Post-transcriptional regulation of eukaryotic genes expression
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Questions and Answers

What is the complex formed from the association of each snRNA with core splicing proteins?

  • snRNP (correct)
  • snRNA
  • Core complex
  • Spliceosome

How many steps are involved in the assembly of the spliceosome?

  • 6 (correct)
  • 4
  • 5
  • 7

What is the function of SR proteins in splicing regulation?

  • To activate splicing (correct)
  • To inhibit intron definition
  • To cleave the 5' splice site
  • To form a bridge between U1 and U2AF

What is the mechanism by which U1 and SR proteins define the 5' splice region?

<p>By forming a bridge with U2AF (C)</p> Signup and view all the answers

What is the result of alternative splicing?

<p>Increased protein diversity (C)</p> Signup and view all the answers

What is the function of adenosine deaminase in RNA editing?

<p>To convert adenosine to inosine (C)</p> Signup and view all the answers

What is the result of RNA localization?

<p>Pattern formation and fate specification (B)</p> Signup and view all the answers

What is the mechanism of trans-splicing?

<p>Exons from different mRNA molecules are joined together (A)</p> Signup and view all the answers

What is the function of APOBEC1 in RNA editing?

<p>To convert cytidine to uridine (A)</p> Signup and view all the answers

What is the direction of external degradation of mRNA?

<p>Both 3' to 5' and 5' to 3' (A)</p> Signup and view all the answers

Which of the following best describes the interaction between U1 and SR proteins in splicing regulation?

<p>U1 defines the 3' splice site, while SR proteins define the 5' splice region (C)</p> Signup and view all the answers

What is the primary function of the spliceosome in eukaryotic gene expression?

<p>To regulate the joining of exons to form mature mRNA (B)</p> Signup and view all the answers

What is the outcome of the conversion of adenosine to inosine by adenosine deaminase during RNA editing?

<p>The modification of the mRNA sequence (A)</p> Signup and view all the answers

What is the primary function of hnRNPs in splicing regulation?

<p>To inhibit intron definition interactions (D)</p> Signup and view all the answers

What is the outcome of the assembly of high-order repressive complexes in splicing regulation?

<p>The inhibition of exon definition interactions (C)</p> Signup and view all the answers

What is the primary function of U2AF in splicing regulation?

<p>To bind to the 3' splice site (B)</p> Signup and view all the answers

What is the outcome of alternative splicing in eukaryotic gene expression?

<p>The creation of protein diversity (B)</p> Signup and view all the answers

What is the primary function of compartmentalization in RNA localization?

<p>To specialize regions within a cell (B)</p> Signup and view all the answers

What is the outcome of internal cleavage by endonucleases in RNA degradation?

<p>The cleavage of mRNA at specific sites (A)</p> Signup and view all the answers

What is the primary function of APOBEC1 in RNA editing?

<p>To convert cytidine to uridine (C)</p> Signup and view all the answers

What is the consequence of U1 + SR protein defining the 5' splice region?

<p>Activation of splicing (C)</p> Signup and view all the answers

What is the role of U2AF in the splicing process?

<p>Recognition of the 3' splice site (A)</p> Signup and view all the answers

What is the outcome of the conversion of cytidine to uridine by APOBEC1?

<p>RNA editing (D)</p> Signup and view all the answers

What is the mechanism by which U2AF and U1/SR protein interact?

<p>Formation of a bridge between the 5' and 3' splice sites (B)</p> Signup and view all the answers

What is the result of RNA degradation by exonucleases?

<p>Complete degradation of the mRNA (B)</p> Signup and view all the answers

What is the role of compartmentalization in RNA localization?

<p>Localisation of mRNA to specific regions (B)</p> Signup and view all the answers

What is the outcome of the assembly of the spliceosome?

<p>Formation of a lariat (B)</p> Signup and view all the answers

What is the role of hnRNPs in splicing regulation?

<p>Inhibiting intron definition interactions (A)</p> Signup and view all the answers

What is the consequence of trans-splicing?

<p>Joining of exons from different mRNA molecules (C)</p> Signup and view all the answers

What is the mechanism of internal cleavage by endonuclease?

<p>Cleavage of the mRNA at a specific site (D)</p> Signup and view all the answers

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