20 Questions
Which domain of enzyme coupled receptors has intrinsic enzyme activity or associates with an enzyme?
Cytosolic domain
What is the main characteristic of enzyme coupled receptors?
They have transmembrane domains
What is the function of receptor tyrosine kinases (RTKs)?
Signal transduction pathways activation
What is the role of non-receptor tyrosine kinases (NRTKs)?
Cell cycle control
What is the main function of receptor tyrosine kinases (RTKs)?
Activation and phosphorylation of the receptor C-terminal tail
Which cellular processes are regulated by receptor tyrosine kinases (RTKs)?
Cell proliferation and differentiation
How are RTKs activated in normal physiology?
Through formation of inter-molecular dimerization in the presence of ligands
What is the significance of mutations in RTKs and aberrant activation of their intracellular signaling pathways?
Association with several diseases including cancers, diabetes, inflammation, and arteriosclerosis
What does ligand binding lead to in the context of RTKs?
Dimerization of the receptor and stimulation of kinase activity
What happens when RTKs are overexpressed as a result of genomic amplification?
Increased local concentration of receptor Activated RTKs
Which subtopic of biology focuses on the transmission of genetic information from one generation to the next?
Genetics
What is the primary carrier of genetic information in living organisms?
DNA
Which organelle within cells has its own genetic system essential for the proper functioning of cells?
Chloroplasts
What is the main focus of physiology?
Understanding the systematic and coordinated functioning of body parts and systems
What is the natural phenomenon that contributes to the diversity of life by leading to differences in traits such as physical appearance, behavior, or susceptibility to certain diseases?
Genetic Variation
What is the study of the structure, function, and interactions of cells called?
Cell Biology
Which aspect is NOT included in the study of biology?
Meteorology
What are the basic structural and functional units of life?
Cells
Which mechanism do cells use to communicate with each other?
Anaerobic respiration
What ensures the proper functioning of an organism in a constantly changing environment?
Maintaining a stable internal environment by cells
Test your knowledge about enzyme coupled receptors, transmembrane proteins with ligand binding domains on the outer surface of the membrane and intrinsic enzyme activity in the cytosolic domain.
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