Podcast
Questions and Answers
What is the catalytic strategy used by carbonic anhydrases?
What is the catalytic strategy used by carbonic anhydrases?
- Acid-Base Catalysis
- Charge Complementarity
- Covalent Catalysis
- Approximation (correct)
What metal ion is universally used in the family prevalence of carbonic anhydrases?
What metal ion is universally used in the family prevalence of carbonic anhydrases?
- Zinc (correct)
- Cadmium
- Cobalt
- Iron
How many families of carbonic anhydrases have been discovered?
How many families of carbonic anhydrases have been discovered?
- 5
- 10
- 15
- 8 (correct)
What is the main physiological relevance of carbonic anhydrases?
What is the main physiological relevance of carbonic anhydrases?
Which enzyme utilizes the catalytic strategy of Approximation?
Which enzyme utilizes the catalytic strategy of Approximation?
What is the steady state assumption?
What is the steady state assumption?
What does the equilibrium constant Km represent?
What does the equilibrium constant Km represent?
In the equation Δ𝐸·𝑆 = 𝑘1 𝐸 𝑆 − 𝑘−1 𝐸·𝑆 − 𝑘2 𝐸·𝑆 = 0, what does Δ𝐸·𝑆 represent?
In the equation Δ𝐸·𝑆 = 𝑘1 𝐸 𝑆 − 𝑘−1 𝐸·𝑆 − 𝑘2 𝐸·𝑆 = 0, what does Δ𝐸·𝑆 represent?
How does knowing [E]T and [E·S] help in understanding enzyme kinetics?
How does knowing [E]T and [E·S] help in understanding enzyme kinetics?
What correction factor can be used to correct for osmolarity deviations?
What correction factor can be used to correct for osmolarity deviations?
What is the main contributor to the osmolarity of the interstitial fluid and plasma?
What is the main contributor to the osmolarity of the interstitial fluid and plasma?
What causes the slight difference between plasma and interstitial fluid osmolarity?
What causes the slight difference between plasma and interstitial fluid osmolarity?
What maintains about 20 mm Hg greater pressure in the capillaries than in the surrounding interstitial spaces?
What maintains about 20 mm Hg greater pressure in the capillaries than in the surrounding interstitial spaces?
What can cause a slight decrease in the osmotic activity of dissolved substances?
What can cause a slight decrease in the osmotic activity of dissolved substances?
What happens with small changes in the concentration of solutes in the extracellular fluid?
What happens with small changes in the concentration of solutes in the extracellular fluid?
About how much of the total osmolarity of intracellular fluid is due to potassium ions?
About how much of the total osmolarity of intracellular fluid is due to potassium ions?
What is used to express corrected osmolar activities of plasma, interstitial fluid, and intracellular fluid?
What is used to express corrected osmolar activities of plasma, interstitial fluid, and intracellular fluid?
What effect does urea have on intracellular volume under steady-state conditions?
What effect does urea have on intracellular volume under steady-state conditions?
Why is complete osmotic equilibrium not immediately achieved between the intracellular and extracellular compartments throughout the whole body?
Why is complete osmotic equilibrium not immediately achieved between the intracellular and extracellular compartments throughout the whole body?
What are some factors that can cause extracellular and intracellular volumes to change?
What are some factors that can cause extracellular and intracellular volumes to change?
What is the timeframe within which differences in osmolarities between intracellular and extracellular compartments are usually corrected?
What is the timeframe within which differences in osmolarities between intracellular and extracellular compartments are usually corrected?
How does the transfer of fluid across the cell membrane contribute to the correction of differences in osmolarities?
How does the transfer of fluid across the cell membrane contribute to the correction of differences in osmolarities?
What is the primary reason for the delay in achieving complete osmotic equilibrium between the intracellular and extracellular compartments?
What is the primary reason for the delay in achieving complete osmotic equilibrium between the intracellular and extracellular compartments?
What happens to the concentrations of highly permeating substances like urea in the intracellular and extracellular fluids over time?
What happens to the concentrations of highly permeating substances like urea in the intracellular and extracellular fluids over time?
What is the immediate effect of highly permeating substances like urea on fluid volume between intracellular and extracellular fluids?
What is the immediate effect of highly permeating substances like urea on fluid volume between intracellular and extracellular fluids?
What is the relationship between pH and H+ concentration?
What is the relationship between pH and H+ concentration?
What is the normal pH of arterial blood?
What is the normal pH of arterial blood?
At what pH would a person be considered to have acidemia?
At what pH would a person be considered to have acidemia?
Why is it customary to express H+ concentration on a logarithm scale using pH units?
Why is it customary to express H+ concentration on a logarithm scale using pH units?
What would a high pH correspond to in terms of H+ concentration?
What would a high pH correspond to in terms of H+ concentration?
What is the pH of venous blood and interstitial fluids?
What is the pH of venous blood and interstitial fluids?
What does a low pH correspond to in terms of H+ concentration?
What does a low pH correspond to in terms of H+ concentration?
What does the formula pH=-log[H+] indicate about the relationship between pH and H+ concentration?
What does the formula pH=-log[H+] indicate about the relationship between pH and H+ concentration?
What is the primary purpose of the body fluid buffers?
What is the primary purpose of the body fluid buffers?
What is the bicarbonate buffer system composed of?
What is the bicarbonate buffer system composed of?
Where is carbonic anhydrase especially abundant in the body?
Where is carbonic anhydrase especially abundant in the body?
What happens to the daily production and ingestion of acids without buffering?
What happens to the daily production and ingestion of acids without buffering?
What is required for the formation of H2CO3 in the body?
What is required for the formation of H2CO3 in the body?
Which buffer system is quantitatively most important in the extracellular fluid?
Which buffer system is quantitatively most important in the extracellular fluid?
What does ingestion or production of about 80 milliequivalents of H+ each day by metabolism imply?
What does ingestion or production of about 80 milliequivalents of H+ each day by metabolism imply?
What happens to the H2CO3 formation if carbonic anhydrase is absent?
What happens to the H2CO3 formation if carbonic anhydrase is absent?
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