Embryology of Pancreas and Small Intestine

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

During which week does the duodenal loop rotate clockwise with the stomach to the right?

5th week

8th week

4th week

6th week (correct)

From which part of the primordial gut does the duodenum develop?

Caudal part of foregut (correct)

Cranial part of foregut

Caudal part of midgut

Cranial part of midgut

At what point is the junction of the 2 parts of the gut located during the 5th week?

Just below or distal to the origin of bile duct (correct)

At the level of liver bud

Just above or proximal to the origin of bile duct

At the level of spleen bud

When is the lumen of the duodenum temporarily obliterated due to proliferation of its epithelial cells?

$8^{th}$ week Signup and view all the answers

From which embryonic layer does the duodenum develop?

$Endoderm$ Signup and view all the answers

During which week does the duodenal loop form and project ventrally, forming a C-shaped loop?

$5^{th}$ week Signup and view all the answers

Where does the duodenal loop come to lie during weeks 5 and 6?

$Posterior abdominal wall retroperitoneally$ Signup and view all the answers

What causes temporary obliteration of duodenal lumen at end of week 8?

Proliferation of endodermal cells Signup and view all the answers

Where does junction of two parts of gut lie during 5th week?

Just below or distal to origin of bile duct (C &D) Signup and view all the answers

When is duodenal loop formed and projected ventrally, forming a C-shaped loop?

5th week Signup and view all the answers

Which part of the pancreas does the ventral pancreatic bud form?

Lower part of the head Signup and view all the answers

Around which artery does the midgut loop rotate around its axis?

Superior mesenteric artery Signup and view all the answers

Which limb of the midgut loop gives rise to the jejunum & ileum?

The jejunum & ileum Signup and view all the answers

What is an umbilical hernia?

Resulting from imperfect closure of the umbilicus Signup and view all the answers

A small pouch from the ileum.

Covered by the epithelium of the umbilical cord. Signup and view all the answers

What direction is the duodenal loop rotated?

To the right Signup and view all the answers

From which part is most of the pancreas derived?

The dorsal pancreatic bud. Signup and view all the answers

What enlarged organ presses the duodenum & pancreas against the posterior abdominal wall?

Colon Signup and view all the answers

How does the midgut loop communicate with the yolk sac?

Vitelline duct or yolk stalk Signup and view all the answers

During embryonic development, when does the duodenum normally recanalize?

End of week 8 Signup and view all the answers

From which buds does the pancreas develop?

Ventral and dorsal buds Signup and view all the answers

What structures form the main pancreatic duct and accessory pancreatic duct?

Ventral bud and dorsal bud, respectively Signup and view all the answers

At what stage do pancreatic islets develop and start secreting insulin?

Early fetal period (around 10 weeks) Signup and view all the answers

From which part of the embryonic gut does the duodenum derive?

Cranial part of midgut Signup and view all the answers

When does the midgut return to the abdomen during embryonic development?

Week 10 Signup and view all the answers

What is Meckel's diverticulum?

A congenital anomaly where a pouch forms in the wall of the intestine due to failure to return to the abdominal cavity during week 10 Signup and view all the answers

Where are the pancreas and small intestine located in relation to the peritoneum?

Retroperitoneal structures, located behind the peritoneum Signup and view all the answers

Study Notes

Embryonic period lasts until end of week 8, during which the duodenum normally recanalizes but can lead to congenital anomalies like duodenal stenosis or atresia
Pancreas develops from two buds: ventral (forms liver & gallbladder) and dorsal (larger, forms most of pancreas)
Pancreatic buds fuse together and move to the dorsal mesentery, forming the main pancreatic duct from the ventral bud and accessory pancreatic duct from the dorsal bud
Pancreatic islets develop from parenchymatous pancreatic tissue and secrete insulin during early fetal period (around 10 weeks)
Small intestine is developed from the caudal foregut and cranial midgut, with the duodenum deriving from the cranial part of midgut
During embryonic development, the midgut forms a U-shaped loop that projects into the umbilical cord due to a temporary lack of space in the abdominal cavity, eventually returning to the abdomen during week 10
Congenital anomalies of the pancreas, such as accessory pancreatic tissue, annular pancreas, or Meckel's diverticulum, can result from developmental abnormalities.
Meckel's diverticulum is a congenital anomaly where the intestines fail to return to the abdominal cavity during week 10, resulting in the formation of a pouch in the wall of the intestine.
The pancreas and small intestine are retroperitoneal structures, meaning they are located behind the peritoneum.
The duodenum is the most fixed part of the small intestine and has no mesentery, while the rest of the small intestine is supported by a mesentery that allows for free movement.
The mesentery of the small intestine undergoes fixation during development, changing from a continuous mesentery with the ascending colon to a fan-shaped mesentery with a new line of attachment to the posterior abdominal wall.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Description

Test your knowledge on the embryological development of the duodenum, pancreas, and small intestine, as well as congenital anomalies related to these structures.