Endocrinology Chapter Overview
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Questions and Answers

The medulla is composed of closely associated glands.

False

The pituitary gland is an example of a pure endocrine entity.

True

Hormones are secreted directly into the lymphatic system only.

False

Only a large quantity of hormones is necessary to influence target organs.

<p>False</p> Signup and view all the answers

Endocrine components of the body can form part of any of the three primary germ layers.

<p>True</p> Signup and view all the answers

Basophils contain more numerous granules than acidophils.

<p>False</p> Signup and view all the answers

Chromophobes are best identified by the Periodic Acid-Schiff (PAS) technique.

<p>True</p> Signup and view all the answers

Methylene blue stains the granules of chromophobes poorly.

<p>False</p> Signup and view all the answers

Basophils can be identified by the aniline blue stain.

<p>True</p> Signup and view all the answers

There are at least 6 confirmed cell types in the pars distalis identified by immunohistochemistry.

<p>True</p> Signup and view all the answers

Parathormone production is controlled by other endocrine glands.

<p>False</p> Signup and view all the answers

Oxyphil cells have a known secretory role in the body.

<p>False</p> Signup and view all the answers

Only about two-thirds of chief cells are actively synthesizing parathormone in a normal adult.

<p>False</p> Signup and view all the answers

The adrenal glands are located at the upper poles of the kidneys.

<p>True</p> Signup and view all the answers

Active chief cells stain lighter than less active chief cells in light microscopy.

<p>False</p> Signup and view all the answers

Thyrotropes stain with aldehyde fuchsin and secrete thyrotropic hormone (TSH).

<p>True</p> Signup and view all the answers

Gonadotropes stain positively with aldehyde fuchsin and secrete gonadotropins.

<p>False</p> Signup and view all the answers

Corticotropes are included in the group of cells that secrete thyroid-stimulating hormones.

<p>False</p> Signup and view all the answers

The cell boundaries of thyrotropes are easily visible in ordinary preparations.

<p>False</p> Signup and view all the answers

The cytoplasm of thyrotropes contains specific granules that are located in the peripheral cytoplasm.

<p>False</p> Signup and view all the answers

Neurons in the adrenal medulla can convert norepinephrine (NE) to epinephrine (EPI).

<p>False</p> Signup and view all the answers

The adrenal medulla secretes hormones into the blood that help an individual respond to emergency situations.

<p>True</p> Signup and view all the answers

Epinephrine primarily acts as a vasodilator with significant effects on metabolism.

<p>False</p> Signup and view all the answers

Cells of the adrenal cortex have a greater capacity for regeneration than those of the adrenal medulla.

<p>True</p> Signup and view all the answers

The adrenal cortex is responsible for maintaining the body's fluid and electrolyte balance.

<p>True</p> Signup and view all the answers

The adrenal glands receive blood supply from two arteries only.

<p>False</p> Signup and view all the answers

The medulla of the adrenal glands has a dual blood supply.

<p>True</p> Signup and view all the answers

The zona reticularis is known to have a well-developed Golgi complex.

<p>True</p> Signup and view all the answers

There is no venous system in the cortex of the adrenal glands.

<p>True</p> Signup and view all the answers

The adrenal medulla contains a high amount of glycogen particles.

<p>False</p> Signup and view all the answers

Catecholamine primarily includes epinephrine in the adrenal medulla.

<p>False</p> Signup and view all the answers

The cortical sinusoids do not anastomose with the medulla's capillary bed.

<p>False</p> Signup and view all the answers

The adrenal glands have a highly vascular structure.

<p>True</p> Signup and view all the answers

Study Notes

Endocrine System Outline

  • Composed mainly of ductless glands releasing hormones directly into the blood or lymph.
  • Three primary germ layers (ectoderm, mesoderm, endoderm) give rise to different endocrine components.
  • Endocrine components can be separate glands, scattered masses within exocrine glands, or isolated endocrine cells within other organs.

Primary Germ Layers

  • Ectoderm: Hypophysis, adrenal medulla, Chromaffin bodies
  • Mesoderm: Adrenal cortex, testes, ovaries
  • Endoderm: Thyroid, parathyroid, pancreatic islets of Langerhans

Hormone Classes

  • Steroid hormones: Adrenocortical hormones (adrenal cortex), testosterone (testes), estrogen and progesterone (ovaries)
  • Protein hormones; prolactin, insulin (hypophysis, pancreas, thyroid, parathyroid)
  • Amino acid analogues and derivatives; thyroxine, norepinephrine (thyroid, adrenal medulla)

Endocrine System Functions

  • Hormones have a specific effect on target organs, often stimulating or activating or sometimes inhibiting.
  • Target cells contain receptors affecting specific physiological responses.
  • Neuro-Endocrine System: overlapping control involving both endocrine and nervous systems.
  • Endocrine cells are regulated by neural mechanisms.

Pituitary Gland

  • Also known as Hypophysis Cerebri
  • Pea-shaped endocrine gland connected to the hypothalamus.
  • Composed of anterior and posterior lobes.
  • Master control gland for hormone production in other endocrine glands.
  • 0.5-1.5g in weight

Pituitary Gland - Anterior Lobe (Adenohypophysis)

  • Composed of different cell types: acidophils (somatotropes and mammotropes), basophils (thyrotropes, corticotropes, gonadotropes) and chromophobes (reserve cells)
  • Secretes hormones regulating diverse bodily functions.

Hormones Secreted by Pars Distalis

  • STH/GH- Growth hormone, affects body growth.
  • Prolactin- Stimulates milk production
  • ACTH- Adrenocorticotropic hormone, targets the suprarenal glands.
  • FSH/LH- Follicle-stimulating and luteinizing hormones, involved in reproduction.
  • TSH- Stimulates thyroid function.

Thyroid Gland

  • Located in the neck, composed of follicles.
  • Thyroid hormones (T3, T4) increase metabolic rate.
  • Thyroid hormones are involved in growth and development
  • Contains follicular epithelial cells secreting hormones into the follicle lumen.

Parathyroid Glands

  • Small glands embedded on the posterior surface of the thyroid.
  • Chief cells are the most abundant cells secreting Parathyroid hormone (PTH) involved in calcium homeostasis, regulating blood calcium levels
  • Oxyphil cells: uncertain function, but present in larger quantities in older individuals.

Adrenal Glands

  • Located superior to the kidneys. Composed of adrenal cortex and adrenal medulla.
  • Adrenal cortex: secretes steroid hormones (mineralocorticoids, glucocorticoids, androgens).
  • Adrenal medulla: secretes catecholamines (epinephrine, norepinephrine).

Pineal Gland

  • Small gland in the brain
  • Secretes melatonin regulating circadian rhythms and influencing reproductive function.
  • Contains pinealocytes and glial cells.

Pancreatic Islets

  • Scattered in the exocrine tissue of the pancreas.
  • Alpha cells secrete glucagon.
  • Beta cells secrete insulin
  • Delta cells secrete somatostatin.

Other Endocrine Glands

  • Includes other glands with endocrine functions like testes, ovaries, gastrointestinal tract, and kidneys.

Female Reproductive System

  • Ovarian cycle: series of changes in the ovaries affecting follicle and oocyte development as well as hormonal variations.
  • Primordial follicle: contains a primary oocyte and a single layer of flattened follicle cells.
  • Primary follicle: contains a primary oocyte inside a cuboidal epithelium.
  • Secondary follicle: Contains a primary oocyte in a stratified follicle cells.
  • Mature-graafian follicle: Contains secondary oocyte.
  • Ovulation: the release of an ovum
  • Corpus luteum: structure formed during ovulation to produce hormones like estrogen and progesterone.
  • Corpus albicans: scar tissue formed after the corpus luteum degenerates.

Male Reproductive System

  • Spermatogenesis: process of sperm formation, starts at puberty.
  • Seminiferous tubules: where sperm development takes place surrounded by Sertoli cells which provide support and nutrition.
  • Interstitial cells of Leydig: secrete testosterone crucial for male characteristics.
  • Accessory glands; include seminal vesicles, prostate, and bulbourethral glands, they produce fluids nourishing and transporting sperm.

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Test your knowledge on the structure and function of the endocrine system with this quiz. Explore topics like the pituitary gland, hormone production, and cell types within the endocrine components. Ideal for students studying human anatomy and physiology.

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