Podcast
Questions and Answers
What defines major haemorrhage in terms of blood loss in a 70kg male?
What defines major haemorrhage in terms of blood loss in a 70kg male?
- 5 liters in less than 24 hours
- 50% blood volume in less than 3 hours
- Bleeding more than 150ml/min
- All of the above (correct)
Which statement about the coagulopathy component of the lethal triad is accurate?
Which statement about the coagulopathy component of the lethal triad is accurate?
- Loss of red blood cells and clotting factors impacts clotting. (correct)
- TXA enhances clotting enzyme activity.
- Fibrinolysis occurs after clot formation without any exceptions.
- Microclots are beneficial and not broken down.
What is the role of calcium in the clotting cascade?
What is the role of calcium in the clotting cascade?
- It directly breaks down fibrin.
- It initiates the extrinsic pathway.
- It enhances the production of platelets.
- It is essential for activating clotting factors. (correct)
What is a potential consequence of administering large volumes of FFP?
What is a potential consequence of administering large volumes of FFP?
In a situation of significant haemorrhage, what treatment should be prioritized?
In a situation of significant haemorrhage, what treatment should be prioritized?
Which of the following is true regarding FFP and cryoprecipitate?
Which of the following is true regarding FFP and cryoprecipitate?
What characterizes a 3rd degree burn?
What characterizes a 3rd degree burn?
Which zone of injury involves maximum cell damage and death, leading to coagulation?
Which zone of injury involves maximum cell damage and death, leading to coagulation?
What systemic response occurs when burns affect 30% of tissue areas?
What systemic response occurs when burns affect 30% of tissue areas?
Which of the following represents a primary metabolic change following a significant burn injury?
Which of the following represents a primary metabolic change following a significant burn injury?
What is an essential aspect of respiratory management for burn patients?
What is an essential aspect of respiratory management for burn patients?
What physiological process occurs rapidly in response to changes in pH?
What physiological process occurs rapidly in response to changes in pH?
Which condition is indicated by an HCO₃⁻ level above 26 mmol/L?
Which condition is indicated by an HCO₃⁻ level above 26 mmol/L?
If the kidneys are not producing enough bicarbonate, what type of issue is likely present?
If the kidneys are not producing enough bicarbonate, what type of issue is likely present?
What is the normal range for Base Excess (BE) in a blood gas analysis?
What is the normal range for Base Excess (BE) in a blood gas analysis?
In mixed acid-base disorders, how do CO₂ and HCO₃⁻ behave?
In mixed acid-base disorders, how do CO₂ and HCO₃⁻ behave?
Which of the following indicates compensatory metabolic acidosis?
Which of the following indicates compensatory metabolic acidosis?
What likely caused the observed blood gas results in the case study example?
What likely caused the observed blood gas results in the case study example?
What is the primary characteristic of a Level 1 critical care patient?
What is the primary characteristic of a Level 1 critical care patient?
When analyzing blood gas results, which value is critical in assessing respiratory status?
When analyzing blood gas results, which value is critical in assessing respiratory status?
Which type of equipment is essential for monitoring critically ill patients during transfer?
Which type of equipment is essential for monitoring critically ill patients during transfer?
An increased acid load leads to which primary reaction in the body?
An increased acid load leads to which primary reaction in the body?
In what situation would a patient be classified as Level 2 in critical care?
In what situation would a patient be classified as Level 2 in critical care?
What is a crucial responsibility of an Operating Department Practitioner (ODP) in the transfer team?
What is a crucial responsibility of an Operating Department Practitioner (ODP) in the transfer team?
What indicates that a mixed acid-base disorder might be present?
What indicates that a mixed acid-base disorder might be present?
What does SBAR stand for in the context of handover?
What does SBAR stand for in the context of handover?
Which statement is true regarding Level 3 critical care patients?
Which statement is true regarding Level 3 critical care patients?
What is one of the key pieces of equipment that a transfer team should prepare for critically ill patients?
What is one of the key pieces of equipment that a transfer team should prepare for critically ill patients?
Which of the following best describes the role of the anesthetist during the transfer of critical patients?
Which of the following best describes the role of the anesthetist during the transfer of critical patients?
What physiological change is indicated by decreased saturation in a patient?
What physiological change is indicated by decreased saturation in a patient?
Which statement accurately describes the pharyngeal reflex?
Which statement accurately describes the pharyngeal reflex?
What is the primary function of the laryngeal reflex?
What is the primary function of the laryngeal reflex?
How does general anesthesia (GA) affect airway reflexes?
How does general anesthesia (GA) affect airway reflexes?
Which anatomical feature of the right bronchus distinguishes it from the left bronchus?
Which anatomical feature of the right bronchus distinguishes it from the left bronchus?
What does the acronym BURP represent in airway management?
What does the acronym BURP represent in airway management?
Which structure serves to surround and support the vocal cords?
Which structure serves to surround and support the vocal cords?
What is the effect of local anesthesia (LA) on airway reflexes?
What is the effect of local anesthesia (LA) on airway reflexes?
Which of the following describes the structure and function of the larynx?
Which of the following describes the structure and function of the larynx?
What role does the vallecular space play in airway management?
What role does the vallecular space play in airway management?
What is the primary role of the SA Node in the heart?
What is the primary role of the SA Node in the heart?
Which phase of the cardiac action potential is characterized by Na+ channels opening?
Which phase of the cardiac action potential is characterized by Na+ channels opening?
What is indicated by the PR interval in cardiac rhythm?
What is indicated by the PR interval in cardiac rhythm?
What happens to potassium (K+) during the early repolarization of a cardiac action potential?
What happens to potassium (K+) during the early repolarization of a cardiac action potential?
Which of the following statements accurately describes a cardiac cell at rest?
Which of the following statements accurately describes a cardiac cell at rest?
What is the primary immunoglobulin responsible for the allergic response in anaphylaxis?
What is the primary immunoglobulin responsible for the allergic response in anaphylaxis?
Which of the following is NOT a symptom of Grade 2 anaphylaxis?
Which of the following is NOT a symptom of Grade 2 anaphylaxis?
What mechanism causes bronchoconstriction during an anaphylactic reaction?
What mechanism causes bronchoconstriction during an anaphylactic reaction?
In severe systemic anaphylaxis, which cardiovascular condition is primarily associated with the release of histamine?
In severe systemic anaphylaxis, which cardiovascular condition is primarily associated with the release of histamine?
What treatment is typically administered first when a patient experiences anaphylaxis?
What treatment is typically administered first when a patient experiences anaphylaxis?
Flashcards
Zone of Coagulation
Zone of Coagulation
The area of a burn where the most damage occurs, resulting in cell death and impaired circulation due to coagulation.
Zone of Stasis
Zone of Stasis
The area surrounding the zone of coagulation where tissue perfusion is reduced, but cells may still be salvageable if treated promptly. If untreated, it can become irreversible and lead to complications like infection and edema.
Zone of Hyperemia
Zone of Hyperemia
The outermost area of a burn where blood flow is increased due to inflammation. This is a natural response to injury.
Insulin Resistance in Burns
Insulin Resistance in Burns
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Lethal Triad in Burns
Lethal Triad in Burns
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What is Anaphylaxis?
What is Anaphylaxis?
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How does the immune system trigger Anaphylaxis?
How does the immune system trigger Anaphylaxis?
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What are the main effects of histamine in Anaphylaxis?
What are the main effects of histamine in Anaphylaxis?
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How is Anaphylaxis treated?
How is Anaphylaxis treated?
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How does Anaphylaxis affect the cardiovascular system?
How does Anaphylaxis affect the cardiovascular system?
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Major Haemorrhage
Major Haemorrhage
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Body's Response to Blood Loss
Body's Response to Blood Loss
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Coagulopathy
Coagulopathy
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Fibrin Formation
Fibrin Formation
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Fibrinolysis
Fibrinolysis
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Role of Calcium in Clotting
Role of Calcium in Clotting
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Level 0 Critical Care
Level 0 Critical Care
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Level 1 Critical Care
Level 1 Critical Care
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Level 2 Critical Care
Level 2 Critical Care
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Level 3 Critical Care
Level 3 Critical Care
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Portable Monitoring
Portable Monitoring
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Portable Ventilator
Portable Ventilator
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SBAR Handover
SBAR Handover
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Transfer of Critically Ill
Transfer of Critically Ill
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Low Saturation
Low Saturation
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Beavals
Beavals
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Cricoid Pressure
Cricoid Pressure
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Thyroid Cartilage
Thyroid Cartilage
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Tongue & Airway
Tongue & Airway
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Reflexes & Anesthesia
Reflexes & Anesthesia
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Pharyngeal Reflex
Pharyngeal Reflex
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Laryngeal Reflex
Laryngeal Reflex
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Bronchial Anatomy
Bronchial Anatomy
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Vallecular Space
Vallecular Space
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What are autorhythmic cells?
What are autorhythmic cells?
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What is the SA Node?
What is the SA Node?
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What is the AV Node?
What is the AV Node?
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What is a polarized cardiac cell?
What is a polarized cardiac cell?
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What is depolarization?
What is depolarization?
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Compensation (blood gas)
Compensation (blood gas)
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Respiratory Compensation
Respiratory Compensation
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Metabolic Compensation
Metabolic Compensation
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Base Excess (BE)
Base Excess (BE)
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HCO₃⁻ (Bicarbonate)
HCO₃⁻ (Bicarbonate)
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Respiratory Alkalosis
Respiratory Alkalosis
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Respiratory Acidosis
Respiratory Acidosis
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Metabolic Alkalosis
Metabolic Alkalosis
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Metabolic Acidosis
Metabolic Acidosis
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Mixed Acid-Base Disorders
Mixed Acid-Base Disorders
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Study Notes
Burns
- Skin:
- Epidermis: 5 layers / Prevents fluid loss
- Dermis: 2 layers / Body temp regulates
- Deepest layers → Deest layers take 2-3 weeks
- Epidermis can't regenerate without dermis
Types of Burns
- Injury to skin: radiation, radioactivity, electricity, friction or chemicals
- 1st degree: superficial - no damage to dermis
- 2nd degree:
- superficial dermal - fluid, blisters, painful
- deep dermal - can lead to compartment syndrome if circumferential
- 3rd degree: full thickness, epidermis + dermis + nerves destroyed - no pain, Black + leathery
Pathophysiology (local response)
- Zone of coagulation: max damage (clot) - cell death, damage to circulation
- Zone of stasis: decreased tissue perfusion - tries to pull oxygen in - can become infection, oedema
- Zone of hyperaemia: blood flow increases due to inflammation (Vascular dilation + increased circulation + histamine)
Systemic Response
- Release of cytokines + inflammatory mediators once burn reaches 30% tissue areas = capillary permeability.
- Peripheral + splanchnic vasoconstriction - due to release of catecholamines (body's adrenaline), vasopressin - reduces cardiac contractility - 1HR reduces because of O2 → less vol → less contractility - tries to maintain CO2
- Together = systemic hypotension + end organ hypoperfusion → Hypovolemic shock/Distributive Shock
Respiratory Changes
- Stabilize airway +
- Bronchoconstriction = cytokines released + more resistance + ventilation (decreased) + more O2 + CO2 out - loss of fluids - less oxygen-carrying capacity - decreased perfusion
Metabolic Changes
- Hypermetabolism → met demand = breakdown of molecules
- Splanchnic hypoperfusion - needs early aggressive intervention
- Increased glucose production (glycogenolysis/gluconeogenesis) to generate glucose from non-carbohydrate sources (glycogen).
- ↓7 leads to decrease in glucose uptake + clearance from the body.
- Grave crystalloids - mixed evidence of insulin
- Risk of hypoglycemia
Lethal Triad
- Loss of volume = loss of O2 = lactic acid = metabolic acidosis
- Hypothermia - loss of dermis = ↓temp
- Burns around mouth? smaller tubes?
- Breathing? Resuscitation via tracheostomy
- Bronchoscopy: burns to chest?
- Cardio: Replace the lost fluid vol, IV access, warming, TPV formula + increase O2-carrying capacity, blood pressure, respiratory status.
- Disability: O2 going to brain, CV compromise - need early intubation
- treat temp above 42.2°C
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Description
Test your knowledge on crucial concepts in emergency medicine, specifically focusing on major haemorrhage, coagulopathy, and burn injuries. Explore the physiological responses and treatment protocols relevant to critical situations such as significant blood loss and burn management.