Endocrine Neoplasms 1 Overview

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson
Download our mobile app to listen on the go
Get App

Questions and Answers

Which symptom is NOT commonly associated with Medullary thyroid carcinoma in patients with MEN Type 2A?

  • Diarrhea
  • Episodic sweating
  • Hypertension
  • Memory problems (correct)

What is a common clinical manifestation of hypercalcemia due to Hyperparathyroidism in MEN Type 2A patients?

  • Nephrolithiasis
  • Constipation (correct)
  • Depression
  • Polyuria

Which of the following is a characteristic presentation of cutaneous lichen amyloidosis in multiple endocrine neoplasia type 2A?

  • Multiple pruritic, hyperpigmented, lichenoid papules in the neck
  • Multiple pruritic, hyperpigmented, lichenoid papules in the scapular area of the back (correct)
  • Multiple pruritic, hyperpigmented, lichenoid papules in the limbs
  • Multiple pruritic, hyperpigmented, lichenoid papules in the abdomen

What is a characteristic feature of neuromas in patients with MEN Type 2B?

<p>Bumps around the lips, tongue, and mouth (C)</p> Signup and view all the answers

How is screening for pheochromocytoma typically conducted in patients suspected of having multiple endocrine neoplasia type 2?

<p>24-hour urine test for elevated catecholamines and catecholamine metabolites (A)</p> Signup and view all the answers

In multiple endocrine neoplasia type 2, what does an abdominal MRI scan help to confirm?

<p>Medullary thyroid carcinoma confirmation (B)</p> Signup and view all the answers

What gene mutation is responsible for type 1 Multiple Endocrine Neoplasia?

<p>MENIN (C)</p> Signup and view all the answers

Which protein, produced by the MENIN gene, acts as a tumor suppressor?

<p>Menin (B)</p> Signup and view all the answers

What is the most common initial clinical manifestation of type 1 Multiple Endocrine Neoplasia?

<p>Hyperparathyroidism (C)</p> Signup and view all the answers

Which gene mutation is responsible for type 2 Multiple Endocrine Neoplasia?

<p>RET (A)</p> Signup and view all the answers

What is the location of the RET gene, responsible for type 2 Multiple Endocrine Neoplasia?

<p>Chromosome 10q11.2 (C)</p> Signup and view all the answers

What kind of cells does RET lead to hyperplasia in, in type 2 Multiple Endocrine Neoplasia?

<p>Target cells (B)</p> Signup and view all the answers

What is the peak incidence age range for non-endocrine malignant tumors of the pancreas?

<p>50-60 years old (D)</p> Signup and view all the answers

Which of the following symptoms is NOT typically associated with malignant pancreatic tumors?

<p>Chest pain (B)</p> Signup and view all the answers

Where do 2/3 of ductal adenocarcinomas of the pancreas tend to be located?

<p>Head of the pancreas (C)</p> Signup and view all the answers

Which of the following is a hormone-secreting non-endocrine neoplasm of the pancreas?

<p>Insulinoma (C)</p> Signup and view all the answers

What is a common diagnostic tool used to confirm obstructive jaundice in patients with pancreatic tumors?

<p>Liver function tests (C)</p> Signup and view all the answers

What is a potential consequence of late-stage diagnosis in over 90% of pancreatic cancer patients?

<p>No chance of cure (B)</p> Signup and view all the answers

Flashcards are hidden until you start studying

More Like This

Use Quizgecko on...
Browser
Browser