20 Questions
Which part of staphylococcus has a high affinity for the FC receptor on lgG molecules and complement?
Protein A
What is the function of Protein A?
To attach to the Fc receptor
What is the role of the FC portion of an antibody?
It attaches to the white blood cells
What is the function of Fab in an antibody?
To recognize antigens
Which strains of staphylococcus can produce virulence Gamma?
Staph epidermidis and staph haemolyticus
What is the function of Panton Valentine Leukocidin (PVL)?
To inhibit phagocytosis
What is the effect of Panton Valentine Leukocidin (PVL) on neutrophils?
It inhibits phagocytosis
What can be seen in coagulation negative staphylococcus?
Gamma
What is the function of coagglutination in the laboratory?
To produce coagglutination
What happens to the granules inside neutrophils when Panton Valentine Leukocidin (PVL) is present?
They are released
Which type of coagulase is located at the cell wall surface and binds nonenzymatically to fibrinogen and platelets, leading to aggregation of the bacteria?
Bound coagulase
Which type of coagulase is detected using the slide coagulase test and may coat neutrophils, preventing phagocytosis?
Alpha coagulase
Which type of coagulase is detected by the tube coagulase test and activates the differentiation of prothrombin to thrombin?
Free coagulase
Which exotoxin is toxic to red blood cells, white blood cells, hepatocytes, platelets, and macrophages, and disrupts smooth muscle in blood vessels?
Alpha toxin
Which exotoxin hydrolyzes membrane phospholipids and causes cell lysis?
Beta toxin
Which exotoxin causes nonspecific membrane toxicity to other mammalian cells and allows proliferation of white blood cells, T cells, and antigen-presenting cells?
Delta toxin
Which type of enterotoxin is associated with staphylococcal-related food poisoning and is resistant to stomach and intestinal enzymes?
Enterotoxin A
Which type of enterotoxin is associated with enterocolitis and could produce pseudomembranes in the stomach?
Enterotoxin B
Which type of enterotoxin is commonly found in milk products and has an emetic effect, causing vomiting?
Enterotoxin C
Which type of enterotoxin is associated with pseudomembranous enterocolitis?
Enterotoxin D
Test your knowledge on Microbial Surface Components Recognizing Adhesive Matrix Molecules (MSCRAMMs) and their role in Staphylococcus. Learn about the binding of Protein A to the cytoplasmic membrane, its affinity for the FC receptor on lgG molecules and complement, and its attachment to white blood cells. Understand the structure of the antibody "Y" and the recognition of antigens by Fab.
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