Enzymology Basics

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18 Questions

What is the process by which pepsinogen becomes active?

Proteolysis

What characteristic distinguishes isoenzymes from one another?

Amino acid sequence

According to the lock and key theory, what is the shape of the active site?

Fixed and unchangeable

What is the energy barrier that separates reactants from products in a chemical reaction?

Free energy of activation

What is the purpose of an enzyme in a chemical reaction?

To decrease the activation energy

What is the term for the high-energy state that occurs during formation of the product in a chemical reaction?

Transition state

What is the primary role of the active site in an enzyme molecule?

To participate in substrate binding and catalysis

What happens to the enzyme at the end of a catalyzed reaction?

It returns to its original state

What is the unit of measurement for enzyme activity?

International Units (IU)

What is the term for an enzyme that acts on one substrate only?

Absolute specificity

What is the term for the complex formed when an enzyme binds to a substrate?

Enzyme-substrate complex

How many times faster are enzyme-catalyzed reactions compared to uncatalyzed reactions?

103–108 times

What type of enzyme specificity refers to acting on a particular type of chemical bond, regardless of the rest of the molecular structure?

Linkage specificity

What is the term for an inactive enzyme that requires biochemical modification to be converted into its active form?

Zymogen

What is the purpose of compartmentalization of enzymes within specific organelles in the cell?

To isolate reactions and prevent competition

What type of enzyme specificity refers to the ability to act on a particular steric or optical isomer?

Stereochemical specificity

What is the term for enzymes that have different forms with the same catalytic activity, but differ in their physical properties?

Isoenzymes

What is the process by which a zymogen is converted into its active form?

Activation by removal of a polypeptide chain

Learn about the basics of enzyme activation, isoenzymes, and enzyme-substrate binding mechanisms, including the lock and key theory. Understand how enzymes work and their importance in biochemistry. Test your knowledge with this quiz!

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