Entamoeba histolytica Pathogenesis
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Questions and Answers

What are the most important factors affecting the ability of Entamoeba histolytica to produce pathological changes?

  • Virulence of the infective strain, host resistance, host nutritional status, and bacterial infection of the colon (correct)
  • Infective strain of the parasite, host immunity, host age, and bacterial infection of the colon
  • Parasite load, host genetic makeup, host vaccination status, and bacterial infection of the colon
  • Parasite strain, host diet, host exercise level, and bacterial infection of the colon
  • Which areas in the colon are most affected by Entamoeba histolytica?

  • Caecum, right and left colonic flexures, and sigmoid colon (correct)
  • Sigmoid colon, ascending colon, descending colon, and transverse colon
  • Appendix, ascending colon, descending colon, and rectum
  • Rectum, ascending colon, transverse colon, and descending colon
  • What do pathogenic trophozoites of Entamoeba histolytica secrete to penetrate the epithelial lining of the large intestine?

  • Lytic enzymes (correct)
  • Inflammatory cytokines
  • Digestive acids
  • Antigenic proteins
  • What is produced when necrotic contents carrying tissue forms are discharged in stools?

    <p>Flask-shaped ulcers</p> Signup and view all the answers

    What complication can occur if amoebiasis extends to the appendix?

    <p>Amoebic appendicitis</p> Signup and view all the answers

    Study Notes

    Entamoeba histolytica Pathogenesis

    • The ability of Entamoeba histolytica to produce pathological changes is influenced by factors such as the parasite's virulence, the host's immune status, and the presence of bacterial flora in the gut.

    Affected Areas in the Colon

    • The caecum and ascending colon are the most commonly affected areas by Entamoeba histolytica.

    Penetration of Epithelial Lining

    • Pathogenic trophozoites of Entamoeba histolytica secrete cysteine proteases to penetrate the epithelial lining of the large intestine.

    Characteristics of Necrotic Contents

    • When necrotic contents carrying tissue forms are discharged in stools, they produce a characteristic "anchovy sauce" appearance.

    Complications of Amoebiasis

    • If amoebiasis extends to the appendix, it can lead to acute appendicitis, a potentially life-threatening complication.

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    Description

    Test your knowledge of the factors influencing the ability of Entamoeba histolytica to produce pathological changes and the most affected areas in the colon. Learn about the virulence of infective strains, host resistance, nutritional status, and bacterial infections.

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