup and view all the answers

<p>Chondrocytes (D)</p> Signup and view all the answers

<p>To facilitate nutrient diffusion and waste exchange (C)</p> Signup and view all the answers

<p>Interstitial growth (A)</p> Signup and view all the answers

<p>Mesenchymal tissue (B)</p> Signup and view all the answers

<p>Inner cellular layer (Chondrogenic layer) (B)</p> Signup and view all the answers

<p>Chondroblasts derived from perichondrium (A)</p> Signup and view all the answers

<p>Articular cartilage (A)</p> Signup and view all the answers

<p>Inner portion of the perichondrium (A)</p> Signup and view all the answers

<p>Articular cartilage (A)</p> Signup and view all the answers

<p>Degradation of the extracellular matrix (B)</p> Signup and view all the answers

<p>Growth within an existing cartilage mass (A)</p> Signup and view all the answers

<p>They occupy the same lacuna (C)</p> Signup and view all the answers

<p>Anastomosing elastic fibers (C)</p> Signup and view all the answers

<p>Intervertebral discs (D)</p> Signup and view all the answers

<p>SOX-9 expression (B)</p> Signup and view all the answers

<p>Dispersed among collagen fibers in rows, singly, or in isogenous groups (A)</p> Signup and view all the answers

The three types of cartilage are hyaline, elastic, and fibrocartilage.

A cell in cartilage that secretes the extracellular matrix.

Mature cartilage cell that maintains the cartilage matrix.

The connective tissue surrounding cartilage that supplies nutrients.

The process of cartilage development is called chondrogenesis.

Growth of cartilage from within, occurs in the matrix.

Growth of cartilage by addition of new layers from the outside.

Cartilage matrix consists of collagen fibers and ground substance (proteoglycans).

The varying levels of color intensity observed in tissue samples that indicate the presence of sulfated proteoglycans.

A dense ring of matrix surrounding chondrocytes, containing high concentrations of proteoglycans and type VI collagen.

The region of the extracellular matrix surrounding the chondrocytes, with a moderate concentration of matrix components.

Area between territorial matrices, containing lower concentrations of proteoglycans and other components.

Complex molecules that bind water and help maintain tissue structure, shifting colors in staining.

Glycoproteins that help anchor chondrocytes to the extracellular matrix in cartilage.

Main structural component of hyaline cartilage providing tensile strength and framework.

Proteoglycans in cartilage that bind water and resist swelling pressure.

Supports cartilage shape, tensile strength, and swelling resistance.

Staining property of the matrix due to negatively charged GAGs binding basic dyes.

Change in dye color when binding to certain components in the matrix.

Process that can lead to chondrocyte death and loss of cartilage function.

Clusters of newly divided chondrocytes that are formed together as they secrete matrix material.

Chondrocyte cytoplasm appearance changes based on activity; active ones are basophilic, indicating protein synthesis.

Indicates high protein synthesis activity in chondrocytes due to increased ribosome presence.

Less active chondrocytes containing glycogen and lipid droplets, often appearing as clear areas under a microscope.

Storage fat seen as clear areas within less active chondrocytes' cytoplasm.

Chondroblasts are cells that secrete the cartilage matrix and move apart during deposition.

Isogenic cell clusters are groups of chondrocytes that arise from the division of single chondrocytes in the matrix.

Chondrogenesis involves mesenchymal progenitor cells differentiating into chondroblasts and then to chondrocytes.

SOX-9 is a transcription factor that guides the differentiation of inner perichondrial cells into chondroblasts during appositional growth.

Chondrocytes secrete collagen, glycosaminoglycans, and glycoproteins.

The most numerous collagen type secreted by chondrocytes.

A layer of dense irregular connective tissue around cartilage.

The inner layer of perichondrium that produces new cartilage cells.

Hyaline cartilage covering synovial joint surfaces without perichondrium.

A degenerative disease affecting articular cartilage.

Cartilage containing elastin that grants elasticity.

Found in the ear, Eustachian tube, and epiglottis.

A mix of dense connective tissue and hyaline cartilage.

Chondrocytes are dispersed in rows or groups within collagen.