Acid-Base Disorders Practice
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In a patient experiencing a mixed acid-base disorder, what finding would suggest the presence of the condition, even if the pH is within the normal range?

  • Compensatory mechanisms have fully corrected the pH.
  • Absence of any renal or respiratory compensation.
  • Normal PaCO2 and bicarbonate levels.
  • Alterations in both PaCO2 and bicarbonate levels. (correct)

How does the body maintain acid-base balance when excess carbon dioxide ($CO_2$) is present in the blood?

  • By decreasing the production of bicarbonate ($HCO_3^-$).
  • By converting $CO_2$ into a strong base.
  • By forming carbonic acid ($H_2CO_3$), which dissociates into $H^+$ and $HCO_3^-$. (correct)
  • By directly increasing the pH of the blood.

What is the primary role of arterial blood gas (ABG) analysis in assessing a patient's condition?

  • To assess the patient's glucose metabolism exclusively.
  • To measure the patient's hydration status only.
  • To provide information about the body's ability to regulate pH, acid-base status, underlying cause of imbalance, and overall oxygen status. (correct)
  • To determine the patient's electrolyte levels exclusively.

In a patient with a pH of 7.2, which of the following conditions is most likely present?

<p>Acidosis. (B)</p> Signup and view all the answers

Which statement accurately describes the role of hydrogen ions ($H^+$) in determining pH?

<p>Increased $H^+$ concentration results in decreased pH. (D)</p> Signup and view all the answers

A patient's arterial blood gas (ABG) results show a pH of 7.50. Which condition does this indicate?

<p>Alkalosis (A)</p> Signup and view all the answers

What is the fundamental difference between an acid and a base in terms of hydrogen ions ($H^+$)?

<p>Acids produce $H^+$, while bases accept $H^+$. (B)</p> Signup and view all the answers

Why is maintaining acid-base balance crucial for overall health?

<p>It is essential for all cellular metabolism and homeostasis. (C)</p> Signup and view all the answers

A patient with chronic obstructive pulmonary disease (COPD) is at risk for developing respiratory acidosis. Which assessment finding would indicate the patient is experiencing respiratory acidosis?

<p>Decreased level of consciousness and shallow respirations (B)</p> Signup and view all the answers

A patient is admitted with respiratory acidosis. Which of the following interventions is the highest priority for the nurse?

<p>Maintaining a patent airway (D)</p> Signup and view all the answers

A patient is hyperventilating due to anxiety. Which of the following arterial blood gas (ABG) results would indicate respiratory alkalosis?

<p>pH 7.50, PaCO2 30 mm Hg (A)</p> Signup and view all the answers

A patient with respiratory alkalosis is experiencing lightheadedness and tingling in their fingers. What should the nurse instruct the patient to do?

<p>Breathe into a paper bag (D)</p> Signup and view all the answers

When monitoring a patient with respiratory acidosis, which electrolyte imbalance is the nurse most concerned about?

<p>Hyperkalemia (C)</p> Signup and view all the answers

A patient is diagnosed with respiratory alkalosis secondary to a panic attack. Besides breathing techniques, what other intervention might be considered with caution?

<p>Administering sedatives (C)</p> Signup and view all the answers

Why should oxygen be administered cautiously in a patient with respiratory acidosis?

<p>It may suppress the hypoxic drive in patients with chronic respiratory conditions. (A)</p> Signup and view all the answers

A patient presents with rapid, shallow respirations and altered mental status. An arterial blood gas (ABG) reveals a pH of 7.25 and a PaCO2 of 60 mm Hg. Which condition is most likely indicated by these results?

<p>Respiratory acidosis (B)</p> Signup and view all the answers

A patient is experiencing metabolic alkalosis. Which physiological response would the body initiate to compensate for this imbalance?

<p>Decreased respiratory rate to retain more CO2. (A)</p> Signup and view all the answers

A patient presents with the following arterial blood gas (ABG) values: pH = 7.48, HCO3 = 30 mEq/L, and PaCO2 = 48 mmHg. Which of the following conditions is most likely?

<p>Partially compensated metabolic alkalosis. (B)</p> Signup and view all the answers

Which of the following clinical manifestations would be most indicative of a patient experiencing metabolic alkalosis?

<p>Increased deep tendon reflexes and muscle spasms. (C)</p> Signup and view all the answers

A patient with prolonged vomiting is at risk for developing metabolic alkalosis. Which of the following mechanisms contributes to this acid-base imbalance?

<p>Loss of hydrochloric acid (HCl) from the stomach. (D)</p> Signup and view all the answers

A patient's arterial blood gas results show a normal pH, elevated PaCO2, and elevated HCO3. Which condition does this indicate?

<p>Compensated respiratory acidosis. (A)</p> Signup and view all the answers

A patient is diagnosed with metabolic alkalosis. Which of the following electrolyte imbalances is most likely to occur concurrently?

<p>Hypokalemia. (A)</p> Signup and view all the answers

According to the ROME mnemonic, how are the pH and CO2 related in respiratory conditions?

<p>They are opposite; an increase in one causes a decrease in the other. (C)</p> Signup and view all the answers

A patient undergoing nasogastric suctioning is at risk for developing metabolic alkalosis. What is the primary mechanism by which this occurs?

<p>Loss of gastric acid containing hydrochloric acid (HCl). (C)</p> Signup and view all the answers

A patient experiencing respiratory alkalosis reports tingling in their fingers and toes. Which underlying physiological process is most likely contributing to this symptom?

<p>Increased nerve excitability due to decreased calcium binding to albumin, leading to hypocalcemia. (B)</p> Signup and view all the answers

A patient is using pursed-lip breathing. What acid-base imbalance is the patient most likely experiencing and what is the intended effect of this breathing technique?

<p>Respiratory alkalosis; to control their breathing. (C)</p> Signup and view all the answers

A patient is instructed to breathe into a paper bag for 6-12 breaths. What acid-base imbalance is the patient most likely suffering from and what is the principle behind this intervention?

<p>Respiratory alkalosis; to increase CO2 reuptake. (B)</p> Signup and view all the answers

What is the primary physiological effect of a bicarbonate (HCO3-) deficit in the body?

<p>Decreased blood pH, leading to acidosis. (C)</p> Signup and view all the answers

In metabolic acidosis, the respiratory system attempts to compensate for the acid-base imbalance. What is the primary mechanism that the respiratory system employs to achieve this compensation?

<p>Increasing the rate and depth of respiration to eliminate CO2. (B)</p> Signup and view all the answers

What is a key characteristic of Kussmaul breathing, and under which acid-base imbalance condition is it typically observed?

<p>Deep, labored breaths; metabolic acidosis. (B)</p> Signup and view all the answers

A patient with metabolic acidosis is experiencing arrhythmias and hypotension. Which of the following interventions is most important to address these cardiovascular cues?

<p>Administering oxygen and addressing the underlying cause of the acidosis. (D)</p> Signup and view all the answers

In the management of a patient with lactic acidosis, why is the administration of oxygen a crucial intervention?

<p>To improve tissue oxygenation and reduce anaerobic metabolism. (D)</p> Signup and view all the answers

In partial compensation for an acid-base imbalance, what key indicator remains outside the normal range?

<p>Blood pH (D)</p> Signup and view all the answers

Which of the following mechanisms does the body employ to compensate for a metabolic disorder?

<p>Changes in ventilation rate managed by the lungs (C)</p> Signup and view all the answers

What characterizes complete compensation in an acid-base imbalance?

<p>Return of pH to the normal range (B)</p> Signup and view all the answers

In respiratory acidosis, what changes in arterial blood gases would you typically observe?

<p>Decreased pH and increased PaCO2 (C)</p> Signup and view all the answers

What is the direct consequence of hypoventilation on blood gas levels?

<p>Increased carbon dioxide levels (C)</p> Signup and view all the answers

If a patient has a condition causing respiratory depression, which acid-base imbalance is most likely to develop?

<p>Respiratory acidosis (C)</p> Signup and view all the answers

How do the kidneys typically respond to respiratory acidosis in terms of acid-base balance?

<p>Increasing absorption of HCO3- and increasing excretion of H+ (B)</p> Signup and view all the answers

Which of the following scenarios can directly lead to respiratory acidosis?

<p>Airway obstruction (A)</p> Signup and view all the answers

Flashcards

Acid

Produces hydrogen ions (H+) and lowers pH.

Base

Accepts hydrogen ions (H+) and raises pH.

Mixed Acid-Base Disorders

Two or more primary acid-base disorders occurring simultaneously.

Job of Acids and Bases

Maintains stable H+ concentration, neutral environment, and compensates for imbalances.

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Importance of Acid-Base Balance

Essential for homeostasis and cellular metabolism.

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Hydrogen Ions

Indicate acidity, indicated alkalinity.

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Acidosis

A condition of excessive acidity in body fluids, with pH below 7.35.

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Alkalosis

A condition of excessive alkalinity in body fluids, with pH above 7.45.

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Acid-Base Balance Regulation

Retaining/excreting H+ and HCO3- (kidneys); retaining/expelling CO2 (lungs) to balance pH.

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Compensation (Acid-Base)

When one system compensates for another to regain acid-base balance. (Lungs for metabolic; Kidneys for respiratory)

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Partial Compensation

pH remains abnormal; compensation is occurring but hasn't fully corrected the imbalance.

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Complete Compensation

pH returns to normal; the body has successfully corrected the acid-base imbalance.

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Acid-Base Disorders

Conditions where the body's pH deviates from the normal range.

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H+

Hydrogen ion. Influences the pH level in the body.

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Respiratory Acidosis

Decreased ventilation leading to increased PaCO2 and decreased pH.

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PaCO2

Partial pressure of carbon dioxide in arterial blood; increases in respiratory acidosis.

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Respiratory Alkalosis Cues

Periods of apnea and hyperventilation.

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Pursed-Lip Breathing

Method to control breathing in respiratory alkalosis.

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Paper Bag Breathing

Patient takes 6-12 natural breaths with a paper bag over the mouth & nose.

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Metabolic Acidosis

Gain of acid and/or inability to excrete acid.

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Respiratory Compensation (Metabolic Acidosis)

Elimination of CO2 to raise pH.

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Kussmaul Breathing

Deep, labored breathing associated with metabolic acidosis.

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Neurologic Metabolic Acidosis Cues

Dull headache, lethargy, confusion, coma.

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Cardiovascular cues of Metabolic Acidosis

Arrhythmias, hypotension.

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Metabolic Alkalosis

Loss of strong acid leading to bicarbonate excess.

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HCO3- Excess

An increase in bicarbonate levels contributing to metabolic alkalosis.

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pH Increase

An increase in pH levels caused by a decrease in hydrogen ions.

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Nasogastric Suction

A cause of metabolic alkalosis due to loss of gastric acid.

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Respiratory Cue

Slow, Shallow Breathing

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Neurologic cues

Irritability, disorientation, belligerence

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Acid-Base Pneumonic

Respiratory - Opposite, Metabolic - Equal

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Compensation

pH Tells the Tale

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Chronic Respiratory Problems

Long-term lung problems that can lead to retained CO2.

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Hyperventilation

Increased ventilation that lowers carbon dioxide levels in the blood.

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Respiratory Alkalosis

A condition where ventilation increases, leading to decreased PaCO2 and increased pH.

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Cues of Respiratory Acidosis

Rapid and shallow breathing, dizziness, disorientation, headache, coma.

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Actions for Respiratory Acidosis

Maintain airway, give O2 cautiously, monitor vitals/ABGs/K+, avoid over-sedation, teach patient.

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Actions for Respiratory Alkalosis

Slow breathing, monitor vitals/ABGs/K+, consider sedation, teach breathing techniques, paper bag.

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Take Actions for Respiratory Alkalosis

Instruct to breathe slowly & less deeply, monitor vital signs, ABG levels and administer sedatives cautiously.

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Study Notes

  • Acid produces H+ and lowers pH
  • Base accepts H+ and raises pH

Mixed Acid-Base Disorders

  • Two or more primary acid-base disorders occurring simultaneously
  • Common in hospitalized individuals
  • The degree of compensation is determined in these cases
  • Renal and respiratory compensation rarely normalizes pH
  • Alterations in PaCO2, bicarbonate levels, and normal pH can occur

Job of Acids and Bases

  • Maintains pH levels, stable H+ concentrations
  • Provides a neutral environment and compensates for imbalances

Importance of Balance

  • Necessary for homeostasis
  • Essential for cellular metabolism

Hydrogen Ions

  • Maintain homeostasis of H+ concentration in body fluids
  • H+ indicates acid, while “H+ indicates alkaline

pH and Hydrogen Ion Concentration

  • Hydrogen ion concentration is expressed as pH
  • H+ results in pH and “H+ results in 'pH

Acids, Bases and H2CO3

  • H2CO3 (carbonic acid) forms when CO2 dissolves in H2O
  • Dissociates to release H+ and HCO3-

Acidosis vs Alkalosis

  • Conditions related to acid-base status imbalance

Acidosis

  • Indicates excessive acidity in body fluids
  • pH is below 7.35

Alkalosis

  • Occurs when pH is above 7.45

Arterial Blood Gas Values (ABG)

  • Provide information about body's ability to regulate pH
  • Indicate a patient's acid-base status, the cause of imbalance, and overall oxygen status

Detection of Imbalances

  • Kidneys retain or excrete H+ and HCO3-
  • Lungs retain or expel CO2

Compensation

  • One system helps when the primary system cannot regain acid-base balance

Lung and Kidney Response

  • Lungs may respond to a metabolic disorder
  • Kidneys may respond to a respiratory disorder

Partial and Complete Compensation

  • Partial compensation occurs when pH remains abnormal
  • Complete compensation occurs when pH returns to normal

Acid-Base Disorders

  • Conditions occurring when body's pH varies from normal

Hydrogen Ion (H+)

  • Influences pH level in the body

Respiratory Acidosis

  • Decreased ventilation leads to increased PaCO2 and decreased pH

Hypoventilation

  • A decrease in ventilation results in increased carbon dioxide levels

PaCO2 (Partial Pressure of Carbon Dioxide)

  • Increases in arterial blood during respiratory acidosis

H2CO3

  • Carbonic acid that forms from the reaction of CO2 dissolved in H2O

Renal Compensation in Respiratory Acidosis

  • Kidneys increase absorption of HCO3- and excretion of H+

Respiratory Depression

  • A decrease in the rate and depth of breathing

Obstruction

  • Can lead to respiratory acidosis by preventing normal airflow

Chronic Respiratory Problems

  • Long-term conditions that may contribute to respiratory acidosis

Recognizing Respiratory Acidosis

  • Signs include: rapid and shallow respirations (shallow and depressed), dizziness, disorientation, headache, coma, arrhythmias, hypotension, seizures, and muscle twitching

Actions for Respiratory Acidosis

  • Maintain patent airway
  • Administer oxygen cautiously
  • Monitor vital signs (respiratory rate and depth) and ABG levels
  • Monitor serum potassium level
  • Administer sedatives cautiously
  • Reinforce patient teachings

Respiratory Alkalosis

  • Increased ventilation leads to decreased PaCO2 and increased pH

Hyperventilation

  • An increase in ventilation results in decreased carbon dioxide levels

Actions for Respiratory Alkalosis

  • Instruct patient to breathe slowly and less deeply
  • Monitor vital signs and ABG levels
  • Monitor serum potassium level
  • Administer sedatives cautiously
  • Reinforce patient teachings
  • Have the patient take 6-12 natural breaths with a paper bag over the mouth and nose, then remove the bag for easy natural breaths

Recognize Cues of Respiratory Alkalosis:

  • Periods of apnea and hyperventilation (respiratory)
  • Lightheadedness, confusion, lethargy (neurological)
  • Tachycardia and arrhythmias (cardiovascular)
  • Tingling of extremities, hyperreflexia, tetany, and seizures (neuromuscular)
  • Epigastric pain, nausea, and vomiting (gastrointestinal)

Pursed-Lip Breathing Techniques

  • Helps control breathing in respiratory alkalosis

Natural Breaths with Paper Bag

  • Taking 6-12 natural breaths with a paper bag over the mouth and nose

Metabolic Acidosis

  • Gain of acid and/or inability to excrete acid

HCO3- Deficit

  • A decrease in bicarbonate levels contributes to metabolic acidosis

pH Due to Excess H+

  • Decreases in pH levels are caused by an increase in hydrogen ions

Respiratory Compensation in Metabolic Acidosis

  • Body eliminates CO2 to raise pH
  • Ventilation efforts retain CO2

Kussmaul Breathing

  • Deep, labored breathing associated with metabolic acidosis, particularly DKA

Respiratory Cues of Metabolic Acidosis

  • Kussmaul breathing and fruity breath are associated with DKA (Diabetic Ketoacidosis)

Neurologic Cues of Metabolic Acidosis

  • Dull headache, lethargy, confusion, and coma can occur

Cardiovascular Cues of Metabolic Acidosis

  • Arrhythmias and hypotension can occur

Neuromuscular Cues of Metabolic Acidosis

  • Tingling and numbness in the extremities can occur

Gastrointestinal Cues of Metabolic Acidosis

  • Abdominal pain, anorexia, nausea, and vomiting can occur

Actions for Metabolic Acidosis

  • Monitor neurological status
  • Administer O2
  • Monitor ABG
  • Monitor K
  • Assess respiratory functions

Metabolic Alkalosis

  • Loss of strong acid leads to bicarbonate excess

HCO3- Excess

  • Increase in bicarbonate levels contributes to metabolic alkalosis

pH Due to Decrease in H+

  • Increase in pH levels is caused by a decrease in hydrogen ions

Nasogastric Suction

  • Can cause metabolic alkalosis due to loss of gastric acid

Respiratory Cues of Metabolic Alkalosis

  • Slow, shallow breathing can occur

Neurologic Cues of Metabolic Alkalosis

  • Irritability, disorientation, belligerence can occur

Cardiovascular Cues of Metabolic Alkalosis

  • Dysrhythmias can occur

Neuromuscular Cues of Metabolic Alkalosis

  • Tingling, muscle cramps, and tetany can occur

Gastrointestinal Cues of Metabolic Alkalosis

  • Anorexia, nausea, and vomiting can occur

Acid-Base Pneumonic (ROME)

  • Respiratory - Opposite, Metabolic - Equal

Compensation

  • pH changes indicate compensation mechanisms

Partially Compensated Respiratory Acidosis

  • Low pH (<7.35)
  • High PaCO2 (>45)
  • High HCO3 (>28)

Partially Compensated Metabolic Alkalosis

  • Elevated pH
  • High HCO3 (>28)
  • High PaCO2 (> 45)

Compensated Respiratory Acidosis

  • Normal pH
  • High CO2 (Acidic)
  • High HCO3(Alkalotic, >28)

Uncompensated Respiratory Acidosis

  • Acidic pH (<7.35)
  • High PaCO2 (>45)
  • Normal HCO3 (22-28)

Compensated Respiratory Alkalosis

  • Normal pH (7.35-7.45)
  • Low CO2 (<35 (alkalotic))
  • Low HCO3 (<22)

Uncompensated Respiratory Alkalosis

  • High pH (>7.45)
  • Low PaCO2 (<35)
  • Normal HCO3 (22-28)

Compensated Metabolic Acidosis

  • Normal pH (7.35-7.45)
  • Low PaCO2 (< 35)
  • Low HCO3 (< 22)

Uncompensated Metabolic Acidosis

  • Low pH (<7.35)
  • Normal PaCO2 (between 35-45)
  • Low HCO3 (<22)

Compensated Metabolic Alkalosis

  • Normal pH
  • High PaCO2 (> 45)
  • High HCO3 (> 28)

Uncompensated Metabolic Alkalosis

  • High pH (>7.45)
  • Normal PaCO2 (35-45)
  • High HCO3 (>28)

HCO3 Normal Range

  • Normal range is typically 22 - 28 mEq/L

Lung and Kidney Response

  • Lungs may respond to a metabolic disorder
  • Kidneys may respond to a respiratory disorder

Respiratory Acidosis Etiology

  • Respiratory depression, obstruction, or chronic respiratory problems

Respiratory Alkalosis Etiology

  • Any factor that contributes to hyperventilation

Renal Compensation for Respiratory Alkalosis

  • Involves absorption of H+ and excretion of HCO3- in urine

Metabolic Acidosis Etiology

  • DKA, renal failure, diarrhea, salicylate poisoning, and starvation

Respiratory Acidosis Compensation

  • Involves eliminating excess CO2

Respiratory Alkalosis Compensation

  • Body retains CO2

Metabolic Acidosis Compensation:

  • Conserving HCO3- and eliminating excess H+

Metabolic Alkalosis Compensation

  • Conserve H+, increase CO2 retention, and increase H⁺ production

Acid-Base Disorders Criteria

  • Uncompensated: pH and one other value is abnormal
  • Partially Compensated: All 3 values will be abnormal
  • Compensated: pH is normal while other two values are abnormal

Actions in Metabolic Acidosis

  • Monitor neurologic status, vital signs, and respiratory rate and depth
  • Position patient to facilitate breathing and administer O2 to correct lactic acidosis
  • Monitor ABG levels
  • Monitor HCO3- and K+ levels
  • Administer IV fluids containing as ordered
  • Administer insulin and NS to correct hyperglycemia
  • Administer NaHCO3 (SODIUM BICARB) cautiously
  • Institute cardiac monitoring for patients with K+
  • Reinforced patient teachings

Actions for Metabolic Alkalosis

  • Monitor vital signs and assess neurological status
  • Monitor ABG values
  • Administer IVF and electrolyte supplements as ordered and monitor patients at risk
  • Reinforced patient teachings

Metabolic Alkalosis Etiology

  • Nasogastric suction, diuretic therapy, and prolonged vomiting can cause metabolic alkalosis

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