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Endo Test 3: Pharmacology - Diabetes

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Questions and Answers

What is the first-line treatment usually recommended for newly diagnosed Type 2 Diabetes Mellitus (T2DM)?

Oral drugs

Lifestyle modifications (correct)

Insulin therapy

Weight management

Which of the following is a potential adverse effect of insulin therapy in Type 1 diabetes?

Hyperglycemia

Weight loss

Improved lipid profile

Hypoglycemia (correct)

What is the primary role of metformin in decreasing blood glucose levels?

Enhancing glycogen breakdown

Limiting gluconeogenesis (correct)

Stimulating glucagon release

Increasing insulin production

Which of the following is NOT a common adverse effect of Metformin?

Migraine headache Signup and view all the answers

What is the primary mechanism of action of Sulfonylureas in the treatment of diabetes?

Binding to sulfonylurea receptor on pancreatic beta-cells Signup and view all the answers

How does Metformin improve insulin sensitivity?

By activating AMPK and increasing peripheral glucose uptake Signup and view all the answers

Which class of drugs inhibits the activity of KATP channels?

Sulfonylureas Signup and view all the answers

What is a common adverse effect associated with sulfonylureas?

Hypoglycemia Signup and view all the answers

Which of the following is NOT a characteristic of meglitinides?

They are largely protein-bound Signup and view all the answers

What is a significant adverse effect that a significant number of patients using sulfonylureas may experience?

Secondary failure Signup and view all the answers