Embryology: 2nd Week of Development

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Questions and Answers

What differentiates into two layers over the embryoblast on day 8?

  • Syncytiotrophoblast
  • Trophoblast (correct)
  • Endometrial stroma
  • Cytotrophoblast

What type of cells form the outer layer of the trophoblast on day 8?

  • Syncytiotrophoblast (correct)
  • Cytotrophoblast
  • Multinucleated zone without clear cell boundaries
  • Mononucleated cells

What is formed by the cells of the inner cell mass or embryoblast on day 8?

  • Endometrial stroma
  • Bilaminar embryonic disc
  • Blastocyst cavity
  • Hypoblast and epiblast layer (correct)

What appears within the epiblast on day 8?

<p>Small cavity (B)</p> Signup and view all the answers

Where is the blastocyst partially embedded on day 8?

<p>Endometrial stroma (A)</p> Signup and view all the answers

Describe the structure of the blastocyst on day 8 of development.

<p>The blastocyst on day 8 of development consists of a trophoblast partially embedded in the endometrial stroma, with the inner layer differentiating into cytotrophoblast and syncytiotrophoblast, and the embryoblast forming a bilaminar embryonic disc with epiblast and hypoblast layers.</p> Signup and view all the answers

Explain the differentiation of the trophoblast on day 8.

<p>On day 8, the trophoblast differentiates into two layers: the inner layer forms cytotrophoblast with mononucleated cells, and the outer layer forms syncytiotrophoblast with multinucleated zone without clear cell boundaries.</p> Signup and view all the answers

Discuss the development of the embryoblast on day 8.

<p>On day 8, the cells of the inner cell mass or embryoblast differentiate into two layers: hypoblast consisting of small high cuboidal cells near the blastocyst cavity, and epiblast forming a flat disc with columnar cells near the amniotic cavity.</p> Signup and view all the answers

What is the significance of the small cavity appearing within the epiblast on day 8?

<p>The small cavity appearing within the epiblast on day 8 contributes to the formation of the bilaminar embryonic disc, consisting of epiblast and hypoblast layers, which is essential for further embryonic development.</p> Signup and view all the answers

Explain the process of cell migration within the trophoblast on day 8.

<p>On day 8, the cells in the cytotrophoblast divide and migrate into the syncytiotrophoblast, forming multinucleated zone without clear cell boundaries within the outer layer of the trophoblast.</p> Signup and view all the answers

Flashcards

Syncytiotrophoblast

Outer layer of trophoblast; multinucleated zone

Cytotrophoblast

Inner layer, mononucleated cells

Day 8: Two-Layer Formation

Embryoblast differentiates into two layers

Hypoblast

Small high cuboidal cells near the blastocyst cavity

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Epiblast

Flat disc with columnar cells near the amniotic cavity

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Amniotic Cavity (Early)

Cavity that appears within the epiblast

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Trophoblast Differentiation

Differentiates into cytotrophoblast and syncytiotrophoblast

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Cytotrophoblast Cells

Migrate into the syncytiotrophoblast

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Blastocyst on Day 8

Has a trophoblast partially embedded

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Embryoblast

The inner cell mass become the hypoblast and epiblast layer

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Study Notes

  • The second week of development (Bilaminar germ disc) is the focus of this lecture.
  • The blastocyst, a fluid-filled structure, is partially embedded in the endometrial stroma on Day 8.
  • The trophoblast layer of the blastocyst differentiates into two layers: an outer layer (syncytio trophoblast) and an inner layer (cyto trophoblast). The outer layer has multinucleated cells, while the inner layer has mononucleated cells.
  • Cells of the inner cell mass or embryoblast differentiate into two layers: the epiblast and hypoblast. The epiblast forms the embryyonic disc and has small, high, cuboidal, and columnar cells, while the hypoblast forms the extraembryonic membranes.
  • A small cavity appears within the epiblast on Day 8, leading to the formation of the blastocyst cavity. The two layers then form a flat disc called the bilaminar embryonic disc.

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