Escherichia coli (Lec 20)

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Questions and Answers

Which type of bacteria is Escherichia coli?

  • Branched bacteria
  • Gram-positive spherical bacteria
  • Spiral-shaped bacteria
  • Gram-negative rod-shaped bacteria (correct)

What is the potential consequence of some strains of E. coli producing a toxin?

  • Mild discomfort and temporary illness
  • Increased immunity to bacterial infections
  • No impact on human health
  • Severe diarrhea and potential fatality (correct)

What is the role of interspecific horizontal gene transfer in pathogen evolution?

  • It slows down pathogen evolution
  • It accelerates the extinction of pathogens
  • It has no impact on pathogen evolution
  • It plays a role in pathogen evolution (correct)

How many virotype of E. coli are mentioned in the text?

<p>There are 5 different virotypes (A)</p> Signup and view all the answers

Which classification of diseases is mentioned in relation to E. coli?

<p>Antigenic classification (A)</p> Signup and view all the answers

What type of bacteria is Salmonella sp.?

<p>Gram-negative rod-shaped bacteria (D)</p> Signup and view all the answers

What is the potential consequence of consuming a hamburger infected with E. coli?

<p>Severe illness (C)</p> Signup and view all the answers

What is the classification of E. coli in terms of bacteria?

<p>Proteobacteria (B)</p> Signup and view all the answers

What is the name of the gene that allows E. coli O157:H7 to attach to intestinal cells?

<p>Adhesins (C)</p> Signup and view all the answers

What is the suspected reason for E. coli O157:H7's ability to cause disease?

<p>It can attach to intestinal cells (D)</p> Signup and view all the answers

What is the main method through which E. coli O157:H7 is spread to humans?

<p>Contaminated meat consumption (A)</p> Signup and view all the answers

What is a phenotype conferred by plasmids in E. coli?

<p>Antibiotic resistance (D)</p> Signup and view all the answers

What is the function of Shiga-like toxins?

<p>Damage the cells that line the walls of blood vessels (A)</p> Signup and view all the answers

What is the name of the gene responsible for E. coli attaching and effacing?

<p>eae gene (C)</p> Signup and view all the answers

How can E. coli O157:H7 be found on cattle farms?

<p>In the intestines of healthy cattle (A)</p> Signup and view all the answers

What is the suspected number of E. coli O157:H7 organisms required to cause disease?

<p>Suspected to be very small (C)</p> Signup and view all the answers

Which genera belong to the enteric bacteria within the gamma group of Proteobacteria?

<p>Escherichia, Salmonella, Proteus, Enterobacter, and Shigella (A)</p> Signup and view all the answers

Which class of E. coli is the leading bacterial cause of diarrhea in children in the developing world?

<p>ETEC (D)</p> Signup and view all the answers

Which strain of E. coli causes a syndrome identical to Shigellosis, with profuse diarrhea and high fever?

<p>EIEC (B)</p> Signup and view all the answers

Which class of E. coli causes bloody diarrhea, hemolytic-uremic syndrome, and sudden kidney failure?

<p>EHEC (D)</p> Signup and view all the answers

Which class of E. coli binds to the intestinal mucosa to cause watery diarrhea without fever?

<p>EAggEC (C)</p> Signup and view all the answers

Which class of E. coli causes diarrhea and lacks fimbriae, ST and LT toxins, but utilizes an adhesin known as intimin to bind host intestinal cells?

<p>EPEC (D)</p> Signup and view all the answers

Which statement about Escherichia coli is correct?

<p>It is an indicator of fecal pollution in water supplies, swimming beaches, and foods (C)</p> Signup and view all the answers

What are the characteristics of Escherichia coli?

<p>Gram-negative, nonsporulating rods, facultative aerobes, and most can ferment lactose (D)</p> Signup and view all the answers

At what age is the human bowel usually colonized by E. coli?

<p>Within 40 hours of birth (B)</p> Signup and view all the answers

Flashcards

Escherichia coli type

Gram-negative rod-shaped bacteria.

Toxin-producing E. coli consequence

Can cause severe diarrhea and potential fatality.

Interspecific horizontal gene transfer

It aids in pathogen evolution.

Virotypes of E. coli

There are 5 different virotypes.

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E. coli disease classification

Antigenic classification.

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Salmonella sp. type

Also a Gram-negative rod-shaped bacteria.

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E. coli in hamburgers

Can cause severe illness if infected.

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E. coli classification

Belongs to Proteobacteria.

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E. coli adhesion gene

The gene is called adhesins.

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E. coli pathogenicity reason

Ability to attach to intestinal cells.

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E. coli transmission method

Mainly through contaminated meat consumption.

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Phenotype from plasmids

Can confer antibiotic resistance.

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Shiga-like toxins function

Damage cells lining blood vessels.

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E. coli attachment gene

The eae gene is responsible.

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E. coli location on farms

Found in intestines of healthy cattle.

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E. coli dose for disease

Suspected to require very few organisms.

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Enteric bacteria genera

Includes Escherichia, Salmonella, and others.

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Diarrhea cause in children

ETEC is the leading bacteria.

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EIEC syndrome

Causes profuse diarrhea and high fever.

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EHEC symptoms

Leads to bloody diarrhea and kidney failure.

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EAggEC characteristics

Binds to intestinal mucosa causing watery diarrhea.

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EPEC binding method

Utilizes intimin to bind intestinal cells.

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E. coli as an indicator

Indicates fecal pollution in food and water.

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Escherichia coli characteristics

Gram-negative, nonsporulating rods and facultative aerobes.

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E. coli colonization age

Usually occurs within 40 hours of birth.

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Study Notes

Escherichia coli: Key Facts and Pathogenic Strains

  • Escherichia coli belongs to the enteric bacteria within the gamma group of Proteobacteria
  • Key genera include Escherichia, Salmonella, Proteus, Enterobacter, and Shigella
  • Characteristics: gram-negative, nonsporulating rods, facultative aerobes, and most can ferment lactose
  • E. coli is an indicator of fecal pollution in water supplies, swimming beaches, and foods
  • The human bowel is usually colonized by E. coli within 40 hours of birth
  • E. coli can cause intestinal diseases such as diarrhea
  • Five classes of E. coli cause diarrheal diseases: ETEC, EIEC, EHEC, EPEC, and EAggEC
  • ETEC is the leading bacterial cause of diarrhea in children in the developing world
  • EIEC infection causes a syndrome identical to Shigellosis, with profuse diarrhea and high fever
  • EPEC causes diarrhea and lacks fimbriae, ST and LT toxins, but utilizes an adhesin known as intimin to bind host intestinal cells
  • EAggEC bind to the intestinal mucosa to cause watery diarrhea without fever
  • EHEC, particularly O157:H7, causes bloody diarrhea, hemolytic-uremic syndrome, and sudden kidney failure, and produces Shiga-like toxin.

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