Podcast
Questions and Answers
Which anion is the second most abundant in the extracellular fluid, next to Chloride?
Which anion is the second most abundant in the extracellular fluid, next to Chloride?
- Phosphate (PO4^3-)
- Lactate (L-)
- Bicarbonate (HCO3-) (correct)
- Sulfate (SO4^2-)
What is the process called when Chloride (Cl-) replaces Bicarbonate (HCO3-) in the RBC?
What is the process called when Chloride (Cl-) replaces Bicarbonate (HCO3-) in the RBC?
- Oxygen Dissociation
- Hemoglobin Exchange
- Chloride Shift (correct)
- Bicarbonate Swap
What happens to O2 when it reaches the lungs?
What happens to O2 when it reaches the lungs?
- It binds with Hemoglobin (HHb) in the RBC
- It dissociates from Hemoglobin (HHb) in the RBC
- It combines with H+ in the RBC
- It is released outside the RBC to be used by the tissues (correct)
When does H+ bind to Hemoglobin (HHb) in the RBC?
When does H+ bind to Hemoglobin (HHb) in the RBC?
In a healthy patient with a normal blood pH (7.35-7.45), what is the main component of total CO2 (tCO2)?
In a healthy patient with a normal blood pH (7.35-7.45), what is the main component of total CO2 (tCO2)?
Flashcards
Second most abundant anion in extracellular fluid?
Second most abundant anion in extracellular fluid?
Bicarbonate (HCO3-)
Cl- replaces HCO3- in RBC?
Cl- replaces HCO3- in RBC?
Chloride Shift
What happens to O2 in the Lungs?
What happens to O2 in the Lungs?
Released from RBCs to be used by the tissues.
When does H+ bind to Hemoglobin (HHb)?
When does H+ bind to Hemoglobin (HHb)?
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Main component of total CO2 (tCO2)?
Main component of total CO2 (tCO2)?
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Study Notes
Extracellular Fluid Composition
- Bicarbonate (HCO3-) is the second most abundant anion in the extracellular fluid, next to Chloride (Cl-).
Chloride Shift
- Chloride (Cl-) replaces Bicarbonate (HCO3-) in the Red Blood Cell (RBC) through a process called the Chloride Shift.
Oxygen Transportation
- When Oxygen (O2) reaches the lungs, it binds to Hemoglobin (Hb) in the Red Blood Cell (RBC).
Hemoglobin and Hydrogen Ions
- Hydrogen ions (H+) bind to Hemoglobin (Hb) in the Red Blood Cell (RBC) when the blood pH drops, forming Hemoglobin-H (HHb).
Total CO2 Composition
- In a healthy patient with a normal blood pH (7.35-7.45), Bicarbonate (HCO3-) is the main component of total CO2 (tCO2).
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