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Questions and Answers
What is the characteristic lesion of Erythema Multiforme?
What is the characteristic lesion of Erythema Multiforme?
- Papules
- Macules
- Bullae
- Target or iris lesions (correct)
What is the most common form of Erythema Multiforme?
What is the most common form of Erythema Multiforme?
- Lupus erythematosus
- Steven Johnson syndrome
- EM minor (correct)
- EM major
Which of the following is a cause of Erythema Multiforme?
Which of the following is a cause of Erythema Multiforme?
- Fungal infections
- Parasitic infections
- Bacterial infections
- Viral infections (correct)
What is the typical site of Erythema Multiforme lesions?
What is the typical site of Erythema Multiforme lesions?
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What is the treatment for EM minor?
What is the treatment for EM minor?
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What is the severe form of Erythema Multiforme?
What is the severe form of Erythema Multiforme?
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What is the characteristic of EM major?
What is the characteristic of EM major?
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Where is the patient with EM major typically treated?
Where is the patient with EM major typically treated?
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Study Notes
Erythema Multiforme (EM)
- Acute, self-limiting eruption of skin and mucous membranes characterized by "iris" or "target" lesions.
Etiology
- Unknown exact cause, but associated with:
- Viral infections (HSV, HCV, CMV)
- Drugs (sulphonamides, NSAID)
- X-rays
- Malignancy
- Lupus erythematosus
Clinical Picture
- Two varieties: EM minor and EM major (Steven-Johnson syndrome)
EM Minor
- Presents in 80% of cases
- Characterized by:
- Dull red macules and papules
- Typical and atypical "target" or "iris" lesions (2-3 zones)
- Affects:
- Backs of hands
- Palms
- Wrists
- Extensor aspects of elbows and knees
- Minor mucous membrane affection
EM Major (Steven-Johnson Syndrome)
- Severe form with:
- More extensive mucous membrane affection
- Lesions in the form of:
- Pustules
- Bullae
- Erosions
- Oozing
- Crusts
- Patient is generally ill
- Resolves without complications
Treatment
-
EM Minor:
- Treat underlying cause
- Antihistamines
- Antibiotics
- Topical and systemic steroids
-
EM Major:
- Burn unit care
- Care of mucous membrane lesions
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