Ethical Principles in Laboratory Animal Use Quiz
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Questions and Answers

Which of the following is NOT one of the ethical principles discussed in the text?

  • Non-Maleficence
  • Individual Autonomy (correct)
  • Respect for Life
  • Societal Benefit

    • What are the Three Rs in the context of ethical considerations?

  • Replacement, Reduction, Refinement (correct)
  • Rigorousness, Reliability, Reproducibility
  • Reduction, Rejection, Relocation
  • Reassessment, Reevaluation, Reiteration

    • Which organization is responsible for the Good Laboratory Practices in the United States?

  • Environmental Protection Agency
  • Food and Drug Administration (correct)
  • Institute for Laboratory Animal Research
  • Public Health Service

    • What is the primary focus of the Public Health Service Policy on Humane Care and Use of Animals?

    <p>Ensuring animal welfare in research</p> Signup and view all the answers

    Which entity publishes the 'Guide for the Care and Use of Laboratory Animals'?

    <p>Institute for Laboratory Animal Research</p> Signup and view all the answers

    What is the focus of the Institute for Laboratory Animal Research?

    <p>Providing guidance for the care and use of laboratory animals</p> Signup and view all the answers

    What is the significance of the 'Guide for the Care and Use of Laboratory Animals'?

    <p>It provides ethical guidelines for laboratory animal use</p> Signup and view all the answers

    What is the focus of utilitarianism in ethics?

    <p>Maximizing good consequences and minimizing bad ones</p> Signup and view all the answers

    Which principle is emphasized in deontological theories?

    <p>Emphasizing moral imperatives independent of consequences</p> Signup and view all the answers

    What do the 'Five Freedoms' address?

    <p>Freedom from malnutrition, discomfort, injury, fear, and ability to express normal behavior</p> Signup and view all the answers

    What did NASA develop in 1996 for the ethical use of animals in research?

    <p>The Sundowner Principles</p> Signup and view all the answers

    What does the respect for life principle in laboratory animal ethics require?

    <p>Animals used in research to be of appropriate species and health status</p> Signup and view all the answers

    What is the focus of value-based ethics?

    <p>Promoting personal virtues and character traits</p> Signup and view all the answers

    What is the primary aim of the Sundowner Principles developed by NASA?

    <p>Emphasizing stewardship, respect for life, societal benefit, and non-maleficence</p> Signup and view all the answers

    What is the societal benefit principle in laboratory animal ethics used to justify?

    <p>Biomedical and behavioral research for the advancement of biological knowledge and the protection of health</p> Signup and view all the answers

    What does normative veterinary ethics seek?

    <p>Correct principles of good and bad, right and wrong, and correct norms for veterinary professional behavior</p> Signup and view all the answers

    What is a core concern of veterinary ethics?

    <p>Animal welfare</p> Signup and view all the answers

    What does normative laboratory animal use ethics examine?

    <p>General ethical concepts within the context of descriptive laboratory animal use ethics</p> Signup and view all the answers

    What does moral theory involve in relation to animals?

    <p>The moral value of animals relative to humans, moral status or standing, and the concept of sentience</p> Signup and view all the answers

    What is the aim of the chapter on ethical considerations in animal research?

    <p>To provide information useful for individuals involved in animal-based research, testing, and teaching</p> Signup and view all the answers

    Who are the competing interests in animal research according to the text?

    <p>Scientists, technicians, veterinary colleagues, the public, and concern for the animals</p> Signup and view all the answers

    What does the search for an appropriate ethical solution rarely lead to?

    <p>A complete and absolute answer</p> Signup and view all the answers

    What does the concept of moral agents involve according to the text?

    <p>Humans have obligations and responsibility toward other beings, which leads to the belief that it is right to minimize the pain and distress felt by other sentient beings</p> Signup and view all the answers

    What does potential ethical challenges confronting laboratory animal professionals using rodents and rabbits involve?

    <p>Discussed ethical challenges confronting laboratory animal professionals using rodents and rabbits</p> Signup and view all the answers

    What is referenced in the text for use by individuals involved in animal research?

    <p>Relevant values and standards found in various principles and guidelines</p> Signup and view all the answers

    What does moral theory involve in relation to animals?

    <p>The moral value of animals relative to humans, moral status or standing, and the concept of sentience</p> Signup and view all the answers

    When did the historical development of ethical principles for animal experimentation date back to?

    <p>19th century in the UK and the US</p> Signup and view all the answers

    What are the key principles outlined in the U.S. Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training (1985)?

    <p>Animal welfare, relevance of procedures to human or animal health, selection of appropriate species and quality, and the use of minimal animals required for valid results</p> Signup and view all the answers

    What should be done for procedures causing more than momentary or slight pain or distress?

    <p>Performed with appropriate sedation, analgesia, or anesthesia</p> Signup and view all the answers

    Who should be appropriately qualified and experienced for conducting procedures on living animals?

    <p>Investigators and other personnel</p> Signup and view all the answers

    What do the professional guidelines for laboratory animal use emphasize?

    <p>The humane care and use of research animals</p> Signup and view all the answers

    Study Notes

    Ethical Principles and Guidelines for Laboratory Animal Use

    • Sundowner Principles address the use of sedation, analgesia, anesthesia, humane endpoints, veterinary care, and personnel qualifications.
    • Descriptive ethics studies actual values or standards of a profession, with the Sundowner, CIOMS, and IRAC principles being major components in governing laboratory animal use.
    • Historical development of ethical principles for animal experimentation dates back to the 19th century in the UK and the US.
    • The Interagency Research Animal Committee (IRAC) U.S. Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training (1985) outline key principles for animal use in research, testing, and training.
    • The principles emphasize the importance of animal welfare, relevance of procedures to human or animal health, selection of appropriate species and quality, and the use of minimal animals required for valid results.
    • Proper use of animals includes the avoidance or minimization of discomfort, distress, and pain, with the consideration that procedures causing pain or distress in humans may also do so in animals.
    • Procedures causing more than momentary or slight pain or distress should be performed with appropriate sedation, analgesia, or anesthesia, and animals suffering severe or chronic pain should be painlessly killed.
    • Living conditions of animals should be appropriate for their species, and veterinary care should be provided as indicated.
    • Investigators and other personnel should be appropriately qualified and experienced for conducting procedures on living animals, and in-service training for humane care and use of laboratory animals should be provided.
    • Exceptions to the principles should be made with appropriate review, and solely for teaching or demonstration purposes.
    • Professional guidelines for laboratory animal use include the Principles of Veterinary Medical Ethics, Veterinary Oath of the American Veterinary Medical Association, and Position Statements of the American Association for Laboratory Animal Science (AALAS), all emphasizing the humane care and use of research animals.
    • The commitment to the humane care and use of research animals is central to these codes of conduct, principles, statements of ethics, and position statements.

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    Ethical Considerations and Regulatory Issues PDF

    Description

    Test your knowledge of ethical principles and guidelines for laboratory animal use with this quiz. Explore the historical development of ethical standards, major components governing laboratory animal use, and key principles outlined for animal research, testing, and training. Gain insights into the importance of animal welfare, appropriate living conditions, and the qualifications of personnel while ensuring humane care and use of research animals.

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