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Questions and Answers
The half-life of a drug is the time it takes for the concentration of drug in the body to decrease by ______.
half
Absorption is the process by which a drug enters the bloodstream after being ______.
administered
Distribution is the process by which a drug is transported from the site of absorption to its site of action within the ______.
body
Metabolism is one of the processes essential for determining the efficacy and safety of ______.
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Excretion is a process that involves eliminating drugs or their metabolites from the ______.
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The speed and extent of absorption can be influenced by factors such as the formulation of the drug, the presence of ______, and the rate of blood flow to the absorption site.
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Study Notes
EMT Pharmacokinetics
Pharmacokinetics is a discipline of science concerned with understanding the time course of drug concentration within the body. This includes drug absorption, distribution, metabolism, and excretion. These processes are essential for determining the efficacy and safety of drugs. In the case of emergency medical technicians (EMTs), understanding pharmacokinetics is crucial for administering medications effectively and safely.
Half-Life
The half-life of a drug is the time it takes for the concentration of drug in the body to decrease by half. It is a measure of the persistence of a drug within the body. The half-life of a drug can be affected by various factors such as the route of administration, age, liver and kidney function, and drug interactions.
Absorption
Absorption is the process by which a drug enters the bloodstream after being administered. Absorption can occur through various routes, including oral, intravenous, intramuscular, and subcutaneous. The speed and extent of absorption can be influenced by factors such as the formulation of the drug, the presence of food, and the rate of blood flow to the absorption site.
Distribution
Distribution is the process by which a drug is transported from the site of absorption to its site of action within the body. The distribution of a drug is influenced by factors such as blood flow, the lipid and water solubility of the drug, and the presence of proteins that can bind to the drug.
Metabolism
Metabolism is the process by which a drug is chemically modified within the body. The liver is the primary organ responsible for drug metabolism, and it can break down drugs through various mechanisms, including oxidation, reduction, and hydrolysis. The rate and extent of metabolism can be influenced by factors such as liver function and the presence of co-administered drugs.
Excretion
Excretion is the process by which a drug is eliminated from the body. The primary route of drug excretion is through the kidneys into the urine. Excretion can also occur through the lungs, skin, feces, and bile. The rate and extent of excretion are influenced by factors such as renal function, the lipid solubility of the drug, and the presence of co-administered drugs.
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Description
Learn about pharmacokinetics, which involves drug absorption, distribution, metabolism, and excretion in the body. Explore concepts such as half-life, absorption routes, distribution mechanisms, metabolism processes, and drug excretion. Essential knowledge for effective medication administration by emergency medical technicians (EMTs).
