Podcast
Play an AI-generated podcast conversation about this lesson
Questions and Answers
Which cells migrate into B cell-rich follicles and are called follicular helper T (Tfh) cells?
Which cells migrate into B cell-rich follicles and are called follicular helper T (Tfh) cells?
- Memory B cells
- Germinal center cells
- CD4+ T cells (correct)
- Plasma cells
Which cytokine secreted by Tfh cells has an important but incompletely understood role in Tfh cell function?
Which cytokine secreted by Tfh cells has an important but incompletely understood role in Tfh cell function?
- Interleukin (IL)-21 (correct)
- Interleukin (IL)-17
- Interferon (IFN)-γ
- Interleukin (IL)-4
Where do most of the events in fully developed antibody responses occur?
Where do most of the events in fully developed antibody responses occur?
- Plasma cells
- Extra-follicular foci
- Lymphoid follicles
- Germinal centers (correct)
Which cells migrate back into the lymphoid follicle together with Tfh cells?
Which cells migrate back into the lymphoid follicle together with Tfh cells?
Signup and view all the answers
What is the doubling time of the proliferating B cells in the germinal center?
What is the doubling time of the proliferating B cells in the germinal center?
Signup and view all the answers
Where do B cells undergo extensive isotype switching and somatic mutation of Ig genes?
Where do B cells undergo extensive isotype switching and somatic mutation of Ig genes?
Signup and view all the answers
What happens to B cells with the highest-affinity Ig receptors in the germinal center?
What happens to B cells with the highest-affinity Ig receptors in the germinal center?
Signup and view all the answers
Flashcards are hidden until you start studying
