Questions and Answers
Which of the following is NOT a common bacteria associated with sepsis?
Candida albicans
What is the primary purpose of stimulating systemic overproduction of inflammatory cytokines in experimental models of septic shock?
To mimic the immune response observed in sepsis patients
Which phase of the immune response to infection involves the return to homeostasis after pathogen clearance?
Resolution phase
Which chemokine recruits neutrophils from blood to infected tissue?
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What is the effect of TNFα on vascular endothelium?
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Which molecule is involved in tight binding between leukocytes and endothelium during extravasation?
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Which cytokine is responsible for inflammatory activation of leukocytes and increasing antibody production by B cells?
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Which class of molecules are specifically recognized by pattern recognition receptors (PRRs) and are shared by a category of pathogens?
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What did Charles Janeway propose in 1989 regarding the stimulation of adaptive immunity?
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Which of the following is a characteristic of pattern recognition receptors (PRRs)?
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Which of the following is a primary function of Toll-like receptors (TLRs) in the innate immune response?
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What is a common outcome of PAMP/PRR recognition in terms of transcriptional outputs?
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In the context of the immune response, what is the main role of chemokines?
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