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Questions and Answers
What is the main way enzymes reduce the activation energy?
What is the main way enzymes reduce the activation energy?
Which model states that the enzyme's active site is exactly the correct shape for the substrate to bind to?
Which model states that the enzyme's active site is exactly the correct shape for the substrate to bind to?
What is the point of highest energy on the progress of a reaction curve called?
What is the point of highest energy on the progress of a reaction curve called?
Which type of reaction do most enzymes catalyze?
Which type of reaction do most enzymes catalyze?
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What does the induced fit model propose?
What does the induced fit model propose?
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What ratio is used to obtain rate enhancement?
What ratio is used to obtain rate enhancement?
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What occurs at the point of highest energy on the progress of a reaction curve?
What occurs at the point of highest energy on the progress of a reaction curve?
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What do enzymes primarily catalyse?
What do enzymes primarily catalyse?
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What does substrate specificity refer to?
What does substrate specificity refer to?
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What type of model suggests that small molecules with a similar shape to part of the substrate cannot bind?
What type of model suggests that small molecules with a similar shape to part of the substrate cannot bind?
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Which type of inhibitor forms covalent interactions with the enzyme and does not come off once it binds?
Which type of inhibitor forms covalent interactions with the enzyme and does not come off once it binds?
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In which process does a molecule become irreversibly bound and inactivate the enzyme?
In which process does a molecule become irreversibly bound and inactivate the enzyme?
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What is the measure of affinity between enzyme and inhibitor in competitive inhibition?
What is the measure of affinity between enzyme and inhibitor in competitive inhibition?
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Which type of inhibitor binds at the same site as the substrate and blocks access for the substrate?
Which type of inhibitor binds at the same site as the substrate and blocks access for the substrate?
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Which type of inhibitor induces a conformational change in the enzyme and prevents catalysis?
Which type of inhibitor induces a conformational change in the enzyme and prevents catalysis?
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Which plot can be used to distinguish between competitive and non-competitive inhibitors?
Which plot can be used to distinguish between competitive and non-competitive inhibitors?
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Which molecule is an example of a suicide inhibitor?
Which molecule is an example of a suicide inhibitor?
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Which enzyme is methotrexate a competitive inhibitor for?
Which enzyme is methotrexate a competitive inhibitor for?
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Enzymes are generally smaller than their substrates.
Enzymes are generally smaller than their substrates.
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The lock and key model suggests that small molecules with a similar shape to part of the substrate cannot bind.
The lock and key model suggests that small molecules with a similar shape to part of the substrate cannot bind.
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Enzymes can catalyze multiple types of reactions.
Enzymes can catalyze multiple types of reactions.
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The induced fit model proposes that the substrate induces a change in confirmation so it can fit into the active site of the enzyme.
The induced fit model proposes that the substrate induces a change in confirmation so it can fit into the active site of the enzyme.
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The main way enzymes reduce the activation energy is by increasing the energy of the transition state.
The main way enzymes reduce the activation energy is by increasing the energy of the transition state.
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Non-competitive inhibitors do not affect the Vmax of an enzyme
Non-competitive inhibitors do not affect the Vmax of an enzyme
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Sarin is an example of a reversible inhibitor of acetylcholinesterase
Sarin is an example of a reversible inhibitor of acetylcholinesterase
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Reversible inhibitors can be removed from the enzyme by dialysis due to covalent interactions
Reversible inhibitors can be removed from the enzyme by dialysis due to covalent interactions
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Methotrexate is a non-competitive inhibitor for the enzyme dihydrofolate reductase
Methotrexate is a non-competitive inhibitor for the enzyme dihydrofolate reductase
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The Lineweaver-Burk plot can be used to distinguish between competitive and non-competitive inhibitors
The Lineweaver-Burk plot can be used to distinguish between competitive and non-competitive inhibitors
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