12 Questions
What is the characteristic of the abscess in amoebic liver abscess?
Anchovy paste consistency
What is the primary mode of transmission of Entamoeba histolytica?
Contaminated water ingestion
What is the name of the antibiotic commonly used to treat amoebiasis?
Metronidazole
What is the characteristic of the ulcerations caused by Entamoeba histolytica in the colon?
Flask-shaped
What is the primary site of involvement in amoebic liver abscess?
Right lobe
What is the purpose of the stool O&P test?
To detect trophozoites or cysts in the stool
What is the common site of involvement in amoebic liver abscess?
Right lobe of the liver
What is the appearance of the ulcers caused by Entamoeba histolytica in the colon?
Flask-shaped
What is the purpose of the ELISA antigen test in the diagnosis of amoebiasis?
To detect antibodies against Entamoeba histolytica
What is the mode of transmission of Entamoeba histolytica?
Through contaminated food and water
What is the characteristic of the stool in intestinal amebiasis?
Presence of cysts or trophozoites
What is the antibiotic of choice for treating amoebiasis?
Metronidazole
Study Notes
Entamoeba Histolytica Infection
- Entamoeba histolytica causes intestinal amebiasis, which can lead to bloody diarrhea, characterized by red stools.
- Infection occurs through the ingestion of contaminated water containing the cyst form of the parasite.
Life Cycle
- The parasite has two main life cycle stages: cyst and trophozoite.
- Cyst form is ingested from contaminated water, and gastric acid in the stomach stimulates the release of trophozoites.
- Trophozoites are released in the duodenum and divide by binary fission.
- Trophozoites and cysts are passed in feces, which can spread the infection via contaminated water.
Clinical Features
- Liver abscess is a common complication, typically occurring in the right lobe of the liver.
- Patients with liver abscess may experience RUQ pain, tenderness, and an enlarged liver.
- The abscess has a characteristic "anchovy paste" consistency.
- Intestinal amebiasis can cause ulcerations along the colon, leading to flask-shaped ulcers.
- Stool O&P test may reveal the presence of cysts or trophozoites, with phagocytosed RBCs.
Diagnosis and Treatment
- Diagnosis can be made using an ELISA antigen test or serology.
- Metronidazole is a commonly used antibiotic for treating Entamoeba histolytica infection.
- Other drugs that work in the lumen of the intestine include paromycin and iodoquinol.
- Adherence to the large intestine is mediated by galactose targeting adherence protein (lectin), and amebopore cytotoxin causes inflammation and tissue damage.
Entamoeba Histolytica Infection
- Entamoeba histolytica causes intestinal amebiasis, which can lead to bloody diarrhea, characterized by red stools.
- Infection occurs through the ingestion of contaminated water containing the cyst form of the parasite.
Life Cycle
- The parasite has two main life cycle stages: cyst and trophozoite.
- Cyst form is ingested from contaminated water, and gastric acid in the stomach stimulates the release of trophozoites.
- Trophozoites are released in the duodenum and divide by binary fission.
- Trophozoites and cysts are passed in feces, which can spread the infection via contaminated water.
Clinical Features
- Liver abscess is a common complication, typically occurring in the right lobe of the liver.
- Patients with liver abscess may experience RUQ pain, tenderness, and an enlarged liver.
- The abscess has a characteristic "anchovy paste" consistency.
- Intestinal amebiasis can cause ulcerations along the colon, leading to flask-shaped ulcers.
- Stool O&P test may reveal the presence of cysts or trophozoites, with phagocytosed RBCs.
Diagnosis and Treatment
- Diagnosis can be made using an ELISA antigen test or serology.
- Metronidazole is a commonly used antibiotic for treating Entamoeba histolytica infection.
- Other drugs that work in the lumen of the intestine include paromycin and iodoquinol.
- Adherence to the large intestine is mediated by galactose targeting adherence protein (lectin), and amebopore cytotoxin causes inflammation and tissue damage.
Quiz about Entamoeba Histolytica, a parasite that causes intestinal and extraintestinal amoebiasis. Learn about its life cycle, symptoms, and transmission.
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