Entamoeba histolytica Overview
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Questions and Answers

Which characteristic best describes the cyst stage of Entamoeba histolytica?

  • It is the actively feeding and reproducing form.
  • It is resistant to environmental conditions and infective. (correct)
  • It primarily causes intestinal symptoms upon ingestion.
  • It requires optimal environmental conditions to survive.
  • What is the primary method for diagnosing intestinal amebiasis?

  • Radiological imaging of the abdomen.
  • Stool examination using trichrome stain. (correct)
  • Liver function tests.
  • Direct PCR of intestinal biopsy.
  • Which statement about the clinical manifestations of Entamoeba histolytica is correct?

  • All infections present with bloody diarrhea.
  • Amebic dysentery is characterized only by abdominal pain.
  • Abdominal flatulence is a hallmark of intestinal amebiasis.
  • Liver abscess is the most common extraintestinal complication. (correct)
  • What role do lectins play in the pathogenesis of Entamoeba histolytica?

    <p>They facilitate adherence to the intestinal mucosa.</p> Signup and view all the answers

    Which method is effective in preventing infection by Entamoeba histolytica?

    <p>Practicing handwashing before meals.</p> Signup and view all the answers

    Study Notes

    Entamoeba histolytica: Key Characteristics

    • Entamoeba histolytica is a protozoan parasite.
    • Transmission occurs through the fecal-oral route, via ingested cysts in contaminated food or water.
    • Two primary life cycle stages exist: trophozoites (actively feeding and reproducing) and cysts (infective, resistant to environmental conditions).

    Pathogenesis and Symptoms

    • Entamoeba histolytica adheres to intestinal mucosa using lectins.
    • It invades tissues, releasing proteolytic enzymes.
    • Ulcer formation, often flask-shaped, is a characteristic feature.
    • Extraintestinal spread is possible, affecting organs like the liver, lungs, and brain.
    • Infection can be asymptomatic or manifest as intestinal or extraintestinal disease.
    • Intestinal amebiasis can present as amebic dysentery (bloody diarrhea, abdominal pain, fever) or amebic colitis (diarrhea, abdominal pain, flatulence).
    • Liver abscess is the most common extraintestinal complication.

    Diagnosis and Treatment

    • Microscopy of stool samples (wet mount, iodine, trichrome stains) identifies trophozoites and cysts.
    • Serological tests measure antibodies.
    • Metronidazole targets trophozoites, and paromomycin targets cysts.

    Prevention

    • Proper sanitation is crucial, including sewage disposal and safe water.
    • Personal hygiene through handwashing is essential.
    • Thorough food preparation prevents infection.

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    Description

    This quiz covers the key characteristics, pathogenesis, and symptoms associated with Entamoeba histolytica. Explore its life cycle stages, modes of transmission, and possible complications, including intestinal and extraintestinal diseases. Test your knowledge on diagnosis and treatment methods for this protozoan parasite.

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