5 Questions
Which anion is the second most abundant in the extracellular fluid, next to Chloride?
Bicarbonate (HCO3-)
What is the process called when Chloride (Cl-) replaces Bicarbonate (HCO3-) in the RBC?
Chloride Shift
What happens to O2 when it reaches the lungs?
It is released outside the RBC to be used by the tissues
When does H+ bind to Hemoglobin (HHb) in the RBC?
When O2 dissociates from Hemoglobin
In a healthy patient with a normal blood pH (7.35-7.45), what is the main component of total CO2 (tCO2)?
H+
Study Notes
Extracellular Fluid Composition
- Bicarbonate (HCO3-) is the second most abundant anion in the extracellular fluid, next to Chloride (Cl-).
Chloride Shift
- Chloride (Cl-) replaces Bicarbonate (HCO3-) in the Red Blood Cell (RBC) through a process called the Chloride Shift.
Oxygen Transportation
- When Oxygen (O2) reaches the lungs, it binds to Hemoglobin (Hb) in the Red Blood Cell (RBC).
Hemoglobin and Hydrogen Ions
- Hydrogen ions (H+) bind to Hemoglobin (Hb) in the Red Blood Cell (RBC) when the blood pH drops, forming Hemoglobin-H (HHb).
Total CO2 Composition
- In a healthy patient with a normal blood pH (7.35-7.45), Bicarbonate (HCO3-) is the main component of total CO2 (tCO2).
Test your knowledge of chloride, bicarbonate, and lactate in clinical chemistry with this quiz. Learn about the chloride shift and the binding of H+ to hemoglobin. Explore the process of releasing O2 in the body.
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