Podcast
Questions and Answers
What term describes a chemical species with an affinity for a positive charge and acts as an electron donor?
What term describes a chemical species with an affinity for a positive charge and acts as an electron donor?
- Coenzyme
- Nucleophile (correct)
- Prosthetic group
- Electrophile
Which type of effector involves the substrate binding to the allosteric site in an enzyme?
Which type of effector involves the substrate binding to the allosteric site in an enzyme?
- Heterotropic effector
- Homotropic effector (correct)
- Cofactor
- NAD+
What is the term for a small organic molecule required for enzyme activity?
What is the term for a small organic molecule required for enzyme activity?
- Nucleophile
- Coenzyme (correct)
- Prosthetic group
- Cofactor
In covalent catalysis, what does the enzyme form temporarily with the substrate to catalyze the reaction?
In covalent catalysis, what does the enzyme form temporarily with the substrate to catalyze the reaction?
What term describes the released energy when weak interactions are formed between the enzyme and substrate, promoting specificity?
What term describes the released energy when weak interactions are formed between the enzyme and substrate, promoting specificity?
Which type of effector involves a ligand binding to the allosteric site that is different from the substrate?
Which type of effector involves a ligand binding to the allosteric site that is different from the substrate?
How is metal ion catalysis involved in nucleophile formation?
How is metal ion catalysis involved in nucleophile formation?
In NMP kinase, what is the purpose of having a divalent ion-bound nucleotide as the true substrate?
In NMP kinase, what is the purpose of having a divalent ion-bound nucleotide as the true substrate?
How does proximity aid in catalysis in NMP kinase?
How does proximity aid in catalysis in NMP kinase?
What is the role of the P-loop in NMP kinase activation?
What is the role of the P-loop in NMP kinase activation?
What effect does metal ion catalysis have on serine proteases like chymotrypsin?
What effect does metal ion catalysis have on serine proteases like chymotrypsin?
How does metal ion catalysis contribute to enzyme function in restriction endonucleases?
How does metal ion catalysis contribute to enzyme function in restriction endonucleases?
What role does carbonic anhydrase play in the reaction of CO2 to HCO3-?
What role does carbonic anhydrase play in the reaction of CO2 to HCO3-?
How does Zn2+ contribute to the reaction catalyzed by carbonic anhydrase?
How does Zn2+ contribute to the reaction catalyzed by carbonic anhydrase?
What is the mechanism by which His 64 facilitates the reaction in carbonic anhydrase?
What is the mechanism by which His 64 facilitates the reaction in carbonic anhydrase?
In carbonic anhydrase, what is the function of OH-?
In carbonic anhydrase, what is the function of OH-?
What is the main impact of carbonic anhydrase on the speed of the reaction?
What is the main impact of carbonic anhydrase on the speed of the reaction?
How does carbonic anhydrase promote the regeneration of its active site?
How does carbonic anhydrase promote the regeneration of its active site?