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Questions and Answers
Which cell is the first recognizable cell belonging to the erythropoiesis series?
Which cell is the first recognizable cell belonging to the erythropoiesis series?
- Pronormoblast (correct)
- Polychromatic/intermediate normoblast
- Orthochromatic/late normoblast
- Basophilic/early normoblast
What is the characteristic feature of CFU-E (colony forming unit-erythroid)?
What is the characteristic feature of CFU-E (colony forming unit-erythroid)?
- Significant proliferative capacity
- More eosinophilic cytoplasm
- Committed somewhat later RBC precursor (correct)
- Open nuclear chromatin pattern
What is the characteristic feature of the cytoplasm of orthochromatic/late normoblasts?
What is the characteristic feature of the cytoplasm of orthochromatic/late normoblasts?
- More basophilic with open nuclear chromatin pattern
- More eosinophilic due to hemoglobin formation (correct)
- Larger size with more basophilic cytoplasm
- Less proliferative capacity
What does BFU-E (burst forming unit-erythroid) represent in erythropoiesis?
What does BFU-E (burst forming unit-erythroid) represent in erythropoiesis?
Where does erythropoiesis take place in the body?
Where does erythropoiesis take place in the body?
Flashcards
Pronormoblast
Pronormoblast
The first recognizable cell in the erythropoiesis series.
CFU-E
CFU-E
A committed, somewhat later red blood cell precursor.
Orthochromatic Normoblast
Orthochromatic Normoblast
A late stage of erythropoiesis with a cytoplasm enriched in hemoglobin, making it appear more eosinophilic (pink).
BFU-E
BFU-E
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Where does erythropoiesis occur?
Where does erythropoiesis occur?
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Study Notes
Erythropoiesis Series
- The first recognizable cell belonging to the erythropoiesis series is the BFU-E (burst forming unit-erythroid).
CFU-E Characteristics
- The characteristic feature of CFU-E (colony forming unit-erythroid) is that it is a unipotent cell, capable of producing a single colony of mature red blood cells.
Orthochromatic/Late Normoblasts
- The characteristic feature of the cytoplasm of orthochromatic/late normoblasts is that it is basophilic, meaning it stains blue with basic dyes.
BFU-E Representation
- BFU-E (burst forming unit-erythroid) represents the earliest stage of erythropoiesis, committed to the production of mature red blood cells.
Erythropoiesis Location
- Erythropoiesis takes place in the bone marrow in the adult body.
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