E.histolytica Pathogenesis and Clinical Manifestations
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Questions and Answers

What is the role of Gal lectin in E.histolytica pathogenesis?

  • Engulfment of mucosal cells
  • Activation of caspase-3
  • Adhesion to colonic mucosa (correct)
  • Induction of bacterial peritonitis

    • Which enzyme activation leads to apoptotic death of mucosal cells by E.histolytica?

  • Caspase-1
  • Caspase-7
  • Caspase-3 (correct)
  • Caspase-9

    • How does Amoebic Colitis typically present clinically?

  • Sudden onset of fever and upper left quadrant pain
  • Gradual onset of abdominal pain and diarrhea with blood and mucus in stools (correct)
  • Sudden onset of abdominal cramps and constipation
  • Gradual onset of abdominal pain and diarrhea without blood or mucus in stools

    • What is the most common extraintestinal form of amebiasis?

    <p>Amoebic Liver Abscess</p> Signup and view all the answers

    What is the cardinal symptom of Amoebic Liver Abscess (ALA)?

    <p>Fever and pain in the upper right quadrant</p> Signup and view all the answers

    What is the most serious complication of amebic colitis?

    <p>Colonic perforation and secondary bacterial peritonitis</p> Signup and view all the answers

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