Eukaryote Chromosomes and Karyotypes

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Questions and Answers

Eukaryotic chromosomes come in pairs, also known as homologues.

True (A)

How many chromosomes do normal humans have?

46

Each chromosome in a pair comes from the same parent.

False (B)

Autosomes are found in both males and females.

<p>True (A)</p> Signup and view all the answers

How many pairs of autosomes are present in humans?

<p>22</p> Signup and view all the answers

Autosomes in a pair are not homologous.

<p>False (B)</p> Signup and view all the answers

Sex chromosomes determine an individual's gender.

<p>True (A)</p> Signup and view all the answers

The X and Y chromosomes are homologous.

<p>False (B)</p> Signup and view all the answers

The X chromosome is smaller than the Y chromosome.

<p>False (B)</p> Signup and view all the answers

The Y chromosome carries a large number of genes.

<p>False (B)</p> Signup and view all the answers

In humans and mammals, females have XX chromosomes and males have XY chromosomes.

<p>True (A)</p> Signup and view all the answers

What is a karyotype?

<p>A classification of chromosomes based on their size, position of the centromere, and banding pattern.</p> Signup and view all the answers

A karyotype is a complete set of chromosomes from a cell, including their size, number, and shape.

<p>True (A)</p> Signup and view all the answers

The goal of cell division is to equally partition two or more identical copies of genetic material between two daughter cells.

<p>True (A)</p> Signup and view all the answers

Prokaryotes are comparatively simple, having only one chromosome, which makes dividing chromosomes relatively easy.

<p>True (A)</p> Signup and view all the answers

Eukaryotes, with their longer DNA and multiple chromosomes, find it easier to sort chromosomes during division than prokaryotes do.

<p>False (B)</p> Signup and view all the answers

Mitosis is a complex process that ensures each daughter cell ends up with the same number and type of chromosomes as the parent cell.

<p>True (A)</p> Signup and view all the answers

Prokaryotic cell division is required for both development and reproduction.

<p>True (A)</p> Signup and view all the answers

In eukaryotic cells, chromosomes are found in the cytoplasm, not the nucleus.

<p>False (B)</p> Signup and view all the answers

Chromosomes are tightly packaged DNA and are only found during cell division.

<p>True (A)</p> Signup and view all the answers

Chromatin is unwound DNA and is found throughout interphase.

<p>True (A)</p> Signup and view all the answers

DNA is not used for macromolecule synthesis during chromosome formation.

<p>True (A)</p> Signup and view all the answers

DNA is being used for macromolecule synthesis during interphase, when DNA exists as chromatin.

<p>True (A)</p> Signup and view all the answers

Chromosomes are formed through replication and not by the joining of existing chromatids.

<p>True (A)</p> Signup and view all the answers

Sister chromatids are identical copies of DNA.

<p>True (A)</p> Signup and view all the answers

Chromosomes are mainly composed of protein.

<p>False (B)</p> Signup and view all the answers

A gene is a discrete heritable unit that carries traits.

<p>True (A)</p> Signup and view all the answers

Alleles are different versions of a gene.

<p>True (A)</p> Signup and view all the answers

Alleles can only differ by one or a few nucleotides.

<p>True (A)</p> Signup and view all the answers

Different alleles always code for different phenotypes.

<p>False (B)</p> Signup and view all the answers

A chromatid is considered a chromatid as long as it is associated with a sister chromatid at the centromere.

<p>True (A)</p> Signup and view all the answers

When sister chromatids separate after metaphase, they become two different chromosomes.

<p>True (A)</p> Signup and view all the answers

The eukaryotic cell cycle includes interphase and mitosis.

<p>True (A)</p> Signup and view all the answers

Interphase consists of three stages: G1, S, and G2.

<p>True (A)</p> Signup and view all the answers

The mitotic phase includes mitosis and cytokineses.

<p>True (A)</p> Signup and view all the answers

Interphase is longer and more complex than mitosis.

<p>True (A)</p> Signup and view all the answers

Interphase is responsible for DNA replication, while mitosis is responsible for cell growth.

<p>False (B)</p> Signup and view all the answers

During prophase, the nucleoli disappear, the mitotic spindle forms, and the centrosomes separate.

<p>True (A)</p> Signup and view all the answers

Metaphase involves the alignment of chromosomes at the metaphase plate, with kinetochores attached to microtubules.

<p>True (A)</p> Signup and view all the answers

Anaphase is the shortest stage of mitosis, where sister chromatids are pulled apart, becoming individual chromosomes.

<p>True (A)</p> Signup and view all the answers

Telophase is when the nuclear envelope reforms, chromosomes decondense, and cytokinesis begins.

<p>True (A)</p> Signup and view all the answers

Cytokinesis is the division of the cytoplasm, resulting in two daughter cells.

<p>True (A)</p> Signup and view all the answers

Meiosis I is the first division of meiosis, in which homologous chromosomes are separated from each other.

<p>True (A)</p> Signup and view all the answers

Meiosis II separates sister chromatids, resulting in four haploid daughter cells.

<p>True (A)</p> Signup and view all the answers

Crossing over is a process that happens during prophase I of meiosis, making sister chromatids no longer identical.

<p>True (A)</p> Signup and view all the answers

During independent assortment, each human can potentially produce over 8.3 million different gametes in meiosis I.

<p>True (A)</p> Signup and view all the answers

A couple can potentially produce over 64 trillion different zygotes during fertilization.

<p>True (A)</p> Signup and view all the answers

Crossing over is a key factor in creating genetic diversity.

<p>True (A)</p> Signup and view all the answers

Synapsis is the pairing of homologous chromosomes during prophase I of meiosis.

<p>True (A)</p> Signup and view all the answers

A chiasma is the site where crossing over occurs.

<p>True (A)</p> Signup and view all the answers

Recombinant chromosomes are chromosomes that have undergone crossing over, resulting in the exchange of genetic material.

<p>True (A)</p> Signup and view all the answers

Flashcards

Chromosomes

Paired structures found in the nucleus of eukaryotic cells that carry genetic information in the form of DNA.

Homologous Chromosomes

A pair of chromosomes that have the same genes in the same order, one inherited from each parent.

Sex Chromosomes

Chromosomes that determine an individual's sex. In humans, they are X and Y.

Autosomes

Chromosomes that are not involved in determining sex. In humans, there are 22 pairs of autosomes.

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Karyotype

The complete set of chromosomes in a cell, organized by size and shape.

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Cell Division

The process by which cells replicate themselves, resulting in two daughter cells with identical genetic material to the parent cell.

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Chromatin

The loosely packed form of DNA found in the nucleus of a cell during interphase. It is accessible for gene expression.

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Chromosome

The tightly packed form of DNA found during cell division. It is not actively being used for gene expression.

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Alleles

Alternative forms of a gene that occupy the same locus on homologous chromosomes.

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Locus

The specific location of a gene on a chromosome.

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Interphase

The stage of the cell cycle where the cell grows and carries out its normal functions.

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Mitosis

The process of cell division that results in two daughter cells with the same number of chromosomes as the parent cell.

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Mitotic Spindle

The set of microtubules that organize and move chromosomes during mitosis and meiosis.

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Cytokinesis

The process by which the cytoplasm of the cell divides, creating two daughter cells.

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Prophase

The first stage of mitosis, where the chromosomes condense and become visible.

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Metaphase

The stage of mitosis where the chromosomes line up at the center of the cell.

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Anaphase

The stage of mitosis where the sister chromatids separate and move to opposite poles of the cell.

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Telophase

The final stage of mitosis, where the nuclear envelope reforms around each set of chromosomes, and the cell divides.

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Meiosis

The process of cell division that results in four daughter cells, each with half the number of chromosomes as the parent cell.

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Meiosis I

The first division of meiosis, where homologous chromosomes pair up and separate into two daughter cells.

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Meiosis II

The second division of meiosis, where sister chromatids separate into four daughter cells.

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Crossing Over

The exchange of genetic material between homologous chromosomes during prophase I of meiosis, creating genetic diversity.

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Independent Assortment

The random alignment of homologous chromosomes at the metaphase plate during Meiosis I, resulting in genetically diverse gametes.

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Fertilization

The fusion of male and female gametes (sperm and egg) to form a zygote, initiating the development of a new organism.

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DNA Replication

The process of DNA replication.

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DNA

A single, continuous molecule of DNA consisting of two strands joined together by hydrogen bonds.

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Transcription

The process of copying the genetic code from DNA into RNA.

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Translation

The process of using RNA to make proteins.

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Study Notes

Eukaryote Chromosomes

  • Eukaryotic chromosomes come in pairs (homologous).
  • Humans have 46 chromosomes in 23 pairs.
  • Each pair has one chromosome from the mother and one from the father.
  • Autosomes are found in both males and females.
  • Humans have 22 pairs of autosomes.
  • Autosomes of the same size and structure are called homologues.
  • The remaining pair, sex chromosomes (X and Y), determine gender.
  • The X chromosome is larger than the Y chromosome and carries more genes.
  • The Y chromosome has fewer genes.
  • Females are XX and males are XY in humans and other mammals.

Karyotype

  • A karyotype is a picture of chromosomes arranged by size and shape.
  • Chromosomes are categorized by their centromere position.
  • Size, shape, and number of chromosomes are considered in a karyotype.
  • Karyotyping often uses white blood cells during metaphase.

Human Sexual Cycle

  • The female reproductive system contains ovaries.
  • The female life cycle contains only about 400 viable oocytes.
  • Males have testes.
  • Meiosis results in haploid gametes (sperm and ova).
  • Fertilization of the ovum by a sperm results in a zygote.
  • The zygote develops through mitotic growth.
  • Diploid adults result.

Chromosome Sorting

  • Cell division aims to distribute identical genetic material between daughter cells.
  • Prokaryotes are simpler, with one chromosome and quick chromosome sorting.
  • Eukaryotes, with multiple chromosomes, face a more complex process.
  • Mitosis ensures that each daughter cell inherits the identical number and type of chromosomes of the parent cell.

Chromosomes vs. Chromatin

  • Chromosomes are tightly packaged DNA found during cell division.
  • Chromatin is unwound DNA located throughout interphase for macromolecule synthesis.

Mitosis

  • Mitosis is the process of cell division for growth, development, and tissue renewal.
  • The stages of mitosis are interphase, prophase, metaphase, anaphase, telophase, and cytokinesis.
  • G2 of interphase: DNA continues to replicate in preparation for mitosis.
  • Prophase: Chromosomes condense, nuclear envelope breaks down, mitotic spindle forms, centrosomes separate.
  • Metaphase: Chromosomes align at the metaphase plate.
  • Anaphase: Sister chromatids separate and move to opposite poles.
  • Telophase: Chromosomes decondense, nuclear envelopes reform, and the mitotic spindle breaks down.
  • Cytokinesis: The cytoplasm divides to create two daughter cells.

Meiosis I

  • Meiosis I is the first stage of meiosis.
  • It reduces chromosome number to half in a process called reduction in ploidy.
  • Homologous chromosomes pair to form tetrads, exchange genetic material (crossing over), then separate.

Meiosis II

  • Meiosis II is the second stage of meiosis.
  • Sister chromatids separate to produce four haploid daughter cells.  This is identical to mitosis but with haploid cells. No DNA replication occurs between meiosis I and meiosis II

Variation via the Sexual Cycle

  • Crossing over produces new genetic combinations in gametes.
  • Independent assortment mixes chromosomes in gametes from one individual.
  • Random fertilization of unique haploid eggs and sperm creates unique diploid zygotes, increasing genetic variation.

Cytokinesis

  • Cytokinesis is the division of the cytoplasm to form two separate daughter cells.
  • Animals: Cleavage furrow forms and pinches the cell in two.
  • Plants: Cell plate forms in the middle of the dividing cell.

Alleles and Loci

  • Genes code for traits, and different alleles of a gene result in variations in an observable trait.

  • Alleles are variants of a gene.

  • Loci are the specific positions of a gene on a chromosome.

  • Different alleles may or may not produce different observable traits.

Prophase in detail

  • Chromatic condensation
  • Nucleoli disappear
  • Mitotic spindle forms
  • Centrosome separation

Telophase in detail

  • "Sisters" at opposite poles
  • Nuclear envelope reformation
  • Chromosome decondensation
  • Cytokinesis already under way

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