Podcast
Questions and Answers
Which drug is associated with a significant decrease in intraocular pressure?
Which drug is associated with a significant decrease in intraocular pressure?
- Propofol (correct)
- Opioids
- Thiopental
- Lidocaine
What is the most commonly reported adverse event related to propofol?
What is the most commonly reported adverse event related to propofol?
- Bradycardia
- Respiratory depression
- Pain on injection (correct)
- Allergic reactions
Which drug has been described to cause profound bradycardia and asystole even with anticholinergic prophylaxis?
Which drug has been described to cause profound bradycardia and asystole even with anticholinergic prophylaxis?
- Lidocaine
- Opioids
- Thiopental
- Propofol (correct)
Which drug does not alter hepatic or renal function?
Which drug does not alter hepatic or renal function?
Which drug has been associated with hepatocellular injury, lactic acidosis, bradydysrhythmias, and rhabdomyolysis?
Which drug has been associated with hepatocellular injury, lactic acidosis, bradydysrhythmias, and rhabdomyolysis?
Propofol is primarily cleared from the plasma through which process?
Propofol is primarily cleared from the plasma through which process?
What is the recommended induction dose of propofol for children?
What is the recommended induction dose of propofol for children?
What is the typical conscious sedation dose range of propofol?
What is the typical conscious sedation dose range of propofol?
What is one of the therapeutic applications of propofol at subhypnotic doses?
What is one of the therapeutic applications of propofol at subhypnotic doses?
What effect does propofol have on cerebral blood flow?
What effect does propofol have on cerebral blood flow?
Which of the following best describes a sedative?
Which of the following best describes a sedative?
What is the chemical structure of propofol?
What is the chemical structure of propofol?
What is the recommended formulation of propofol for IV administration?
What is the recommended formulation of propofol for IV administration?
Which of the following is a risk associated with mixing propofol with lidocaine?
Which of the following is a risk associated with mixing propofol with lidocaine?
What is the mechanism of action of propofol?
What is the mechanism of action of propofol?
Which of the following reflects the differences in onset and duration among benzodiazepines?
Which of the following reflects the differences in onset and duration among benzodiazepines?
Which of the following is a side effect of chronic administration of benzodiazepines?
Which of the following is a side effect of chronic administration of benzodiazepines?
Which of the following substances exert synergistic sedative effects with benzodiazepines?
Which of the following substances exert synergistic sedative effects with benzodiazepines?
Which of the following is a sign of benzodiazepine dependence?
Which of the following is a sign of benzodiazepine dependence?
Which of the following benzodiazepines is water-soluble with a rapid metabolism?
Which of the following benzodiazepines is water-soluble with a rapid metabolism?
Which of the following is a characteristic of etomidate?
Which of the following is a characteristic of etomidate?
What is the principal limiting aspect of etomidate?
What is the principal limiting aspect of etomidate?
Which of the following is a side effect of etomidate on the cardiovascular system?
Which of the following is a side effect of etomidate on the cardiovascular system?
What is the mechanism of action of benzodiazepines?
What is the mechanism of action of benzodiazepines?
Which benzodiazepine is most commonly used?
Which benzodiazepine is most commonly used?
Which of the following is true about the administration of Diazepam for sedation during regional and brief therapeutic procedures?
Which of the following is true about the administration of Diazepam for sedation during regional and brief therapeutic procedures?
What is the protein binding characteristic of Diazepam?
What is the protein binding characteristic of Diazepam?
How is Diazepam metabolized in the body?
How is Diazepam metabolized in the body?
Which of the following is true about the elimination half-time of Diazepam?
Which of the following is true about the elimination half-time of Diazepam?
What is the commercial preparation of Diazepam?
What is the commercial preparation of Diazepam?
Which drug is associated with a high incidence of pain on injection?
Which drug is associated with a high incidence of pain on injection?
Which drug is known to decrease intraocular pressure?
Which drug is known to decrease intraocular pressure?
Which drug is NOT known to alter hepatic or renal function?
Which drug is NOT known to alter hepatic or renal function?
Which drug has been associated with hepatocellular injury, lactic acidosis, bradydysrhythmias, and rhabdomyolysis?
Which drug has been associated with hepatocellular injury, lactic acidosis, bradydysrhythmias, and rhabdomyolysis?
Which drug is a selective modulator of GABAA receptors?
Which drug is a selective modulator of GABAA receptors?
Which of the following is a clinical use of propofol?
Which of the following is a clinical use of propofol?
What is the recommended induction dose of propofol for children?
What is the recommended induction dose of propofol for children?
What is the typical conscious sedation dose range of propofol?
What is the typical conscious sedation dose range of propofol?
Which of the following is a therapeutic application of propofol at subhypnotic doses?
Which of the following is a therapeutic application of propofol at subhypnotic doses?
What effect does propofol have on cerebral blood flow?
What effect does propofol have on cerebral blood flow?
Which of the following is a characteristic of propofol?
Which of the following is a characteristic of propofol?
What is the recommended formulation of propofol for IV administration?
What is the recommended formulation of propofol for IV administration?
What is the mechanism of action of propofol?
What is the mechanism of action of propofol?
Which of the following is a risk associated with mixing propofol with lidocaine?
Which of the following is a risk associated with mixing propofol with lidocaine?
What is the most commonly reported adverse event related to propofol?
What is the most commonly reported adverse event related to propofol?
Which of the following is a characteristic of etomidate?
Which of the following is a characteristic of etomidate?
What is the principal limiting aspect of etomidate?
What is the principal limiting aspect of etomidate?
Which of the following is a side effect of etomidate on the cardiovascular system?
Which of the following is a side effect of etomidate on the cardiovascular system?
What is the recommended formulation of propofol for IV administration?
What is the recommended formulation of propofol for IV administration?
What is the most commonly reported adverse event related to propofol?
What is the most commonly reported adverse event related to propofol?
Which of the following is true about the protein binding characteristic of Diazepam?
Which of the following is true about the protein binding characteristic of Diazepam?
What is the elimination half-time of Diazepam in healthy volunteers?
What is the elimination half-time of Diazepam in healthy volunteers?
What is the recommended time to administer Diazepam before surgery?
What is the recommended time to administer Diazepam before surgery?
What is the primary route of metabolism for Diazepam?
What is the primary route of metabolism for Diazepam?
What is the commercial preparation of Diazepam?
What is the commercial preparation of Diazepam?
Which of the following factors contribute to the differences in onset and duration among benzodiazepines?
Which of the following factors contribute to the differences in onset and duration among benzodiazepines?
Which of the following substances exert synergistic sedative effects with benzodiazepines?
Which of the following substances exert synergistic sedative effects with benzodiazepines?
Which of the following is a side effect of chronic administration of benzodiazepines?
Which of the following is a side effect of chronic administration of benzodiazepines?
Which of the following substances can slow down the metabolism of midazolam?
Which of the following substances can slow down the metabolism of midazolam?
Which of the following statements is true about the effects of midazolam on the cardiovascular system?
Which of the following statements is true about the effects of midazolam on the cardiovascular system?
Propofol is a sedative-hypnotic drug
Propofol is a sedative-hypnotic drug
Anxiolytics are drugs that reduce anxiety
Anxiolytics are drugs that reduce anxiety
Propofol is primarily cleared from the plasma through renal excretion
Propofol is primarily cleared from the plasma through renal excretion
Propofol is primarily metabolized by hepatic oxidative metabolism
Propofol is primarily metabolized by hepatic oxidative metabolism
Propofol has a short context-sensitive half-time and short site equilibrium
Propofol has a short context-sensitive half-time and short site equilibrium
Propofol can modulate the postoperative hemodynamic response in cardiac surgery
Propofol can modulate the postoperative hemodynamic response in cardiac surgery
Propofol decreases cerebral blood flow and intracranial pressure
Propofol decreases cerebral blood flow and intracranial pressure
Propofol is associated with a significant decrease in intraocular pressure.
Propofol is associated with a significant decrease in intraocular pressure.
Propofol does not alter hepatic or renal function.
Propofol does not alter hepatic or renal function.
Propofol has been described to cause profound bradycardia and asystole even with anticholinergic prophylaxis.
Propofol has been described to cause profound bradycardia and asystole even with anticholinergic prophylaxis.
Propofol is a selective modulator of GABAA receptors.
Propofol is a selective modulator of GABAA receptors.
Etomidate is primarily metabolized by hepatic microsomal enzymes and plasma esterases.
Etomidate is primarily metabolized by hepatic microsomal enzymes and plasma esterases.
Etomidate is highly protein bound to albumin.
Etomidate is highly protein bound to albumin.
Etomidate has a longer terminal elimination half-life compared to propofol.
Etomidate has a longer terminal elimination half-life compared to propofol.
Etomidate can be used as an alternative to propofol or barbiturates for IV induction.
Etomidate can be used as an alternative to propofol or barbiturates for IV induction.
True or false: Diazepam is commonly used as part of the anesthesia care plan.
True or false: Diazepam is commonly used as part of the anesthesia care plan.
True or false: Diazepam is rapidly absorbed from the GI tract with near 100% bioavailability.
True or false: Diazepam is rapidly absorbed from the GI tract with near 100% bioavailability.
True or false: Diazepam has a longer elimination half-time than lorazepam.
True or false: Diazepam has a longer elimination half-time than lorazepam.
True or false: Benzodiazepines have a built-in ceiling effect that prevents them from exceeding the physiologic maximum of GABA inhibition.
True or false: Benzodiazepines have a built-in ceiling effect that prevents them from exceeding the physiologic maximum of GABA inhibition.
True or false: Differences in onset and duration among benzodiazepines reflect differences in potency, lipid solubility, and pharmacokinetics.
True or false: Differences in onset and duration among benzodiazepines reflect differences in potency, lipid solubility, and pharmacokinetics.
True or false: Benzodiazepines decrease adenosine degradation by inhibiting the nucleoside transporter, resulting in reduced cardiac oxygen demand and coronary vasodilation.
True or false: Benzodiazepines decrease adenosine degradation by inhibiting the nucleoside transporter, resulting in reduced cardiac oxygen demand and coronary vasodilation.
True or false: Benzodiazepines exert synergistic sedative effects with alcohol, inhaled anesthetics, opioids, and alpha2 agonists.
True or false: Benzodiazepines exert synergistic sedative effects with alcohol, inhaled anesthetics, opioids, and alpha2 agonists.
