Suprachoroidal Uvea Quiz and Flashcards

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Questions and Answers

What is the origin of the iris sphincter muscle?

Neural crest

Mesoderm

Ectoderm (correct)

Endoderm

At what point in development does the dilatator muscle of the iris begin to develop myofibrils?

4th month

3rd month

6th month (correct)

5th month

What component of the anterior border layer of the iris is of neural crest origin?

Stroma (correct)

Ciliary processes

Myofilaments

Mesenchymal cells

During which month of development does the outer layer of the optic cup become the outer pigmented epithelium of the ciliary body?

3rd month Signup and view all the answers

What is the embryonic origin of the stroma and ciliary muscle of the ciliary body?

Mesoderm Signup and view all the answers

Which structure becomes level with the anterior border of the future trabecular meshwork during postnatal eye development in mice?

Chamber angle cells Signup and view all the answers

What differentiates into the chamber angle, trabecular meshwork, and Schlemm’s canal during eye development?

Group of neural crest cells Signup and view all the answers

When does aqueous humor production begin during gestation?

4-6 months Signup and view all the answers

Which ocular structure becomes the choriocapillaris during anterior segment development?

Choroid mesenchyme Signup and view all the answers

What happens to the lens vesicle during eye development?

It becomes invaginated into the optic cup Signup and view all the answers

What covers the trabecular beams in the chamber angle during development?

Trabecular meshwork cells Signup and view all the answers

What is the role of the scleral vessels next to the chamber angle in eye development?

Forming Schlemm's canal Signup and view all the answers

Which layer of the optic cup becomes the retinal pigment epithelium (RPE)?

Outer layer Signup and view all the answers

What becomes evident in the 5th month of anterior segment development in terms of vessels?

Vortex veins Signup and view all the answers

Which layer of the retina is located between the ganglion cell layer and the bipolar cell layer?

Inner plexiform layer Signup and view all the answers

What is the function of Bruch's membrane?

Preventing light scattering Signup and view all the answers

Which layer of the retina contains nuclei of rods and cones?

Cone (and rod) layer Signup and view all the answers

What is the main structural component of the outermost layer of Bruch's membrane?

Collagen fibers Signup and view all the answers

Which layer of the retina is responsible for initial processing of visual signals from photoreceptors?

Bipolar cell layer Signup and view all the answers

What creates a tight adhesion between the choroid and the outer pigmented layer of the retina?

Basement membrane of RPE cells Signup and view all the answers

The nuclei of which cells are found in the ganglion cell layer of the retina?

Ganglion cells Signup and view all the answers

Which layer of the retina is primarily involved in conducting action potentials to the brain?

Ganglion cell layer Signup and view all the answers

Which layer of the choroid contains collagen bands, fibroblasts, and melanocytes?

Choroidal Stroma Signup and view all the answers

What allows the suprachoroidal space to carry the long posterior ciliary arteries and nerves?

Collagen bands in the suprachoroid lamina Signup and view all the answers

Which layer of choroidal vessels forms capillary beds known as choriocapillaris?

Haller's layer Signup and view all the answers

What is the main function of pericytes in the choriocapillaris?

Regulate local blood flow Signup and view all the answers

What type of innervation controls vasoconstriction in the choroidal vessels?

Autonomic nervous system - Sympathetic stimulation Signup and view all the answers

What is the purpose of the choroid lamina fuscha (suprachoroid lamina) in maintaining tissues' integrity?

Allows vascular swelling without detachment Signup and view all the answers

What characteristic differentiates choriocapillaris capillaries from ordinary capillaries?

$3-4$ red blood cells can pass through at once Signup and view all the answers

Which type of stimulation results in increased choroidal blood flow?

$N_2O$ responsive stimulation Signup and view all the answers

What is the role of mesenchymal cells (ME) in eye development based on the text?

Migration into the space between the anterior epithelium of the lens vesicle and the surface ectoderm Signup and view all the answers

Where does the hyaloid artery (HA) enter the optic cup during eye development?

Incompletely inferior at the embryonic fissure (EF) Signup and view all the answers

What happens to mesenchymal cells at E 13.5-14.5 during eye development?

They condense to form several flat layers separated by an extracellular matrix Signup and view all the answers

Which part of the optic cup forms the neural retina (Re) during eye development?

The inner layer Signup and view all the answers

What is the function of the retinal pigmented epithelium (PE) during eye development?

Contributes to eye pigmentation Signup and view all the answers

How do primary lens fibers contribute to eye development?

By elongating to close the lumen of the lens vesicle Signup and view all the answers

Study Notes

Iris Development

The iris sphincter muscle originates from the neural crest.
The dilatator muscle of the iris begins to develop myofibrils at E 13.5-14.5.
The anterior border layer of the iris is of neural crest origin.

Ciliary Body Development

The stroma and ciliary muscle of the ciliary body are of neural crest origin.
The outer layer of the optic cup becomes the outer pigmented epithelium of the ciliary body during the 4th month of development.

Eye Development

The trabecular meshwork becomes level with the anterior border of the future trabecular meshwork during postnatal eye development in mice.
The chamber angle, trabecular meshwork, and Schlemm's canal differentiate from the mesenchyme during eye development.
Aqueous humor production begins during the 3rd month of gestation.

Ocular Structure Development

The lens vesicle invaginates during eye development.
The scleral vessels next to the chamber angle play a role in eye development by allowing the suprachoroidal space to carry the long posterior ciliary arteries and nerves.
The choriocapillaris forms from the outer layer of the optic cup during anterior segment development.

Retina Development

The retinal pigment epithelium (RPE) forms from the outer layer of the optic cup.
The layer between the ganglion cell layer and the bipolar cell layer is the inner nuclear layer.
The photoreceptor layer contains nuclei of rods and cones.
The outermost layer of Bruch's membrane is composed of elastic fibers.

Retina Function

Bruch's membrane allows the RPE to adhere to the choroid.
The outer plexiform layer is responsible for initial processing of visual signals from photoreceptors.
The ganglion cell layer contains nuclei of ganglion cells, which are responsible for conducting action potentials to the brain.

Choroid Development

The choroid contains collagen bands, fibroblasts, and melanocytes in the stroma.
The choroid forms capillary beds known as choriocapillaris in the choroidal vessels.
Pericytes in the choriocapillaris play a role in regulating blood flow.
The choroid lamina fuscha (suprachoroid lamina) maintains tissue integrity by allowing the suprachoroidal space to carry the long posterior ciliary arteries and nerves.

Choriocapillaris Function

Choriocapillaris capillaries are fenestrated, which allows for increased permeability.
Choroidal blood flow increases in response to neural stimulation.
The main function of the choroid is to provide oxygen and nutrients to the outer retina.

Early Eye Development

Mesenchymal cells (ME) play a role in eye development by forming the stroma and ciliary muscle of the ciliary body.
The hyaloid artery (HA) enters the optic cup during eye development.
Mesenchymal cells differentiate into the sclera and choroid at E 13.5-14.5.
The neural retina (Re) forms from the inner layer of the optic cup.
The retinal pigmented epithelium (PE) plays a role in eye development by allowing the RPE to adhere to the choroid.
Primary lens fibers contribute to eye development by forming the lens vesicle.

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Description

Test your knowledge on the development of the eye during the embryonic stage, including the formation of the optic cup, migration of mesenchymal cells, and the structure of the retina. This quiz covers key events and structures involved in early eye development.

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