Podcast
Questions and Answers
What is the benefit of taking medication with a meal?
What is the benefit of taking medication with a meal?
- It minimizes discomfort (correct)
- It increases the risk of hypoglycemia
- It stimulates insulin secretion
- It slows carbohydrate absorption
What is the mechanism of action of sulfonylureas?
What is the mechanism of action of sulfonylureas?
- They slow carbohydrate absorption in the small intestine
- They increase insulin resistance
- They stimulate the pancreas to secrete insulin (correct)
- They reduce insulin secretion
Why must patients taking sulfonylureas be counseled about hypoglycemia?
Why must patients taking sulfonylureas be counseled about hypoglycemia?
- Because they can cause kidney disease
- Because they can cause flatulence
- Because they can cause liver disease
- Because they can cause hypoglycemia (correct)
In which patients are sulfonylureas contraindicated?
In which patients are sulfonylureas contraindicated?
What is the mechanism of action of α-glucosidase inhibitors?
What is the mechanism of action of α-glucosidase inhibitors?
What side effect is commonly associated with α-glucosidase inhibitors?
What side effect is commonly associated with α-glucosidase inhibitors?
What is the primary site of insulin resistance in type 2 diabetes?
What is the primary site of insulin resistance in type 2 diabetes?
What is the initial response of the body to insulin resistance?
What is the initial response of the body to insulin resistance?
What is the effect of metformin on hepatic glucose production?
What is the effect of metformin on hepatic glucose production?
What is the benefit of metformin therapy in terms of insulin levels?
What is the benefit of metformin therapy in terms of insulin levels?
What is a common adverse effect of metformin therapy?
What is a common adverse effect of metformin therapy?
Why do patients treated with metformin monotherapy face little risk of hypoglycemia?
Why do patients treated with metformin monotherapy face little risk of hypoglycemia?
What is the primary effect of α-glucosidase inhibitors on carbohydrate absorption?
What is the primary effect of α-glucosidase inhibitors on carbohydrate absorption?
What is the primary reason why patients taking α-glucosidase inhibitors require treatment with glucose during hypoglycemia?
What is the primary reason why patients taking α-glucosidase inhibitors require treatment with glucose during hypoglycemia?
What is the function of incretins in the body?
What is the function of incretins in the body?
What is the effect of DPP-4 inhibitors on weight loss?
What is the effect of DPP-4 inhibitors on weight loss?
What is the primary role of DPP-4 in the body?
What is the primary role of DPP-4 in the body?
What is a potential side effect of DPP-4 inhibitors?
What is a potential side effect of DPP-4 inhibitors?
Which medication is an example of a DPP-4 inhibitor?
Which medication is an example of a DPP-4 inhibitor?
What is the effect of incretins on glucagon production?
What is the effect of incretins on glucagon production?
What is the primary consequence of insulin resistance in type 2 diabetes?
What is the primary consequence of insulin resistance in type 2 diabetes?
What is the effect of metformin on pancreatic β-cells?
What is the effect of metformin on pancreatic β-cells?
Why do patients with type 2 diabetes experience hunger despite high blood glucose levels?
Why do patients with type 2 diabetes experience hunger despite high blood glucose levels?
What is the primary mechanism of action of biguanides like metformin?
What is the primary mechanism of action of biguanides like metformin?
What is a common side effect of metformin therapy?
What is a common side effect of metformin therapy?
What is the primary reason why metformin is effective in normalizing blood glucose levels?
What is the primary reason why metformin is effective in normalizing blood glucose levels?
What is the primary effect of sulfonylureas on the pancreas?
What is the primary effect of sulfonylureas on the pancreas?
What is a common adverse effect of sulfonylureas?
What is a common adverse effect of sulfonylureas?
What is the primary site of action of α-glucosidase inhibitors?
What is the primary site of action of α-glucosidase inhibitors?
Why are sulfonylureas contraindicated in patients with advanced kidney or liver disease?
Why are sulfonylureas contraindicated in patients with advanced kidney or liver disease?
What is the onset of action of sulfonylureas?
What is the onset of action of sulfonylureas?
What should patients taking sulfonylureas be counseled about?
What should patients taking sulfonylureas be counseled about?
What is the reason why foods containing complex carbohydrates are ineffective in treating hypoglycemia in patients taking α-glucosidase inhibitors?
What is the reason why foods containing complex carbohydrates are ineffective in treating hypoglycemia in patients taking α-glucosidase inhibitors?
What is the primary action of incretins on insulin and glucagon production?
What is the primary action of incretins on insulin and glucagon production?
What is the consequence of DPP-4 inhibitors on gastrointestinal hormones?
What is the consequence of DPP-4 inhibitors on gastrointestinal hormones?
What is the effect of α-glucosidase inhibitors on the body's carbohydrate absorption?
What is the effect of α-glucosidase inhibitors on the body's carbohydrate absorption?
Why are DPP-4 inhibitors associated with higher rates of pancreatitis?
Why are DPP-4 inhibitors associated with higher rates of pancreatitis?
What is the primary effect of incretins on digestion?
What is the primary effect of incretins on digestion?
What is the effect of DPP-4 inhibitors on appetite?
What is the effect of DPP-4 inhibitors on appetite?
What is the treatment required for patients who develop hypoglycemia while taking α-glucosidase inhibitors?
What is the treatment required for patients who develop hypoglycemia while taking α-glucosidase inhibitors?
What is the primary site of insulin resistance in type 2 diabetes?
What is the primary site of insulin resistance in type 2 diabetes?
What is the effect of metformin on the body's fuel supply?
What is the effect of metformin on the body's fuel supply?
What is the role of metformin in improving insulin sensitivity?
What is the role of metformin in improving insulin sensitivity?
Why do patients with type 2 diabetes experience hunger despite high blood glucose levels?
Why do patients with type 2 diabetes experience hunger despite high blood glucose levels?
What is the primary mechanism by which metformin reduces hepatic glucose production?
What is the primary mechanism by which metformin reduces hepatic glucose production?
What is the benefit of metformin therapy in terms of hypoglycemia risk?
What is the benefit of metformin therapy in terms of hypoglycemia risk?
What is the primary mechanism of action of sulfonylureas in the body?
What is the primary mechanism of action of sulfonylureas in the body?
What is a common side effect of α-glucosidase inhibitors?
What is a common side effect of α-glucosidase inhibitors?
Why should patients taking sulfonylureas be cautious when skipping or delaying meals?
Why should patients taking sulfonylureas be cautious when skipping or delaying meals?
What is the benefit of sulfonylureas in terms of their onset of action?
What is the benefit of sulfonylureas in terms of their onset of action?
In which patients are sulfonylureas contraindicated?
In which patients are sulfonylureas contraindicated?
What is the primary effect of α-glucosidase inhibitors on the body's glucose levels?
What is the primary effect of α-glucosidase inhibitors on the body's glucose levels?
What is the primary action of α-glucosidase inhibitors?
What is the primary action of α-glucosidase inhibitors?
What is the mechanism of action of DPP-4 inhibitors?
What is the mechanism of action of DPP-4 inhibitors?
Why are DPP-4 inhibitors linked with weight loss?
Why are DPP-4 inhibitors linked with weight loss?
What is the treatment required for patients who develop hypoglycemia while taking α-glucosidase inhibitors?
What is the treatment required for patients who develop hypoglycemia while taking α-glucosidase inhibitors?
What is the primary role of incretins in the body?
What is the primary role of incretins in the body?
What is the consequence of DPP-4 enzyme activity?
What is the consequence of DPP-4 enzyme activity?
What is the effect of α-glucosidase inhibitors on blood glucose levels?
What is the effect of α-glucosidase inhibitors on blood glucose levels?
What is the potential side effect of DPP-4 inhibitors?
What is the potential side effect of DPP-4 inhibitors?
What is the primary response of the body to insulin resistance in type 2 diabetes?
What is the primary response of the body to insulin resistance in type 2 diabetes?
What is the primary mechanism by which metformin acts to improve insulin action?
What is the primary mechanism by which metformin acts to improve insulin action?
Why do patients with type 2 diabetes experience hunger despite high blood glucose levels?
Why do patients with type 2 diabetes experience hunger despite high blood glucose levels?
What is a common adverse effect of metformin therapy?
What is a common adverse effect of metformin therapy?
What is the primary consequence of insulin resistance in type 2 diabetes?
What is the primary consequence of insulin resistance in type 2 diabetes?
What is the effect of metformin on pancreatic β-cells?
What is the effect of metformin on pancreatic β-cells?
What is the primary benefit of taking sulfonylureas in patients with type 2 diabetes?
What is the primary benefit of taking sulfonylureas in patients with type 2 diabetes?
What is the primary reason why patients taking sulfonylureas should be cautious when skipping or delaying meals?
What is the primary reason why patients taking sulfonylureas should be cautious when skipping or delaying meals?
What is the primary effect of α-glucosidase inhibitors on the body?
What is the primary effect of α-glucosidase inhibitors on the body?
Why are sulfonylureas contraindicated in patients with advanced kidney or liver disease?
Why are sulfonylureas contraindicated in patients with advanced kidney or liver disease?
What is a common side effect of taking α-glucosidase inhibitors?
What is a common side effect of taking α-glucosidase inhibitors?
What is the primary benefit of sulfonylureas in terms of their onset of action?
What is the primary benefit of sulfonylureas in terms of their onset of action?
What is the effect of α-glucosidase inhibitors on carbohydrate absorption?
What is the effect of α-glucosidase inhibitors on carbohydrate absorption?
What is the primary role of DPP-4 in the body?
What is the primary role of DPP-4 in the body?
What is the effect of DPP-4 inhibitors on insulin and glucagon production?
What is the effect of DPP-4 inhibitors on insulin and glucagon production?
Why are DPP-4 inhibitors linked with weight loss?
Why are DPP-4 inhibitors linked with weight loss?
What is the primary effect of α-glucosidase inhibitors on blood glucose levels?
What is the primary effect of α-glucosidase inhibitors on blood glucose levels?
What is the reason why foods containing complex carbohydrates are ineffective in treating hypoglycemia in patients taking α-glucosidase inhibitors?
What is the reason why foods containing complex carbohydrates are ineffective in treating hypoglycemia in patients taking α-glucosidase inhibitors?
What is the effect of incretins on digestion?
What is the effect of incretins on digestion?
What is a common side effect of DPP-4 inhibitors?
What is a common side effect of DPP-4 inhibitors?
Flashcards
Medication with a meal
Medication with a meal
It minimizes discomfort from the medication.
Sulfonylureas mechanism
Sulfonylureas mechanism
They stimulate the pancreas to secrete insulin.
Hypoglycemia counseling for sulfonylureas
Hypoglycemia counseling for sulfonylureas
Patients are at risk of low blood sugar levels.
Sulfonylureas contraindications
Sulfonylureas contraindications
Signup and view all the flashcards
α-glucosidase inhibitors action
α-glucosidase inhibitors action
Signup and view all the flashcards
Common side effect of α-glucosidase inhibitors
Common side effect of α-glucosidase inhibitors
Signup and view all the flashcards
Insulin resistance in type 2 diabetes
Insulin resistance in type 2 diabetes
Signup and view all the flashcards
Body's response to insulin resistance
Body's response to insulin resistance
Signup and view all the flashcards
Metformin effect on hepatic glucose production
Metformin effect on hepatic glucose production
Signup and view all the flashcards
Metformin and insulin levels
Metformin and insulin levels
Signup and view all the flashcards
Adverse effect of metformin
Adverse effect of metformin
Signup and view all the flashcards
Low hypoglycemia risk with metformin
Low hypoglycemia risk with metformin
Signup and view all the flashcards
Primary effect of α-glucosidase inhibitors
Primary effect of α-glucosidase inhibitors
Signup and view all the flashcards
Treating hypoglycemia with α-glucosidase inhibitors
Treating hypoglycemia with α-glucosidase inhibitors
Signup and view all the flashcards
Incretins function
Incretins function
Signup and view all the flashcards
DPP-4 inhibitors and weight loss
DPP-4 inhibitors and weight loss
Signup and view all the flashcards
Role of DPP-4 in the body
Role of DPP-4 in the body
Signup and view all the flashcards
Potential side effect of DPP-4 inhibitors
Potential side effect of DPP-4 inhibitors
Signup and view all the flashcards
Example of DPP-4 inhibitor
Example of DPP-4 inhibitor
Signup and view all the flashcards
Effect of incretins on glucagon
Effect of incretins on glucagon
Signup and view all the flashcards
Insulin resistance consequence
Insulin resistance consequence
Signup and view all the flashcards
Metformin and pancreatic β-cells
Metformin and pancreatic β-cells
Signup and view all the flashcards
Hunger in type 2 diabetes despite high blood glucose
Hunger in type 2 diabetes despite high blood glucose
Signup and view all the flashcards
Biguanides like metformin action
Biguanides like metformin action
Signup and view all the flashcards
Metformin and hypoglycemia risk
Metformin and hypoglycemia risk
Signup and view all the flashcards
Sulfonylureas action on pancreas
Sulfonylureas action on pancreas
Signup and view all the flashcards
Adverse effect of sulfonylureas
Adverse effect of sulfonylureas
Signup and view all the flashcards
α-glucosidase inhibitors action site
α-glucosidase inhibitors action site
Signup and view all the flashcards
Sulfonylureas in kidney or liver disease
Sulfonylureas in kidney or liver disease
Signup and view all the flashcards
Onset of sulfonylureas
Onset of sulfonylureas
Signup and view all the flashcards
Counseling for sulfonylureas
Counseling for sulfonylureas
Signup and view all the flashcards
Complex carbohydrates in hypoglycemia
Complex carbohydrates in hypoglycemia
Signup and view all the flashcards
Incretins effect on insulin and glucagon
Incretins effect on insulin and glucagon
Signup and view all the flashcards
DPP-4 inhibitors and gastrointestinal hormones
DPP-4 inhibitors and gastrointestinal hormones
Signup and view all the flashcards
Effect of α-glucosidase inhibitors on absorption
Effect of α-glucosidase inhibitors on absorption
Signup and view all the flashcards
DPP-4 inhibitors and pancreatitis
DPP-4 inhibitors and pancreatitis
Signup and view all the flashcards
Incretins effect on digestion
Incretins effect on digestion
Signup and view all the flashcards
DPP-4 inhibitors effect on appetite
DPP-4 inhibitors effect on appetite
Signup and view all the flashcards
Hypoglycemia treatment with α-glucosidase inhibitors
Hypoglycemia treatment with α-glucosidase inhibitors
Signup and view all the flashcards
