Embryology: Pleuropericardial Membrane
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Questions and Answers

What is the primary role of the pleuropericardial membrane in an embryo?

  • To form the muscular layer of the heart
  • To separate the pericardial cavity from the pleural cavities (correct)
  • To regulate respiratory activity in the embryo
  • To facilitate blood flow within the heart
  • Which embryonic tissue layer contributes to the formation of the pleuropericardial membrane?

  • Somatic mesoderm (correct)
  • Ectoderm
  • Endoderm
  • Splanchnic mesoderm
  • What structure does the pleuropericardial membrane eventually develop into?

  • Peritoneal cavity
  • Muscle tissue of the diaphragm
  • Fibrous pericardium surrounding the heart (correct)
  • Pleural sacs
  • In the context of embryonic development, where is the pleuropericardial membrane located?

    <p>Between the pericardial and pleural cavities</p> Signup and view all the answers

    What additional structure is indicated in the diagram along with the pleuropericardial membrane?

    <p>Septum transversum</p> Signup and view all the answers

    Which adult mesentery is derived from the ventral mesentery?

    <p>Falciform ligament</p> Signup and view all the answers

    Which ligaments are classified as components of the lesser omentum derived from the ventral mesentery?

    <p>Hepatoduodenal ligament and hepatogastric ligament</p> Signup and view all the answers

    Which of the following structures is NOT derived from the embryonic mesentery?

    <p>Mesochium</p> Signup and view all the answers

    Which adult mesentery includes the mesoappendix as a component?

    <p>Mesentery of the small intestine</p> Signup and view all the answers

    What structure serves as the precursor to the central tendon of the diaphragm?

    <p>Septum transversum</p> Signup and view all the answers

    Which component is responsible for providing muscle to the peripheral portions of the definitive diaphragm?

    <p>Lateral body wall</p> Signup and view all the answers

    During which weeks does the closure of the pericardioperitoneal canal occur?

    <p>Weeks 5 to 7</p> Signup and view all the answers

    What role do the pleuroperitoneal membranes play in diaphragm development?

    <p>Seal off the pleural cavities from the peritoneal cavity</p> Signup and view all the answers

    Which structure develops into the crura of the diaphragm in adults?

    <p>Dorsal mesentery of the esophagus</p> Signup and view all the answers

    What primarily causes congenital diaphragmatic hernia?

    <p>Failure of the pleuroperitoneal membrane to develop</p> Signup and view all the answers

    Which clinical sign is least likely to be associated with congenital diaphragmatic hernia in newborns?

    <p>Polyhydramnios</p> Signup and view all the answers

    In which location is congenital diaphragmatic hernia most commonly found?

    <p>Left posterolateral side</p> Signup and view all the answers

    What is the most serious consequence of congenital diaphragmatic hernia?

    <p>Pulmonary hypoplasia</p> Signup and view all the answers

    Which method is effective for prenatal detection of congenital diaphragmatic hernia?

    <p>Ultrasonography</p> Signup and view all the answers

    Study Notes

    Pleuropericardial Membrane

    • The pleuropericardial membrane is composed of somatic mesoderm.
    • It acts as a divider between the pericardial cavity and pleural cavities.
    • The pleuropericardial membranes further develop into the fibrous pericardium surrounding the heart.
    • A sagittal section of an embryo showcases the relationship between the pericardial cavity, pleural cavities, and the pleuropericardial membrane.
    • The septum transversum is also visible in the diagram.
    • A red arrow in the diagram indicates the flow of fluid.

    Adult Mesenteries Development

    • Adult mesenteries originate from the ventral and dorsal mesenteries present in the embryo's peritoneal cavity.
    • The ventral mesentery gives rise to the lesser omentum, which includes the hepatoduodenal and hepatogastric ligaments.
    • The falciform ligament, coronary ligament, and triangular ligament also develop from the ventral mesentery.
    • The greater omentum, including the gastrorenal, gastrosplenic, gastrocolic, and splenorenal ligaments, originates from the ventral mesentery.
    • The mesentery of the small intestine, mesoappendix, transverse mesocolon, and sigmoid mesocolon are all derived from the ventral mesentery.
    • All adult mesenteries ultimately originate from the dorsal mesentery.

    Diaphragm Development

    • The septum transversum is a thick mesoderm mass forming the central tendon of the diaphragm.
    • Paired pleuroperitoneal membranes are sheets of somatic mesoderm, contributing to the diaphragm's crura.
    • The dorsal mesentery of the esophagus forms the diaphragm's crura in adults.
    • The lateral body wall, provides muscle to the peripheral parts of the definitive diaphragm.

    Pericardioperitoneal Canal Closure

    • The pleuroperitoneal membranes extend from the posterior body wall and connect to the septum transversum between weeks 5 and 7.
    • This closure prevents communication between the pleural and peritoneal cavities.
    • The membranes form the posterior parts of the diaphragm.
    • Muscle fibers from the body wall invade the developing diaphragm as shown by arrows in diagram B.

    Congenital Diaphragmatic Hernia

    • A condition where abdominal contents protrude into the chest cavity due to incomplete diaphragm development.
    • The pleuroperitoneal membrane, responsible for diaphragm formation, fails to develop or fuse completely.
    • Most cases are located on the left side of the diaphragm.
    • Can be life-threatening due to compression of the lungs by the herniated abdominal organs, leading to underdeveloped lungs (pulmonary hypoplasia).
    • Prenatal ultrasound can detect diaphragmatic hernias.
    • Clinical symptoms in newborns include a flat abdomen, difficulty breathing, loud breathing sounds, bowel sounds heard over the chest, and a bluish skin discoloration (cyanosis).

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    Description

    This quiz focuses on the pleuropericardial membrane, its structure, and its role in separating the pericardial and pleural cavities. It also discusses the development into the fibrous pericardium and includes diagrams that illustrate these concepts. Test your understanding of this essential aspect of embryological anatomy.

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