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Questions and Answers
What is one of the rapid actions of insulin according to the text?
What is one of the rapid actions of insulin according to the text?
- Inhibition of protein degradation
- Activation of glycolytic enzymes (correct)
- Increase in mRNAs for lipogenic enzymes
- Stimulation of protein synthesis
Which tissue shows an increase in glucose entry, fatty acid synthesis, and triglyceride deposition due to insulin?
Which tissue shows an increase in glucose entry, fatty acid synthesis, and triglyceride deposition due to insulin?
- Skeletal muscle
- Adipose tissue (correct)
- Liver
- Cardiac muscle
What effect does insulin have on glycogen synthesis in muscle?
What effect does insulin have on glycogen synthesis in muscle?
- No effect on glycogen synthesis
- Decrease glycogen synthesis
- Increase glycogen synthesis (correct)
- Promote breakdown of glycogen
Which enzyme is inhibited by insulin according to the text?
Which enzyme is inhibited by insulin according to the text?
What is the effect of insulin on protein catabolism in muscle?
What is the effect of insulin on protein catabolism in muscle?
Which process does insulin activate in adipose tissue?
Which process does insulin activate in adipose tissue?
What is a common symptom of diabetes?
What is a common symptom of diabetes?
Which of the following happens in diabetes due to reduced entry of glucose into peripheral tissues?
Which of the following happens in diabetes due to reduced entry of glucose into peripheral tissues?
What is a potential complication of long-standing diabetes involving retinal scarring?
What is a potential complication of long-standing diabetes involving retinal scarring?
Which of the following is a microvascular complication of diabetes?
Which of the following is a microvascular complication of diabetes?
What contributes to the macrovascular abnormalities in diabetes?
What contributes to the macrovascular abnormalities in diabetes?
What type of abnormalities does diabetic neuropathy involve?
What type of abnormalities does diabetic neuropathy involve?
Which substance inhibits the secretion of insulin in the pancreas?
Which substance inhibits the secretion of insulin in the pancreas?
What can cause selective destruction of the B cells of the pancreatic islets?
What can cause selective destruction of the B cells of the pancreatic islets?
What effect does SS 28 have on insulin secretion?
What effect does SS 28 have on insulin secretion?
Which of the following is a stimulator of insulin secretion?
Which of the following is a stimulator of insulin secretion?
What is a symptom that can result from hyperglycemia?
What is a symptom that can result from hyperglycemia?
What hormone is found in the D cells of pancreatic islets and inhibits the secretion of insulin?
What hormone is found in the D cells of pancreatic islets and inhibits the secretion of insulin?
What is measured clinically as an integrated index of diabetic control?
What is measured clinically as an integrated index of diabetic control?
Which of the following substances increases the secretion of somatostatin in the pancreas?
Which of the following substances increases the secretion of somatostatin in the pancreas?
In diabetes, what happens to the rate at which amino acids are catabolized?
In diabetes, what happens to the rate at which amino acids are catabolized?
What leads to polydipsia in cases of hyperglycemia?
What leads to polydipsia in cases of hyperglycemia?
What role does SS 14 play in the pancreas?
What role does SS 14 play in the pancreas?
Why is there glycosuria in cases of hyperglycemia?
Why is there glycosuria in cases of hyperglycemia?
What is the primary cause of clinical diabetes according to the text?
What is the primary cause of clinical diabetes according to the text?
What distinguishes type 1 diabetes mellitus from type 2 diabetes mellitus?
What distinguishes type 1 diabetes mellitus from type 2 diabetes mellitus?
Which ancient term was used to describe conditions with a large urine volume, one type being sweet-tasting urine?
Which ancient term was used to describe conditions with a large urine volume, one type being sweet-tasting urine?
What type of diabetes is characterized by dysregulation of insulin release and insulin resistance in peripheral tissues?
What type of diabetes is characterized by dysregulation of insulin release and insulin resistance in peripheral tissues?
Which type of diabetes usually presents in children?
Which type of diabetes usually presents in children?
What is the defining characteristic of 'diabetes mellitus' according to the text?
What is the defining characteristic of 'diabetes mellitus' according to the text?
What is the primary function of insulin in regulating metabolism?
What is the primary function of insulin in regulating metabolism?
Which of the following is a hormone secreted by the pancreas that regulates ion transport in the intestine?
Which of the following is a hormone secreted by the pancreas that regulates ion transport in the intestine?
Which type of cells in the islets of Langerhans are also known as δ cells?
Which type of cells in the islets of Langerhans are also known as δ cells?
What is the role of somatostatin in islet cell secretion regulation?
What is the role of somatostatin in islet cell secretion regulation?
Which hormone plays a crucial role in regulating the intermediary metabolism of carbohydrates, proteins, and fats?
Which hormone plays a crucial role in regulating the intermediary metabolism of carbohydrates, proteins, and fats?
What is the function of glucagon in the regulation of metabolism?
What is the function of glucagon in the regulation of metabolism?
What is the effect of insulin on ketogenesis in the liver?
What is the effect of insulin on ketogenesis in the liver?
Which of the following is NOT an effect of insulin on muscle tissue?
Which of the following is NOT an effect of insulin on muscle tissue?
What is the primary effect of insulin on glucose transporters in cells?
What is the primary effect of insulin on glucose transporters in cells?
What does insulin do to the release of gluconeogenic amino acids in muscle tissue?
What does insulin do to the release of gluconeogenic amino acids in muscle tissue?
In which tissue does insulin play a role in the activation of lipoprotein lipase?
In which tissue does insulin play a role in the activation of lipoprotein lipase?
What effect does insulin have on fatty acid synthesis in the liver?
What effect does insulin have on fatty acid synthesis in the liver?
What is the term used to describe the situation in diabetes where there is extracellular glucose excess and intracellular glucose deficiency?
What is the term used to describe the situation in diabetes where there is extracellular glucose excess and intracellular glucose deficiency?
Microvascular abnormalities in diabetes include proliferative scarring of the retina leading to blindness. What is this condition called?
Microvascular abnormalities in diabetes include proliferative scarring of the retina leading to blindness. What is this condition called?
What is the primary cause of macrovascular abnormalities in diabetes?
What is the primary cause of macrovascular abnormalities in diabetes?
In diabetic nephropathy, what complication can result from the renal disease associated with diabetes?
In diabetic nephropathy, what complication can result from the renal disease associated with diabetes?
What type of nerves are involved in diabetic neuropathy?
What type of nerves are involved in diabetic neuropathy?
What is the term for the situation in diabetes where weight loss occurs despite increased appetite?
What is the term for the situation in diabetes where weight loss occurs despite increased appetite?
Which of the following factors is known to inhibit the secretion of insulin in the pancreas?
Which of the following factors is known to inhibit the secretion of insulin in the pancreas?
What is the effect of α-Adrenergic stimulators on insulin secretion?
What is the effect of α-Adrenergic stimulators on insulin secretion?
Which substance increases somatostatin secretion in the pancreas?
Which substance increases somatostatin secretion in the pancreas?
How does SS 28 differ from SS 14 in terms of inhibiting insulin secretion?
How does SS 28 differ from SS 14 in terms of inhibiting insulin secretion?
Which factor stimulates insulin secretion and inhibits glucagon secretion?
Which factor stimulates insulin secretion and inhibits glucagon secretion?
What is the primary role of somatostatin in pancreatic islets?
What is the primary role of somatostatin in pancreatic islets?
What is the fundamental defect in type 2 diabetes that most abnormalities can be traced back to?
What is the fundamental defect in type 2 diabetes that most abnormalities can be traced back to?
Which characteristic is not typically observed in a patient with diabetes?
Which characteristic is not typically observed in a patient with diabetes?
What is the primary therapeutic approach in managing type 1 diabetes?
What is the primary therapeutic approach in managing type 1 diabetes?
What is the main focus of lifestyle changes in early type 2 diabetes according to the text?
What is the main focus of lifestyle changes in early type 2 diabetes according to the text?
Which action characterizes insulin-sensitizing drugs in type 2 diabetes management?
Which action characterizes insulin-sensitizing drugs in type 2 diabetes management?
What paradoxical situation is described as 'starvation in the midst of plenty' in the context of type 2 diabetes?
What paradoxical situation is described as 'starvation in the midst of plenty' in the context of type 2 diabetes?
What is the term used to describe the situation in diabetes where there is extracellular glucose excess and intracellular glucose deficiency?
What is the term used to describe the situation in diabetes where there is extracellular glucose excess and intracellular glucose deficiency?
Which complication of diabetes involves proliferative scarring of the retina leading to blindness?
Which complication of diabetes involves proliferative scarring of the retina leading to blindness?
What leads to weight loss in diabetes despite an increased appetite?
What leads to weight loss in diabetes despite an increased appetite?
Which type of disease is diabetic nephropathy?
Which type of disease is diabetic nephropathy?
What is the main cause of macrovascular abnormalities in diabetes according to the text?
What is the main cause of macrovascular abnormalities in diabetes according to the text?
Which condition results from renal disease associated with diabetes?
Which condition results from renal disease associated with diabetes?
'Starvation in the midst of plenty' is primarily caused by what underlying defect in diabetes?
'Starvation in the midst of plenty' is primarily caused by what underlying defect in diabetes?
What is the result of accelerated atherosclerosis in diabetes?
What is the result of accelerated atherosclerosis in diabetes?