Erythropoiesis: Formation of Red Blood Cells

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What is the role of CFU-E in erythropoiesis?

Undergoing amplifying divisions and maturational sequences

What is the characteristic of the pronormoblast in erythropoiesis?

Large cell size and deeply basophilic cytoplasm

Which substance is NOT needed for erythropoiesis?

Calcium

Where is 90% of Erythropoietin produced?

<p>Kidneys</p> Signup and view all the answers

What is the function of Erythropoietin in erythropoiesis?

<p>Acts on more mature committed stem cells</p> Signup and view all the answers

What is the average circulation time of RBCs?

<p>120 days</p> Signup and view all the answers

What is the significant role of ribosomes in the pronormoblast?

<p>Synthesizing gene product which is haemoglobin</p> Signup and view all the answers

Which hormone is NOT a regulator of erythropoiesis?

<p>Insulin</p> Signup and view all the answers

Which hormone plays a key role in stimulating erythropoiesis?

<p>Erythropoietin</p> Signup and view all the answers

What is the function of the CFU-E in erythropoiesis?

<p>Providing pressure for erythropoiesis</p> Signup and view all the answers

Which cell type is derived directly from the basophilic normoblast during erythropoiesis?

<p>Polychromatic Normoblast</p> Signup and view all the answers

What is the average lifespan of reticulocytes in the peripheral blood during erythropoiesis?

<p>5 days</p> Signup and view all the answers

Which cytokine is involved in the differentiation of pleuripotent stem cells during erythropoiesis?

<p>Interleukin 3</p> Signup and view all the answers

What is the site of erythropoiesis in the body?

<p>Bone marrow</p> Signup and view all the answers

What stimulates the production of erythropoietin in the body?

<p>Tissue hypoxia</p> Signup and view all the answers

What is the role of BFU-E in erythropoiesis?

<p>Responding promptly to hypoxic challenge</p> Signup and view all the answers

Which hormone acts on committed stem cells to induce proliferation, differentiation, and maturation of erythrocytes in the bone marrow?

<p>Erythropoietin</p> Signup and view all the answers

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