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Questions and Answers
What is the mechanism of action of valproic acid?
What is the mechanism of action of valproic acid?
- Inhibition of voltage-sensitive sodium channels
- Inhibition of carbonic anhydrase
- Irreversible inhibition of GABA transaminase
- Blockage of T-type calcium channels and GABA transaminase (correct)
What is the effect of phenytoin and carbamazepine on the metabolism of another anticonvulsant?
What is the effect of phenytoin and carbamazepine on the metabolism of another anticonvulsant?
- They inhibit the metabolism of vigabatrin
- They induce the metabolism of valproic acid (correct)
- They inhibit the metabolism of zonisamide
- They induce the metabolism of a carbonic anhydrase inhibitor
What is the primary concern during pregnancy for women taking valproic acid?
What is the primary concern during pregnancy for women taking valproic acid?
- Risk of hepatotoxicity
- Risk of teratogenicity (correct)
- Risk of weight loss
- Risk of somnolence
What is the most common adverse effect of vigabatrin?
What is the most common adverse effect of vigabatrin?
What is the mechanism of action of zonisamide?
What is the mechanism of action of zonisamide?
What is the effect of valproic acid on the metabolism of other anticonvulsants?
What is the effect of valproic acid on the metabolism of other anticonvulsants?
What is the primary indication for vigabatrin?
What is the primary indication for vigabatrin?
What is the protein binding of valproic acid?
What is the protein binding of valproic acid?
Which of the following antiepileptic medications is known to cause oligohidrosis?
Which of the following antiepileptic medications is known to cause oligohidrosis?
What is the primary mechanism of action of Cannabidiol (Epidiolex)?
What is the primary mechanism of action of Cannabidiol (Epidiolex)?
Which of the following antiepileptic medications can decrease the efficacy of hormonal contraceptives?
Which of the following antiepileptic medications can decrease the efficacy of hormonal contraceptives?
What should be initiated in women taking antiepileptic drugs?
What should be initiated in women taking antiepileptic drugs?
Why should women who are pregnant and taking antiepileptic medications register with the North American AED Registry?
Why should women who are pregnant and taking antiepileptic medications register with the North American AED Registry?
Which of the following is a first-line medication for partial seizures?
Which of the following is a first-line medication for partial seizures?
What is a common adverse effect of Cannabidiol (Epidiolex)?
What is a common adverse effect of Cannabidiol (Epidiolex)?
Why should divalproex be avoided in women of childbearing age?
Why should divalproex be avoided in women of childbearing age?
What is the primary mechanism of action of tiagabine?
What is the primary mechanism of action of tiagabine?
Which of the following adverse effects is commonly associated with pregabalin?
Which of the following adverse effects is commonly associated with pregabalin?
What is the primary indication for phenobarbital?
What is the primary indication for phenobarbital?
Which of the following drugs is converted to phenobarbital?
Which of the following drugs is converted to phenobarbital?
What is a unique property of tiagabine's pharmacokinetics?
What is a unique property of tiagabine's pharmacokinetics?
Which of the following drugs can cause seizures in individuals without epilepsy?
Which of the following drugs can cause seizures in individuals without epilepsy?
What is the mechanism of action of phenobarbital?
What is the mechanism of action of phenobarbital?
Which of the following drugs is primarily eliminated by the kidneys?
Which of the following drugs is primarily eliminated by the kidneys?
