Excitation-Contraction Coupling in Smooth Muscle

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Which enzyme is responsible for the dephosphorylation of myosin light chains?

Myosin light chain phosphatase

What happens to the affinity of the myosin head for ATP when myosin light chains are dephosphorylated?

It decreases

What is the latch state?

The state where myosin is attached to actin

Which of the following is a major difference between smooth muscle and skeletal/cardiac muscle in terms of cross-bridge cycle regulation?

Smooth muscle regulates the interaction between actin and myosin by altering the properties of myosin itself through phosphorylation of myosin light chains.

Which enzyme phosphorylates myosin light chains in smooth muscle?

Myosin light chain kinase (MLCK)

What activates myosin light chain kinase (MLCK) in smooth muscle?

Intracellular concentration of calcium ions

Test your knowledge on excitation-contraction coupling in smooth muscle. Learn about the interactions of actin and myosin, the role of calcium, and the ATP hydrolysis process. Discover the similarities and differences between smooth, skeletal, and cardiac muscle.

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