Enzymology Basics

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Questions and Answers

What is the process by which pepsinogen becomes active?

  • Allosteric modification
  • Proteolysis (correct)
  • Hydrolysis
  • Phosphorylation

What characteristic distinguishes isoenzymes from one another?

  • Amino acid sequence (correct)
  • Substrate specificity
  • Optimal pH
  • Catalytic activity

According to the lock and key theory, what is the shape of the active site?

  • Complementary to the substrate
  • Variable and dynamic
  • Induced by the substrate
  • Fixed and unchangeable (correct)

What is the energy barrier that separates reactants from products in a chemical reaction?

<p>Free energy of activation (B)</p> Signup and view all the answers

What is the purpose of an enzyme in a chemical reaction?

<p>To decrease the activation energy (D)</p> Signup and view all the answers

What is the term for the high-energy state that occurs during formation of the product in a chemical reaction?

<p>Transition state (B)</p> Signup and view all the answers

What is the primary role of the active site in an enzyme molecule?

<p>To participate in substrate binding and catalysis (A)</p> Signup and view all the answers

What happens to the enzyme at the end of a catalyzed reaction?

<p>It returns to its original state (B)</p> Signup and view all the answers

What is the unit of measurement for enzyme activity?

<p>International Units (IU) (A)</p> Signup and view all the answers

What is the term for an enzyme that acts on one substrate only?

<p>Absolute specificity (C)</p> Signup and view all the answers

What is the term for the complex formed when an enzyme binds to a substrate?

<p>Enzyme-substrate complex (D)</p> Signup and view all the answers

How many times faster are enzyme-catalyzed reactions compared to uncatalyzed reactions?

<p>103–108 times (C)</p> Signup and view all the answers

What type of enzyme specificity refers to acting on a particular type of chemical bond, regardless of the rest of the molecular structure?

<p>Linkage specificity (C)</p> Signup and view all the answers

What is the term for an inactive enzyme that requires biochemical modification to be converted into its active form?

<p>Zymogen (C)</p> Signup and view all the answers

What is the purpose of compartmentalization of enzymes within specific organelles in the cell?

<p>To isolate reactions and prevent competition (C)</p> Signup and view all the answers

What type of enzyme specificity refers to the ability to act on a particular steric or optical isomer?

<p>Stereochemical specificity (B)</p> Signup and view all the answers

What is the term for enzymes that have different forms with the same catalytic activity, but differ in their physical properties?

<p>Isoenzymes (C)</p> Signup and view all the answers

What is the process by which a zymogen is converted into its active form?

<p>Activation by removal of a polypeptide chain (A)</p> Signup and view all the answers

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