Experimental Design in Memory Reconsolidation
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Experimental Design in Memory Reconsolidation

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Questions and Answers

What was the primary focus of the reminder group on Day 3?

  • To learn List 2 with no prior recall
  • To memorize new objects without any recall
  • To rearrange objects from List 1
  • To recall objects from List 1 after a reminder (correct)
  • What was a key finding regarding the recall performance of the reminder group on Day 5?

  • There were no significant differences compared to the no-reminder group.
  • They showed increased recall due to repetition.
  • Their performance was hindered by List 2 intrusions. (correct)
  • They recalled 20 out of 20 objects perfectly.
  • What is the purpose of using the drug propranolol in reconsolidation-based treatments?

  • To enhance memory recall of traumatic experiences
  • To block reconsolidation of traumatic memories (correct)
  • To induce forgetfulness of the traumatic memory
  • To improve cognitive processing speed in patients
  • Which strategy is effective for exam preparation, according to the depth of processing principle?

    <p>Creating a deep, semantically-rich understanding</p> Signup and view all the answers

    What does retrieval practice emphasize in relation to studying?

    <p>Engaging actively with the material and retrieving information</p> Signup and view all the answers

    During the experiment, what method was used to present List 1 to the subjects?

    <p>By displaying objects in a blue basket</p> Signup and view all the answers

    What can be inferred about the Encoding-specificity principle in exam preparations?

    <p>Exam questions will emphasize meaning-based understanding.</p> Signup and view all the answers

    How did the reminder group's recall performance on Day 5 compare to that of the no-reminder group?

    <p>The reminder group's performance was worse due to interference.</p> Signup and view all the answers

    What is one of the main causes of retrieval failures in long-term memory?

    <p>Poor retrieval cues</p> Signup and view all the answers

    Which of the following describes interference in long-term memory?

    <p>Competing memory trace activations</p> Signup and view all the answers

    What can be a consequence of poor retrieval cues?

    <p>Random intrusions in recall</p> Signup and view all the answers

    Which memory phenomenon involves the retrieval being affected by the context in which information was initially learned?

    <p>State-dependent recall</p> Signup and view all the answers

    What is 'encoding specificity' in the context of memory retrieval?

    <p>Using the same methods to encode and retrieve information</p> Signup and view all the answers

    Which of the following examples illustrates the concept of intrusions in memory recall?

    <p>Remembering a song incorrectly</p> Signup and view all the answers

    What does transfer-appropriate processing suggest about memory retrieval?

    <p>Retrieval is best when the cues match the encoding experience.</p> Signup and view all the answers

    What role do retrieval cues play in accessing long-term memories?

    <p>They assist in activating specific memory traces.</p> Signup and view all the answers

    What was the primary hypothesis tested by Gais et al. in their 2006 study?

    <p>Sleep enhances memory retention following a study session.</p> Signup and view all the answers

    What did the study find about memory consolidation and sleep?

    <p>Memories are consolidated during sleep.</p> Signup and view all the answers

    What is the process called that strengthens memories over time?

    <p>Consolidation</p> Signup and view all the answers

    What type of consolidation occurs over minutes or hours?

    <p>Synaptic consolidation</p> Signup and view all the answers

    What was a potential issue for the awake group in the study?

    <p>They might have experienced greater interference from new experiences.</p> Signup and view all the answers

    Which of the following correctly describes the study design?

    <p>Participants in both groups studied for the same duration with different tests.</p> Signup and view all the answers

    How can interference in memory be reduced?

    <p>Through deep processing</p> Signup and view all the answers

    How was the awake group instructed to minimize interference during their study?

    <p>They were instructed not to read during their downtime.</p> Signup and view all the answers

    What does retrograde amnesia provide evidence for?

    <p>System consolidation</p> Signup and view all the answers

    What kind of retrieval failure often occurs when ineffective retrieval cues are used?

    <p>Tip-of-the-tongue phenomenon</p> Signup and view all the answers

    What usually happens to most memories over time contrary to common intuition?

    <p>They tend to get stronger</p> Signup and view all the answers

    What can cause an intrusion during memory retrieval?

    <p>Retrieving information about an unrelated topic</p> Signup and view all the answers

    What does system consolidation involve?

    <p>Reorganization of long-term memories</p> Signup and view all the answers

    What is a common characteristic of retrograde amnesia in terms of memory loss?

    <p>Most recent memories are lost the most.</p> Signup and view all the answers

    In the example provided, what condition did Patient PZ develop?

    <p>Korsakoff syndrome</p> Signup and view all the answers

    According to the consolidation example, what benefit does a 6-minute delay provide?

    <p>Consolidation of memory materials occurs.</p> Signup and view all the answers

    During which state is memory consolidation suggested to occur most frequently?

    <p>During sleep</p> Signup and view all the answers

    In the consolidation study, how did the delay of 17 seconds impact recall?

    <p>No change in recall was observed.</p> Signup and view all the answers

    What pattern did the percent accuracy of recall demonstrate in the delayed group compared to the immediate group?

    <p>Significantly lower accuracy in the delayed group.</p> Signup and view all the answers

    What did the example involving the terms PUK-DAX and LOC-PED represent?

    <p>Pairs of associated items in recall.</p> Signup and view all the answers

    Which factor did Butters & Cermak identify as influencing the temporal gradient in retrograde amnesia?

    <p>The age at which memories were formed.</p> Signup and view all the answers

    Study Notes

    Experimental Design

    • Participants were divided into two groups: the Reminder group and the No-Reminder group
    • Reminder group: on Day 3, the experimenter reminded participants of the List 1 learning experience, showing them objects in the blue basket
    • No-Reminder group: no reminder occurred on Day 3
    • Findings: on Day 5, the Reminder group showed worse recall of List 1 and more intrusions from List 2, meaning the reminder made List 1 memories less stable, more vulnerable to interference
    • Interpretation: This experiment supports the theory of reconsolidation: reminding a learned memory makes it vulnerable to change

    Clinical Applications of Reconsolidation

    • Reconsolidation-based treatments have shown potential for treating PTSD
    • Procedure: Reminding a patient of a traumatic experience and administering propranolol (a drug affecting memory consolidation) during the reminder period, aiming to block the reconsolidation process.
    • Outcome: When reminded of the traumatic experience a week later, patients reported significantly lower levels of fear

    Studying for Exams

    • Depth of processing: aiming for a deep, meaningful understanding of the material for better retention
    • Retrieval practice: instead of just reading repeatedly, actively retrieving information to test oneself and strengthen memories.
    • Encoding Specificity Principle: understanding that the questions on an exam will be meaning-based, based on the way information was encoded during learning

    Forgetting and Retrieval

    • Retrieval failures: happen due to poor retrieval cues and interference
    • Poor retrieval cues: the cues used during retrieval are not specific enough to bring back the target memory
    • Interference: refers to competing memories activated by the retrieval cues, hindering access to the target memory
    • Intrusions: the result of interference, where incorrect information is retrieved instead of the correct one

    Example of Interference

    • Study: participants learn lists of U.S. presidents and their details
    • Findings: retrieving similar information about different presidents can cause interference, leading to intrusions, such as mistakenly retrieving information about Adams when asked about Madison
    • Conclusion: interference can lead to incorrect retrieval or even the inability to retrieve any information at all.

    Interference and Distinctiveness

    • Reducing interference: creating distinct memories by using deep processing techniques
    • Deep processing: making learned items unique through deeper understanding and meaningful connections
    • Summary of Retrieval Failure: forgetting often originates from retrieval failure, either due to ineffective cues or competing memories during retrieval.

    Consolidation

    • General principle: new memories are initially weak and tend to get stronger with time
    • Consolidation: the brain processes that strengthen memories over time
    • Synaptic Consolidation: takes place over minutes to hours and involves changes to synapses
    • System Consolidation: takes place over months to years and involves the reorganization of memories in the brain

    System Consolidation and Retrograde Amnesia (RA)

    • Evidence: retrograde amnesia provides evidence for system consolidation. Patients with RA experience memory loss most severe for recent memories and least severe for distant memories
    • Temporal Gradient: memory loss is greatest for recent memories and gradually decreases for older memories
    • Explanation: because system consolidation takes a long time, recent memories are more susceptible to disruption than older memories

    Consolidation and Sleep

    • Sleep: plays a crucial role in memory consolidation
    • Gais et al., 2006 Participants studied vocabulary words and were divided into two groups: Sleep group and Awake group.
    • Results: the Sleep group showed significantly better recall of the learned vocabulary compared to the Awake group, indicating sleep enhances memory consolidation.
    • Interpretation: sleep seems to facilitate memory consolidation, potentially enhancing retention of new information studied immediately before sleep.

    Caveat:

    • While sleep appears to support memory consolidation, the Awake group in the study might have experienced more interference from new experiences during their waking period, which could have negatively impacted their memory performance.

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    Description

    This quiz explores the experimental design involving reminders and their effects on memory stability and recall. It discusses two participant groups and highlights the implications for understanding reconsolidation and potential clinical applications, especially in PTSD treatment.

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