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Endogenous Opioid Neurotransmitters Quiz

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Endogenous Opioid Neurotransmitters Quiz

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Questions and Answers

Which neurotransmitters constitute the pain inhibiting system in the spinal cord and brain?

Endorphins, Dynorphins, Enkephalins (correct)

Dopamine, Serotonin, Acetylcholine

Glutamate, GABA, Glycine

Epinephrine, Norepinephrine, Substance P

Which opioid receptor type is relatively selective for clinically used opioids?

delta (δ)

kappa (ҝ)

sigma (σ)

mu (µ) (correct)

What is the main effect of opioids on presynaptic nerve fibers?

Decrease in K+ efflux

Decrease in Ca++ influx (correct)

Increase in K+ efflux

Increase in Ca++ influx

What is the state in which painful stimuli are moderated, although perceived but felt no more painful?

Analgesia Signup and view all the answers

Which type of receptors do opioids activate post-synaptically?

Mu (µ) Signup and view all the answers

Name three endogenous opioid neurotransmitters that constitute the pain inhibiting system in the spinal cord and brain.

Endorphins, Dynorphins, Enkephalins Signup and view all the answers

What is analgesia?

Analgesia is a state in which painful stimuli are moderated, although perceived, but felt no more painful. Signup and view all the answers

What are the three types of opioid receptors?

mu (µ), delta (δ), kappa (ҝ) Signup and view all the answers

Which opioid receptor type are most clinically used opioids relatively selective for?

mu (µ) receptor Signup and view all the answers

What is the mechanism of action of opioids on presynaptic nerve fibers?

On binding to receptors at presynaptic nerve fibers, opioids cause a decrease in Ca++ influx which results in a decrease in the release of excitatory neurotransmitters like glutamate. Signup and view all the answers