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Questions and Answers
Which neurotransmitters constitute the pain inhibiting system in the spinal cord and brain?
Which neurotransmitters constitute the pain inhibiting system in the spinal cord and brain?
- Endorphins, Dynorphins, Enkephalins (correct)
- Dopamine, Serotonin, Acetylcholine
- Glutamate, GABA, Glycine
- Epinephrine, Norepinephrine, Substance P
Which opioid receptor type is relatively selective for clinically used opioids?
Which opioid receptor type is relatively selective for clinically used opioids?
- delta (δ)
- kappa (ҝ)
- sigma (σ)
- mu (µ) (correct)
What is the main effect of opioids on presynaptic nerve fibers?
What is the main effect of opioids on presynaptic nerve fibers?
- Decrease in K+ efflux
- Decrease in Ca++ influx (correct)
- Increase in K+ efflux
- Increase in Ca++ influx
What is the state in which painful stimuli are moderated, although perceived but felt no more painful?
What is the state in which painful stimuli are moderated, although perceived but felt no more painful?
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Which type of receptors do opioids activate post-synaptically?
Which type of receptors do opioids activate post-synaptically?
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Name three endogenous opioid neurotransmitters that constitute the pain inhibiting system in the spinal cord and brain.
Name three endogenous opioid neurotransmitters that constitute the pain inhibiting system in the spinal cord and brain.
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What is analgesia?
What is analgesia?
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What are the three types of opioid receptors?
What are the three types of opioid receptors?
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Which opioid receptor type are most clinically used opioids relatively selective for?
Which opioid receptor type are most clinically used opioids relatively selective for?
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What is the mechanism of action of opioids on presynaptic nerve fibers?
What is the mechanism of action of opioids on presynaptic nerve fibers?
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