Podcast
Questions and Answers
Which of the following is NOT a common bacteria associated with sepsis?
Which of the following is NOT a common bacteria associated with sepsis?
- Staphylococcus aureus
- Streptococcus pyogenes
- Candida albicans (correct)
- Escherichia coli
What is the primary purpose of stimulating systemic overproduction of inflammatory cytokines in experimental models of septic shock?
What is the primary purpose of stimulating systemic overproduction of inflammatory cytokines in experimental models of septic shock?
- To promote resolution of inflammation
- To mimic the immune response observed in sepsis patients (correct)
- To cause an imbalance in the immune system
- To increase pathogen clearance
Which phase of the immune response to infection involves the return to homeostasis after pathogen clearance?
Which phase of the immune response to infection involves the return to homeostasis after pathogen clearance?
- Resolution phase (correct)
- Chronic inflammation phase
- Inflammatory phase
- Adaptive immunity phase
Which chemokine recruits neutrophils from blood to infected tissue?
Which chemokine recruits neutrophils from blood to infected tissue?
What is the effect of TNFα on vascular endothelium?
What is the effect of TNFα on vascular endothelium?
Which molecule is involved in tight binding between leukocytes and endothelium during extravasation?
Which molecule is involved in tight binding between leukocytes and endothelium during extravasation?
Which cytokine is responsible for inflammatory activation of leukocytes and increasing antibody production by B cells?
Which cytokine is responsible for inflammatory activation of leukocytes and increasing antibody production by B cells?
Which class of molecules are specifically recognized by pattern recognition receptors (PRRs) and are shared by a category of pathogens?
Which class of molecules are specifically recognized by pattern recognition receptors (PRRs) and are shared by a category of pathogens?
What did Charles Janeway propose in 1989 regarding the stimulation of adaptive immunity?
What did Charles Janeway propose in 1989 regarding the stimulation of adaptive immunity?
Which of the following is a characteristic of pattern recognition receptors (PRRs)?
Which of the following is a characteristic of pattern recognition receptors (PRRs)?
Which of the following is a primary function of Toll-like receptors (TLRs) in the innate immune response?
Which of the following is a primary function of Toll-like receptors (TLRs) in the innate immune response?
What is a common outcome of PAMP/PRR recognition in terms of transcriptional outputs?
What is a common outcome of PAMP/PRR recognition in terms of transcriptional outputs?
In the context of the immune response, what is the main role of chemokines?
In the context of the immune response, what is the main role of chemokines?
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