Enzyme Coupled Receptors

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Which domain of enzyme coupled receptors has intrinsic enzyme activity or associates with an enzyme?

Ligand binding domain

Extracellular domain

Transmembrane domain

Cytosolic domain (correct)

What is the main characteristic of enzyme coupled receptors?

They have transmembrane domains (correct)

They do not associate with any enzymes

They have ligand binding domain on the inner surface of the membrane

They are intracellular proteins

What is the function of receptor tyrosine kinases (RTKs)?

Metabolism regulation

Cell membrane stabilization

Regulation of transcription factors

Signal transduction pathways activation (correct)

What is the role of non-receptor tyrosine kinases (NRTKs)?

Cell cycle control Signup and view all the answers

What is the main function of receptor tyrosine kinases (RTKs)?

Activation and phosphorylation of the receptor C-terminal tail Signup and view all the answers

Which cellular processes are regulated by receptor tyrosine kinases (RTKs)?

Cell proliferation and differentiation Signup and view all the answers

How are RTKs activated in normal physiology?

Through formation of inter-molecular dimerization in the presence of ligands Signup and view all the answers

What is the significance of mutations in RTKs and aberrant activation of their intracellular signaling pathways?

Association with several diseases including cancers, diabetes, inflammation, and arteriosclerosis Signup and view all the answers

What does ligand binding lead to in the context of RTKs?

Dimerization of the receptor and stimulation of kinase activity Signup and view all the answers

What happens when RTKs are overexpressed as a result of genomic amplification?

Increased local concentration of receptor Activated RTKs Signup and view all the answers

Which subtopic of biology focuses on the transmission of genetic information from one generation to the next?

Genetics Signup and view all the answers

What is the primary carrier of genetic information in living organisms?

DNA Signup and view all the answers

Which organelle within cells has its own genetic system essential for the proper functioning of cells?

Chloroplasts Signup and view all the answers

What is the main focus of physiology?

Understanding the systematic and coordinated functioning of body parts and systems Signup and view all the answers

What is the natural phenomenon that contributes to the diversity of life by leading to differences in traits such as physical appearance, behavior, or susceptibility to certain diseases?

Genetic Variation Signup and view all the answers

What is the study of the structure, function, and interactions of cells called?

Cell Biology Signup and view all the answers

Which aspect is NOT included in the study of biology?

Meteorology Signup and view all the answers

What are the basic structural and functional units of life?

Cells Signup and view all the answers

Which mechanism do cells use to communicate with each other?

Anaerobic respiration Signup and view all the answers

What ensures the proper functioning of an organism in a constantly changing environment?

Maintaining a stable internal environment by cells Signup and view all the answers