5 Questions
Which cell is the first recognizable cell belonging to the erythropoiesis series?
Pronormoblast
What is the characteristic feature of CFU-E (colony forming unit-erythroid)?
Committed somewhat later RBC precursor
What is the characteristic feature of the cytoplasm of orthochromatic/late normoblasts?
More eosinophilic due to hemoglobin formation
What does BFU-E (burst forming unit-erythroid) represent in erythropoiesis?
Committed early RBC precursor with significant proliferative capacity
Where does erythropoiesis take place in the body?
Bone marrow
Study Notes
Erythropoiesis Series
- The first recognizable cell belonging to the erythropoiesis series is the BFU-E (burst forming unit-erythroid).
CFU-E Characteristics
- The characteristic feature of CFU-E (colony forming unit-erythroid) is that it is a unipotent cell, capable of producing a single colony of mature red blood cells.
Orthochromatic/Late Normoblasts
- The characteristic feature of the cytoplasm of orthochromatic/late normoblasts is that it is basophilic, meaning it stains blue with basic dyes.
BFU-E Representation
- BFU-E (burst forming unit-erythroid) represents the earliest stage of erythropoiesis, committed to the production of mature red blood cells.
Erythropoiesis Location
- Erythropoiesis takes place in the bone marrow in the adult body.
Test your knowledge of erythropoiesis and the development of red blood cells with this quiz. From pronormoblasts to mature red cells, challenge yourself to identify the different stages of erythroblast maturation and understand the process that takes place in the bone marrow.
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