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Environmental Toxicology and Antidotal Therapy

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Environmental Toxicology and Antidotal Therapy

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Questions and Answers

Which of the following are signs of cholinergic syndromes?

Hypertension and tachycardia

Hyperthermia and excessive sweating

Hypotension and bradycardia

Muscle twitching and weakness (correct)

What is the treatment for cholinergic syndromes caused by organophosphates?

Physostigmine and atropine

Atropine only

Pralidoxime (2-PAM) only

Pralidoxime (2-PAM) and atropine (correct)

Which non-specific antidote limits drug absorption but is not as efficacious if the drug is rapidly absorbed?

Activated charcoal (correct)

Syrup of ipecac

Whole-bowel irrigation

Gastric lavage

Which toxic syndrome is characterized by signs such as hypotension, bradycardia, coma, respiratory depression, miosis, and CNS depression?

Opiates Signup and view all the answers

What is the common cause of sympathomimetic toxic syndrome?

Cocaine Signup and view all the answers

Which specific antidote may be used for the treatment of non-opiate toxic syndrome?

Flumazenil Signup and view all the answers

What is the recommended treatment for sympathomimetic toxic syndrome with seizures?

Benzodiazepines Signup and view all the answers

What is the meaning of LD50 in toxicology?

The dose that produces death in 50% of treated animals Signup and view all the answers

Which of the following is an example of a specific antidote in toxicology?

British Anti-Lewisite; BAL (Dimercaprol) Signup and view all the answers

What does NOAEL stand for in toxicology?

No Observed Adverse Effect Level Signup and view all the answers